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- W4360614923 abstract "Patients with ANCA-associated vasculitis (AAV) cause extreme alertness during the coronavirus disease 2019 (COVID-19) pandemic, associated with many factors: the initial damage to the respiratory system (upper respiratory tract, lungs) and kidneys, immunosuppressive treatments, difficult prognosis of COVID-19 with the risk of AAV exacerbation. We present a clinical case of а moderate COVID-19 in a patient with granulomatosis with polyangiitis, who received anti-B cell therapy with rituximab (RTX) for a long time. Coronavirus pneumonia developed one year after RTX, while B-lymphocyte depletion persisted. In order to achieve an adequate antiviral immune response and prevent hyperinflammation, treatment was carried out with antiviral drugs, anticoagulants, convalescent plasma, human normal immunoglobulin, and interleukin-6 antagonist tocilizumab. Possible predictors of severe COVID-19 in patients with AAV are discussed." @default.
- W4360614923 created "2023-03-24" @default.
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- W4360614923 date "2023-03-02" @default.
- W4360614923 modified "2023-10-15" @default.
- W4360614923 title "COVID-19 in a patient with granulomatosis with polyangiitis: Management tactics" @default.
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- W4360614923 doi "https://doi.org/10.47360/1995-4484-2023-42-46" @default.
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