Matches in SemOpenAlex for { <https://semopenalex.org/work/W4360860151> ?p ?o ?g. }
- W4360860151 endingPage "6096" @default.
- W4360860151 startingPage "6096" @default.
- W4360860151 abstract "Neuropeptide B (NPB) affects energy homeostasis and metabolism by binding and activating NPBWR1 and NPBWR2 in humans and pigs. Recently, we reported that NPB promotes the adipogenesis of rat white and brown preadipocytes as well as 3T3-L1 cells. In the present study, we evaluated the effects of NPB on the proliferation and differentiation of white porcine preadipocytes into mature adipocytes. We identified the presence of NPB, NPBWR1, and NPBWR2 on the mRNA and protein levels in porcine white preadipocytes. During the differentiation process, NPB increased the mRNA expression of PPARγ, C/EBPβ, C/EBPα, PPARγ, and C/EBPβ protein production in porcine preadipocytes. Furthermore, NPB stimulated lipid accumulation in porcine preadipocytes. Moreover, NPB promoted the phosphorylation of the p38 kinase in porcine preadipocytes, but failed to induce ERK1/2 phosphorylation. NPB failed to stimulate the expression of C/EBPβ in the presence of the p38 inhibitor. Taken together, we report that NPB promotes the differentiation of porcine preadipocytes via a p38-dependent mechanism." @default.
- W4360860151 created "2023-03-25" @default.
- W4360860151 creator A5062063876 @default.
- W4360860151 creator A5065126821 @default.
- W4360860151 creator A5068093546 @default.
- W4360860151 creator A5074676016 @default.
- W4360860151 creator A5080827425 @default.
- W4360860151 creator A5087160874 @default.
- W4360860151 date "2023-03-23" @default.
- W4360860151 modified "2023-10-17" @default.
- W4360860151 title "The Effects of Neuropeptide B on Proliferation and Differentiation of Porcine White Preadipocytes into Mature Adipocytes" @default.
- W4360860151 cites W1487090175 @default.
- W4360860151 cites W1540974041 @default.
- W4360860151 cites W1574063311 @default.
- W4360860151 cites W1907219612 @default.
- W4360860151 cites W1968402870 @default.
- W4360860151 cites W1974387131 @default.
- W4360860151 cites W1974648670 @default.
- W4360860151 cites W1987120082 @default.
- W4360860151 cites W1990468252 @default.
- W4360860151 cites W1996356699 @default.
- W4360860151 cites W2005856326 @default.
- W4360860151 cites W2007986629 @default.
- W4360860151 cites W2014134228 @default.
- W4360860151 cites W2033392856 @default.
- W4360860151 cites W2060978273 @default.
- W4360860151 cites W2061046384 @default.
- W4360860151 cites W2061967227 @default.
- W4360860151 cites W2063840236 @default.
- W4360860151 cites W2067497187 @default.
- W4360860151 cites W2091164627 @default.
- W4360860151 cites W2096000142 @default.
- W4360860151 cites W2098756310 @default.
- W4360860151 cites W2102313291 @default.
- W4360860151 cites W2102575016 @default.
- W4360860151 cites W2106668767 @default.
- W4360860151 cites W2107495112 @default.
- W4360860151 cites W2119229647 @default.
- W4360860151 cites W2139823456 @default.
- W4360860151 cites W2144720369 @default.
- W4360860151 cites W2150621637 @default.
- W4360860151 cites W2156877200 @default.
- W4360860151 cites W21713698 @default.
- W4360860151 cites W2284659436 @default.
- W4360860151 cites W2402544605 @default.
- W4360860151 cites W2462580104 @default.
- W4360860151 cites W2520995681 @default.
- W4360860151 cites W2789614973 @default.
- W4360860151 cites W2905558963 @default.
- W4360860151 cites W2945125308 @default.
- W4360860151 cites W2952771829 @default.
- W4360860151 cites W2966612223 @default.
- W4360860151 cites W3037564779 @default.
- W4360860151 cites W3094071743 @default.
- W4360860151 cites W3094552695 @default.
- W4360860151 cites W3116144282 @default.
- W4360860151 cites W3125011350 @default.
- W4360860151 cites W3131496441 @default.
- W4360860151 cites W3157654347 @default.
- W4360860151 cites W343065178 @default.
- W4360860151 cites W34404506 @default.
- W4360860151 cites W4308462480 @default.
- W4360860151 cites W4313644999 @default.
- W4360860151 cites W895576401 @default.
- W4360860151 cites W2523938531 @default.
- W4360860151 doi "https://doi.org/10.3390/ijms24076096" @default.
- W4360860151 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37047072" @default.
- W4360860151 hasPublicationYear "2023" @default.
- W4360860151 type Work @default.
- W4360860151 citedByCount "0" @default.
- W4360860151 crossrefType "journal-article" @default.
- W4360860151 hasAuthorship W4360860151A5062063876 @default.
- W4360860151 hasAuthorship W4360860151A5065126821 @default.
- W4360860151 hasAuthorship W4360860151A5068093546 @default.
- W4360860151 hasAuthorship W4360860151A5074676016 @default.
- W4360860151 hasAuthorship W4360860151A5080827425 @default.
- W4360860151 hasAuthorship W4360860151A5087160874 @default.
- W4360860151 hasBestOaLocation W43608601511 @default.
- W4360860151 hasConcept C104317684 @default.
- W4360860151 hasConcept C105580179 @default.
- W4360860151 hasConcept C11960822 @default.
- W4360860151 hasConcept C122927707 @default.
- W4360860151 hasConcept C126322002 @default.
- W4360860151 hasConcept C134018914 @default.
- W4360860151 hasConcept C171089720 @default.
- W4360860151 hasConcept C184235292 @default.
- W4360860151 hasConcept C185592680 @default.
- W4360860151 hasConcept C51551487 @default.
- W4360860151 hasConcept C55493867 @default.
- W4360860151 hasConcept C71924100 @default.
- W4360860151 hasConcept C86803240 @default.
- W4360860151 hasConcept C95444343 @default.
- W4360860151 hasConcept C97029542 @default.
- W4360860151 hasConceptScore W4360860151C104317684 @default.
- W4360860151 hasConceptScore W4360860151C105580179 @default.
- W4360860151 hasConceptScore W4360860151C11960822 @default.
- W4360860151 hasConceptScore W4360860151C122927707 @default.
- W4360860151 hasConceptScore W4360860151C126322002 @default.