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- W4360984973 abstract "Abstract To reduce the use of antibiotics, research into nutritional strategies designed to improve the gut health of weaned pigs are underway. This study sought to examine the effects of reducing dietary crude protein (CP) and/or supplementing the feed with sodium butyrate protected by the sodium salts of medium-chain fatty acids on the growth performance and gut health of weaned piglets. Ninety-six weaned piglets (Landrace x Large White, 21 days of age) were allotted to four experimental treatments for 14 days. The experimental design was factorial with 2 CP levels and 2 feed-additive doses (0 vs 1 kg/t). Results showed that reducing CP from 22.2 to 18.8% diet had no effect on piglet growth performance parameters during the first post-weaning week (P > 0.05), but did compromise growth in the second week (P = 0.011), impacting on overall growth performance results (P = 0.019). Nonetheless, dietary CP level reduction led to reduce crypt depth (P = 0.036). In addition, Lactobacillus counts that were increased in the ileum (P = 0.032) and reduced in the colon (P = 0.032). Furthermore, apparent ileal digestibility of organic matter (P = 0.026) and fecal consistency (P < 0.05) were improved throughout the experiment. Moreover, in piglets fed diets containing 22.2% CP, the use of the feed-additive tended to improve the gain-to-feed ratio (P = 0.091) compared to those fed supplemented diets containing 18.8% CP. In addition, feed supplementation increased ileal numbers of goblet cells (P = 0.036), as well as apparent ileal digestibility of dry matter (P = 0.057) and organic matter (P = 0.003). Supplementation also had beneficial effects on the microbiota of the colon, increasing Lactobacillus counts (P = 0.006) and diminishing Enterobacteriaceae counts (P = 0.003), as well as affecting microbial metabolite profiles in that acetic acid concentrations tended to be increased (P = 0.088) and valeric acid concentrations were reduced (P = 0.002). These findings support the use of both strategies can improve the gut health of weaned piglets and prompt further research into the possible benefits of combining these two nutritional strategies on gut health and growth performance." @default.
- W4360984973 created "2023-03-30" @default.
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- W4360984973 date "2023-03-27" @default.
- W4360984973 modified "2023-10-16" @default.
- W4360984973 title "Effects of dietary crude protein level and sodium butyrate protected by medium-chain fatty acid salts on performance and gut health in weaned piglets" @default.
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- W4360984973 doi "https://doi.org/10.1093/jas/skad090" @default.
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