FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4360839105> ?p ?o ?g. }

• W4360839105 endingPage "328222" @default.
• W4360839105 startingPage "gutjnl" @default.
• W4360839105 abstract "We aimed to compare the response rates between two different hepatitis B virus vaccination schedules for cirrhotic subjects who were non-responders to the first three 40 µg doses (month 0-1-2), and identify factors associated with the final response.A total of 120 cirrhotic patients (72.5% decompensated) were randomised at a 1:1 ratio to receive a single 40 µg booster vaccination at month 6 (classical arm) versus an additional round of three new 40 µg doses administered at monthly intervals (experimental arm). The main outcome was the rate of postvaccinal anti-hepatitis B surface antibodies levels ≥10 mIU/mL.Efficacy by ITT analysis was higher in the experimental arm (46.7%) than in the classical one (25%); OR 2.63, p=0.013. The experimental arm increased response rates compared with the classical one from 31% to 68% (OR 4.72; p=0.007), from 24.4% to 50% (OR 3.09; p=0.012) and from 24.4% to 53.8% (OR 3.62; p=0.007), in Child A, Model for End-Stage Liver Disease (MELD) <15 and MELD-Na<15 patients, respectively. Patients with more advanced liver disease did not benefit from the reinforced scheme. Both regimens showed similar safety profiles. Multivariable analysis showed that the experimental treatment was independently response associated when adjusted across three logistic regression models indicating equivalent cirrhosis severity.For cirrhotic patients, the revaccination of non-responders to the first three dose cycle, with three additional 40 µg doses, achieved significantly better response rates to those obtained with an isolated 40 µg booster dose.NCT01884415." @default.
• W4360839105 created "2023-03-25" @default.
• W4360839105 creator A5005763237 @default.
• W4360839105 creator A5010866071 @default.
• W4360839105 creator A5016975124 @default.
• W4360839105 creator A5023564781 @default.
• W4360839105 creator A5024617098 @default.
• W4360839105 creator A5028980383 @default.
• W4360839105 creator A5040435679 @default.
• W4360839105 creator A5057346237 @default.
• W4360839105 creator A5066851747 @default.
• W4360839105 creator A5067070873 @default.
• W4360839105 creator A5068832578 @default.
• W4360839105 creator A5071764114 @default.
• W4360839105 creator A5073540287 @default.
• W4360839105 creator A5075893741 @default.
• W4360839105 creator A5080312926 @default.
• W4360839105 creator A5081975863 @default.
• W4360839105 creator A5083797541 @default.
• W4360839105 date "2023-03-24" @default.
• W4360839105 modified "2023-10-01" @default.
• W4360839105 title "Three double-dose reinforced hepatitis B revaccination scheme for patients with cirrhosis unresponsive to the standard regimen: an open-label randomised clinical trial" @default.
• W4360839105 cites W1517910709 @default.
• W4360839105 cites W1806743205 @default.
• W4360839105 cites W1983557513 @default.
• W4360839105 cites W1992424184 @default.
• W4360839105 cites W2007354162 @default.
• W4360839105 cites W2028658507 @default.
• W4360839105 cites W2043300136 @default.
• W4360839105 cites W2044246489 @default.
• W4360839105 cites W2068204482 @default.
• W4360839105 cites W2071557486 @default.
• W4360839105 cites W2084361316 @default.
• W4360839105 cites W2090371275 @default.
• W4360839105 cites W2092264123 @default.
• W4360839105 cites W2115705306 @default.
• W4360839105 cites W2117625373 @default.
• W4360839105 cites W2135716906 @default.
• W4360839105 cites W2160544967 @default.
• W4360839105 cites W2365770820 @default.
• W4360839105 cites W2748400966 @default.
• W4360839105 cites W2756245994 @default.
• W4360839105 cites W2787738374 @default.
• W4360839105 cites W2791839818 @default.
• W4360839105 cites W2883388650 @default.
• W4360839105 cites W2917871838 @default.
• W4360839105 cites W2921553057 @default.
• W4360839105 cites W2973214315 @default.
• W4360839105 cites W3111489061 @default.
• W4360839105 cites W3139121454 @default.
• W4360839105 cites W3193967241 @default.
• W4360839105 cites W4237427832 @default.
• W4360839105 cites W4237472114 @default.
• W4360839105 cites W4327849090 @default.
• W4360839105 cites W71557436 @default.
• W4360839105 doi "https://doi.org/10.1136/gutjnl-2022-328222" @default.
• W4360839105 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36963815" @default.
• W4360839105 hasPublicationYear "2023" @default.
• W4360839105 type Work @default.
• W4360839105 citedByCount "1" @default.
• W4360839105 countsByYear W43608391052023 @default.
• W4360839105 crossrefType "journal-article" @default.
• W4360839105 hasAuthorship W4360839105A5005763237 @default.
• W4360839105 hasAuthorship W4360839105A5010866071 @default.
• W4360839105 hasAuthorship W4360839105A5016975124 @default.
• W4360839105 hasAuthorship W4360839105A5023564781 @default.
• W4360839105 hasAuthorship W4360839105A5024617098 @default.
• W4360839105 hasAuthorship W4360839105A5028980383 @default.
• W4360839105 hasAuthorship W4360839105A5040435679 @default.
• W4360839105 hasAuthorship W4360839105A5057346237 @default.
• W4360839105 hasAuthorship W4360839105A5066851747 @default.
• W4360839105 hasAuthorship W4360839105A5067070873 @default.
• W4360839105 hasAuthorship W4360839105A5068832578 @default.
• W4360839105 hasAuthorship W4360839105A5071764114 @default.
• W4360839105 hasAuthorship W4360839105A5073540287 @default.
• W4360839105 hasAuthorship W4360839105A5075893741 @default.
• W4360839105 hasAuthorship W4360839105A5080312926 @default.
• W4360839105 hasAuthorship W4360839105A5081975863 @default.
• W4360839105 hasAuthorship W4360839105A5083797541 @default.
• W4360839105 hasConcept C126322002 @default.
• W4360839105 hasConcept C141071460 @default.
• W4360839105 hasConcept C203014093 @default.
• W4360839105 hasConcept C2522874641 @default.
• W4360839105 hasConcept C2777075537 @default.
• W4360839105 hasConcept C2777214474 @default.
• W4360839105 hasConcept C2777382497 @default.
• W4360839105 hasConcept C2780593183 @default.
• W4360839105 hasConcept C2781413609 @default.
• W4360839105 hasConcept C44249647 @default.
• W4360839105 hasConcept C71924100 @default.
• W4360839105 hasConcept C90924648 @default.
• W4360839105 hasConceptScore W4360839105C126322002 @default.
• W4360839105 hasConceptScore W4360839105C141071460 @default.
• W4360839105 hasConceptScore W4360839105C203014093 @default.
• W4360839105 hasConceptScore W4360839105C2522874641 @default.
• W4360839105 hasConceptScore W4360839105C2777075537 @default.
• W4360839105 hasConceptScore W4360839105C2777214474 @default.
• W4360839105 hasConceptScore W4360839105C2777382497 @default.

• next