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- W4360993734 abstract "Abstract In recent years, the development of hyaluronic acid or hyaluronan (HA) based scaffolds, medical devices, bioconjugate systems have expanded into a broad range of research and clinical applications. Research findings over the last two decades suggest that the abundance of HA in most mammalian tissues with distinctive biological roles and chemical simplicity for modifications have made it an attractive material with a rapidly growing global market. Besides its use as native forms, HA has received much interest on so‐called “HA‐bioconjugates” and “modified‐HA systems”. In this review, the importance of chemical modifications of HA, underlying rationale approaches, and various advancements of bioconjugate derivatives with their potential physicochemical, and pharmacological advantages are summarized. This review also highlights the current and emerging HA‐based conjugates of small molecules, macromolecules, crosslinked systems, and surface coating strategies with their biological implications, including their potentials and key challenges discussed in detail." @default.
- W4360993734 created "2023-03-30" @default.
- W4360993734 creator A5002167350 @default.
- W4360993734 creator A5042223305 @default.
- W4360993734 creator A5049916581 @default.
- W4360993734 creator A5058217051 @default.
- W4360993734 creator A5068986887 @default.
- W4360993734 creator A5069235915 @default.
- W4360993734 creator A5082501900 @default.
- W4360993734 date "2023-04-16" @default.
- W4360993734 modified "2023-10-03" @default.
- W4360993734 title "Hyaluronic Acid‐Based Bioconjugate Systems, Scaffolds, and Their Therapeutic Potential" @default.
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