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- W4360969772 abstract "Globally, alcohol-induced liver damage is an important issue and is pathologically manifested as fatty liver, alcoholic hepatitis, alcoholic cirrhosis, and hepatocellular carcinoma in the long-term users. Although the mechanisms underlying alcohol-related carcinogenesis are unknown, most research has concentrated on acetaldehyde, the highly lethal ethanol metabolite, as a cancer-causing agent. Free radical generation, epigenetic regulation, gut microbiota modulation nutrition, genetic predisposition, and immunological regulation, in addition to alcohol metabolism, have all been linked to the development of hepatocellular carcinoma in recent studies. Probiotics have been shown in recent scientific investigations to be important in reducing alcohol-induced hepatic damage and cancer. Furthermore, studies have indicated that probiotics, both alone and in combination with glutamine, vitamin C, and green tea extract, are effective in reducing damage. This review will examine these issues for the first time. The goal of this review is to look into the liver-related health benefits of prebiotics and synbiotics, with a focus on their specific implications in the human gut." @default.
- W4360969772 created "2023-03-30" @default.
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- W4360969772 date "2023-01-01" @default.
- W4360969772 modified "2023-09-26" @default.
- W4360969772 title "Role of Probiotics and Synbiotics in Mitigating Alcohol-Induced Liver Damage" @default.
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- W4360969772 doi "https://doi.org/10.1007/978-981-19-7550-9_16" @default.
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