FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4360984901> ?p ?o ?g. }

• W4360984901 abstract "A label-free electrogenerated chemiluminescence (ECL) aptasensing method for highly sensitive determination of dopamine (DA) was developed based on target-induced DNA conformational change. After anti-DA specific aptamer, as molecular recognition element, was hybridized with a capture ss-DNA (complementary with the aptamer), the formed double-strand DNA (ds-DNA) was self-assembled onto the surface of a gold electrode, and then Ru(phen)32+, as ECL reagent, was intercalated into ds-DNA to form an ECL biosensing platform. In the presence of DA, DA bound with its aptamer and target-induced DNA conformational change occurred, resulting in the dissociation of ds-DNA, the release of intercalated Ru(phen)32+ from the electrode surface, and the decrease of ECL intensity. For comparison, an ECL aptamer-based biosensing method using an ECL reagent-labeled aptamer was also developed for DA assay based on target-induced DNA conformational change. Because of the increase in the amount of ECL reagent into ds-DNA over that of the single-site ECL reagent-labeled aptamer, an obvious increase of ECL intensity was found at the ds-DNA modified electrode over the aptamer modified electrode. DA can be sensitively detected with a lower detection limit of 0.05 nM in the range from 0.1 to 100 nM. With the recognition of the aptamer for DA, DA can be selectively and sensitively detected in artificial cerebrospinal fluid and serum samples without interference from common small molecules. This work demonstrates that the combination of the direct transduction of specific recognition of DA and its aptamer into an ECL signal with Ru(phen)32+ intercalated ds-DNA amplification provides a promising strategy for the development of a simple, sensitive, and selective method for DA assay, which is of great importance in neurochemical assays and clinical diagnosis." @default.
• W4360984901 created "2023-03-30" @default.
• W4360984901 creator A5014790362 @default.
• W4360984901 creator A5019606817 @default.
• W4360984901 creator A5046141530 @default.
• W4360984901 creator A5068187238 @default.
• W4360984901 creator A5069181363 @default.
• W4360984901 creator A5089654039 @default.
• W4360984901 date "2023-03-26" @default.
• W4360984901 modified "2023-10-16" @default.
• W4360984901 title "Label-Free Electrogenerated Chemiluminescence Aptasensing Method for Highly Sensitive Determination of Dopamine via Target-Induced DNA Conformational Change" @default.
• W4360984901 cites W1546116904 @default.
• W4360984901 cites W1896803895 @default.
• W4360984901 cites W1965736450 @default.
• W4360984901 cites W1994014422 @default.
• W4360984901 cites W2002755272 @default.
• W4360984901 cites W2009818318 @default.
• W4360984901 cites W2014562079 @default.
• W4360984901 cites W2017132242 @default.
• W4360984901 cites W2020092710 @default.
• W4360984901 cites W2067083366 @default.
• W4360984901 cites W2079329107 @default.
• W4360984901 cites W2087661789 @default.
• W4360984901 cites W2088259422 @default.
• W4360984901 cites W2139851375 @default.
• W4360984901 cites W2161756416 @default.
• W4360984901 cites W2313321523 @default.
• W4360984901 cites W2314104404 @default.
• W4360984901 cites W2345480321 @default.
• W4360984901 cites W2617844356 @default.
• W4360984901 cites W2760396837 @default.
• W4360984901 cites W2768170393 @default.
• W4360984901 cites W2891599654 @default.
• W4360984901 cites W2906854319 @default.
• W4360984901 cites W2909636450 @default.
• W4360984901 cites W2992158209 @default.
• W4360984901 cites W2999737396 @default.
• W4360984901 cites W3004004141 @default.
• W4360984901 cites W3033639276 @default.
• W4360984901 cites W3034066537 @default.
• W4360984901 cites W3034299812 @default.
• W4360984901 cites W3041949755 @default.
• W4360984901 cites W3043664694 @default.
• W4360984901 cites W3095116189 @default.
• W4360984901 cites W3144730627 @default.
• W4360984901 cites W4224884103 @default.
• W4360984901 cites W4224982800 @default.
• W4360984901 cites W4225851984 @default.
• W4360984901 cites W4303699576 @default.
• W4360984901 cites W4310733198 @default.
• W4360984901 doi "https://doi.org/10.1021/acs.analchem.3c00113" @default.
• W4360984901 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36967489" @default.
• W4360984901 hasPublicationYear "2023" @default.
• W4360984901 type Work @default.
• W4360984901 citedByCount "0" @default.
• W4360984901 crossrefType "journal-article" @default.
• W4360984901 hasAuthorship W4360984901A5014790362 @default.
• W4360984901 hasAuthorship W4360984901A5019606817 @default.
• W4360984901 hasAuthorship W4360984901A5046141530 @default.
• W4360984901 hasAuthorship W4360984901A5068187238 @default.
• W4360984901 hasAuthorship W4360984901A5069181363 @default.
• W4360984901 hasAuthorship W4360984901A5089654039 @default.
• W4360984901 hasConcept C119128265 @default.
• W4360984901 hasConcept C128972844 @default.
• W4360984901 hasConcept C145802702 @default.
• W4360984901 hasConcept C147789679 @default.
• W4360984901 hasConcept C153911025 @default.
• W4360984901 hasConcept C160756335 @default.
• W4360984901 hasConcept C17525397 @default.
• W4360984901 hasConcept C178790620 @default.
• W4360984901 hasConcept C185592680 @default.
• W4360984901 hasConcept C191961535 @default.
• W4360984901 hasConcept C21951064 @default.
• W4360984901 hasConcept C38965407 @default.
• W4360984901 hasConcept C40875361 @default.
• W4360984901 hasConcept C43617362 @default.
• W4360984901 hasConcept C552990157 @default.
• W4360984901 hasConcept C55493867 @default.
• W4360984901 hasConcept C86803240 @default.
• W4360984901 hasConceptScore W4360984901C119128265 @default.
• W4360984901 hasConceptScore W4360984901C128972844 @default.
• W4360984901 hasConceptScore W4360984901C145802702 @default.
• W4360984901 hasConceptScore W4360984901C147789679 @default.
• W4360984901 hasConceptScore W4360984901C153911025 @default.
• W4360984901 hasConceptScore W4360984901C160756335 @default.
• W4360984901 hasConceptScore W4360984901C17525397 @default.
• W4360984901 hasConceptScore W4360984901C178790620 @default.
• W4360984901 hasConceptScore W4360984901C185592680 @default.
• W4360984901 hasConceptScore W4360984901C191961535 @default.
• W4360984901 hasConceptScore W4360984901C21951064 @default.
• W4360984901 hasConceptScore W4360984901C38965407 @default.
• W4360984901 hasConceptScore W4360984901C40875361 @default.
• W4360984901 hasConceptScore W4360984901C43617362 @default.
• W4360984901 hasConceptScore W4360984901C552990157 @default.
• W4360984901 hasConceptScore W4360984901C55493867 @default.
• W4360984901 hasConceptScore W4360984901C86803240 @default.
• W4360984901 hasFunder F4320321001 @default.
• W4360984901 hasFunder F4320329878 @default.
• W4360984901 hasLocation W43609849011 @default.
• W4360984901 hasLocation W43609849012 @default.

• next