Matches in SemOpenAlex for { <https://semopenalex.org/work/W4360975737> ?p ?o ?g. }
- W4360975737 endingPage "52" @default.
- W4360975737 startingPage "46" @default.
- W4360975737 abstract "Chinese officials have reported the novel coronavirus to the world health organization, which is called the SARS-CoV-2. Toll-like receptor 3 (TLR3) induces antiviral immune responses via the production of type I interferons and inflammatory cytokines. In this study, we aimed to examine TLR3 c.1377C/T and -7C/A polymorphisms in COVID-19 and the association between some clinical parameters. We investigated the frequencies of TLR3 (c.1377C/T and -7C/A) polymorphisms in 150 patients with COVID-19 and 171 healthy individuals as controls. We performed polymerase chain reaction (PCR) based on restriction fragment length polymorphism (RFLP). We also investigated whether TLR3 c.1377C/T and-7C/A were associated with the severity of COVID-19. In addition, CHAID tree-based classification algorithm was created to investigate the severity of the patients in our study. TLR3 c.1377C/T TT genotype frequencies were statistically significant between cases and controls (p= 0.02). For TLR3 -7C/A polymorphism, the findings showed a statistically significant difference in A allele frequencies (p= 0.03). There was a statistically significant difference in the distribution of TLR3 -7C/A CA genotype frequency (p= 0.04). Our findings suggest that TLR3 c.1377C/T and -7C/A polymorphisms may be important on susceptibility or clinical course of COVID-19." @default.
- W4360975737 created "2023-03-30" @default.
- W4360975737 creator A5018940905 @default.
- W4360975737 creator A5019602804 @default.
- W4360975737 creator A5044145863 @default.
- W4360975737 creator A5045360160 @default.
- W4360975737 creator A5048519122 @default.
- W4360975737 date "2023-03-26" @default.
- W4360975737 modified "2023-10-14" @default.
- W4360975737 title "Toll-like Receptor 3 c.1377C/T and -7C/A Polymorphisms Associated with COVID-19 and COVID-19 Severity" @default.
- W4360975737 cites W1995744610 @default.
- W4360975737 cites W2056056969 @default.
- W4360975737 cites W2077550407 @default.
- W4360975737 cites W2083808530 @default.
- W4360975737 cites W2094045593 @default.
- W4360975737 cites W2101363646 @default.
- W4360975737 cites W2109445380 @default.
- W4360975737 cites W2109491705 @default.
- W4360975737 cites W2144652247 @default.
- W4360975737 cites W2287500273 @default.
- W4360975737 cites W2295259402 @default.
- W4360975737 cites W2575102064 @default.
- W4360975737 cites W2612145263 @default.
- W4360975737 cites W2896276705 @default.
- W4360975737 cites W2903899730 @default.
- W4360975737 cites W2926616919 @default.
- W4360975737 cites W2947604924 @default.
- W4360975737 cites W3001456238 @default.
- W4360975737 cites W3002659854 @default.
- W4360975737 cites W3004280078 @default.
- W4360975737 cites W3004348779 @default.
- W4360975737 cites W3009692671 @default.
- W4360975737 cites W3009849619 @default.
- W4360975737 cites W3009906937 @default.
- W4360975737 cites W3014207782 @default.
- W4360975737 cites W3020305053 @default.
- W4360975737 cites W3037408845 @default.
- W4360975737 cites W3080591447 @default.
- W4360975737 cites W3084909506 @default.
- W4360975737 cites W3094988199 @default.
- W4360975737 cites W3121286637 @default.
- W4360975737 cites W402779438 @default.
- W4360975737 cites W4205695596 @default.
- W4360975737 doi "https://doi.org/10.17776/csj.1167703" @default.
- W4360975737 hasPublicationYear "2023" @default.
- W4360975737 type Work @default.
- W4360975737 citedByCount "0" @default.
- W4360975737 crossrefType "journal-article" @default.
- W4360975737 hasAuthorship W4360975737A5018940905 @default.
- W4360975737 hasAuthorship W4360975737A5019602804 @default.
- W4360975737 hasAuthorship W4360975737A5044145863 @default.
- W4360975737 hasAuthorship W4360975737A5045360160 @default.
- W4360975737 hasAuthorship W4360975737A5048519122 @default.
- W4360975737 hasBestOaLocation W43609757371 @default.
- W4360975737 hasConcept C104317684 @default.
- W4360975737 hasConcept C126322002 @default.
- W4360975737 hasConcept C135763542 @default.
- W4360975737 hasConcept C136449434 @default.
- W4360975737 hasConcept C159047783 @default.
- W4360975737 hasConcept C168007829 @default.
- W4360975737 hasConcept C170493617 @default.
- W4360975737 hasConcept C203014093 @default.
- W4360975737 hasConcept C2776709828 @default.
- W4360975737 hasConcept C2778420691 @default.
- W4360975737 hasConcept C2779134260 @default.
- W4360975737 hasConcept C3008058167 @default.
- W4360975737 hasConcept C524204448 @default.
- W4360975737 hasConcept C54355233 @default.
- W4360975737 hasConcept C71924100 @default.
- W4360975737 hasConcept C86803240 @default.
- W4360975737 hasConcept C8891405 @default.
- W4360975737 hasConceptScore W4360975737C104317684 @default.
- W4360975737 hasConceptScore W4360975737C126322002 @default.
- W4360975737 hasConceptScore W4360975737C135763542 @default.
- W4360975737 hasConceptScore W4360975737C136449434 @default.
- W4360975737 hasConceptScore W4360975737C159047783 @default.
- W4360975737 hasConceptScore W4360975737C168007829 @default.
- W4360975737 hasConceptScore W4360975737C170493617 @default.
- W4360975737 hasConceptScore W4360975737C203014093 @default.
- W4360975737 hasConceptScore W4360975737C2776709828 @default.
- W4360975737 hasConceptScore W4360975737C2778420691 @default.
- W4360975737 hasConceptScore W4360975737C2779134260 @default.
- W4360975737 hasConceptScore W4360975737C3008058167 @default.
- W4360975737 hasConceptScore W4360975737C524204448 @default.
- W4360975737 hasConceptScore W4360975737C54355233 @default.
- W4360975737 hasConceptScore W4360975737C71924100 @default.
- W4360975737 hasConceptScore W4360975737C86803240 @default.
- W4360975737 hasConceptScore W4360975737C8891405 @default.
- W4360975737 hasIssue "1" @default.
- W4360975737 hasLocation W43609757371 @default.
- W4360975737 hasLocation W43609757372 @default.
- W4360975737 hasOpenAccess W4360975737 @default.
- W4360975737 hasPrimaryLocation W43609757371 @default.
- W4360975737 hasRelatedWork W1964389499 @default.
- W4360975737 hasRelatedWork W2008583571 @default.
- W4360975737 hasRelatedWork W2042544550 @default.
- W4360975737 hasRelatedWork W2060550909 @default.
- W4360975737 hasRelatedWork W2062987859 @default.