Matches in SemOpenAlex for { <https://semopenalex.org/work/W4361005384> ?p ?o ?g. }
Showing items 1 to 77 of
77
with 100 items per page.
- W4361005384 endingPage "32" @default.
- W4361005384 startingPage "25" @default.
- W4361005384 abstract "Background. Given the role of hormones in the regulation of scar formation and remodeling processes, it is advisable to study the features of the hormonal profile in conditions of pathological scars. This will improve the efficiency of diagnosing of scar type and form a pathogenetic basis for the treatment of hypertrophic and keloid scars. Aim. To identify the features of the hormonal profile in conditions of hypertrophic and keloid scars. Materials and methods. The clinical state of the scars and the hormonal profile (10 hormones) were studied in 90 women with hypertrophic, keloid and normotrophic scars (control). Blood was taken before treatment on the 5th–7th day of the menstrual cycle. The results were processed by non-parametric statistics (Me (Q25-Q75), U-test at p<0.05). Correlations between hormones were determined by the method of multiple regression at the coefficient of determination R2>0.7. Results. All patients with pathological scars showed a decrease in cortisol levels. Hypertrophic scars are characterized by an increase in the concentration of follicle-stimulating hormone, a decrease in the concentration of estradiol and testosterone. In patients with keloids, the concentration of growth hormone is increased, the levels of prolactin, luteinizing hormone are reduced. Regression analysis showed that the interdependence of hormones is maximally expressed in conditions of normotrophic scars, while hormones had 1-2 correlations in conditions of pathological scars. At the same time, the qualitative composition and direction of interrelations have changed. Conclusion. Pathological scarring is characterized by a decrease in the level of cortisol in the blood, which is expressed in patients with keloid scars in combination with reduced prolactin. A weakening of hormonal interactions and an imbalance in the system of sex hormones were revealed in conditions of hypertrophic scars. and the increased production of growth hormone in combination with a stable interaction between steroidogenesis and a weakened adaptive ability took place in conditions of keloid scars." @default.
- W4361005384 created "2023-03-30" @default.
- W4361005384 creator A5066638675 @default.
- W4361005384 date "2023-03-10" @default.
- W4361005384 modified "2023-10-16" @default.
- W4361005384 title "FEATURES OF ENDOCRINE PROFILE IN HYPERTROPHIC AND KELOID SCARS OF SKIN" @default.
- W4361005384 cites W1969259869 @default.
- W4361005384 cites W1971179316 @default.
- W4361005384 cites W1973361468 @default.
- W4361005384 cites W1973747060 @default.
- W4361005384 cites W2050391209 @default.
- W4361005384 cites W2052534485 @default.
- W4361005384 cites W2069360747 @default.
- W4361005384 cites W2093777114 @default.
- W4361005384 cites W2155514122 @default.
- W4361005384 cites W2765643716 @default.
- W4361005384 cites W2890928025 @default.
- W4361005384 cites W2902300236 @default.
- W4361005384 cites W2903464283 @default.
- W4361005384 cites W3082800191 @default.
- W4361005384 doi "https://doi.org/10.57256/2949-0715-2023-1-25-32" @default.
- W4361005384 hasPublicationYear "2023" @default.
- W4361005384 type Work @default.
- W4361005384 citedByCount "0" @default.
- W4361005384 crossrefType "journal-article" @default.
- W4361005384 hasAuthorship W4361005384A5066638675 @default.
- W4361005384 hasBestOaLocation W43610053841 @default.
- W4361005384 hasConcept C126322002 @default.
- W4361005384 hasConcept C134018914 @default.
- W4361005384 hasConcept C142724271 @default.
- W4361005384 hasConcept C16005928 @default.
- W4361005384 hasConcept C207886595 @default.
- W4361005384 hasConcept C2777538232 @default.
- W4361005384 hasConcept C2777642821 @default.
- W4361005384 hasConcept C2778575703 @default.
- W4361005384 hasConcept C2778698245 @default.
- W4361005384 hasConcept C2779064019 @default.
- W4361005384 hasConcept C2779279991 @default.
- W4361005384 hasConcept C3019227704 @default.
- W4361005384 hasConcept C46699223 @default.
- W4361005384 hasConcept C71315377 @default.
- W4361005384 hasConcept C71924100 @default.
- W4361005384 hasConceptScore W4361005384C126322002 @default.
- W4361005384 hasConceptScore W4361005384C134018914 @default.
- W4361005384 hasConceptScore W4361005384C142724271 @default.
- W4361005384 hasConceptScore W4361005384C16005928 @default.
- W4361005384 hasConceptScore W4361005384C207886595 @default.
- W4361005384 hasConceptScore W4361005384C2777538232 @default.
- W4361005384 hasConceptScore W4361005384C2777642821 @default.
- W4361005384 hasConceptScore W4361005384C2778575703 @default.
- W4361005384 hasConceptScore W4361005384C2778698245 @default.
- W4361005384 hasConceptScore W4361005384C2779064019 @default.
- W4361005384 hasConceptScore W4361005384C2779279991 @default.
- W4361005384 hasConceptScore W4361005384C3019227704 @default.
- W4361005384 hasConceptScore W4361005384C46699223 @default.
- W4361005384 hasConceptScore W4361005384C71315377 @default.
- W4361005384 hasConceptScore W4361005384C71924100 @default.
- W4361005384 hasIssue "1" @default.
- W4361005384 hasLocation W43610053841 @default.
- W4361005384 hasOpenAccess W4361005384 @default.
- W4361005384 hasPrimaryLocation W43610053841 @default.
- W4361005384 hasRelatedWork W1976876172 @default.
- W4361005384 hasRelatedWork W1988486434 @default.
- W4361005384 hasRelatedWork W1994104316 @default.
- W4361005384 hasRelatedWork W2047880909 @default.
- W4361005384 hasRelatedWork W2100202028 @default.
- W4361005384 hasRelatedWork W2116061575 @default.
- W4361005384 hasRelatedWork W2349566392 @default.
- W4361005384 hasRelatedWork W2378249791 @default.
- W4361005384 hasRelatedWork W2391654246 @default.
- W4361005384 hasRelatedWork W2991162479 @default.
- W4361005384 hasVolume "2" @default.
- W4361005384 isParatext "false" @default.
- W4361005384 isRetracted "false" @default.
- W4361005384 workType "article" @default.