Matches in SemOpenAlex for { <https://semopenalex.org/work/W4361010802> ?p ?o ?g. }
- W4361010802 endingPage "1014" @default.
- W4361010802 startingPage "1014" @default.
- W4361010802 abstract "This study investigated the effect of low-intensity blue light on the albino Wistar rat retina, including intrinsically photosensitive retinal ganglion cells (ipRGCs). Three groups of nine albino Wistar rats were used. One group was continuously exposed to blue light (150 lx) for 2 d (STE); one was exposed to 12 h of blue light and 12 h of darkness for 10 d (LTE); one was maintained in 12 h of white light (150 lx) and 12 h of darkness for 10 d (control). Melanopsin (Opn4) was immunolabelled on retinal whole-mounts. To count and measure Opn4-positive ipRGC somas and dendrites (including Sholl profiles), Neuron J was used. Retinal cryosections were immunolabeled for glial fibrillary acid protein (GFAP) and with terminal deoxynucleotidyl transferase dUTP nick-end labelling for apoptosis detection. LTE reduced the length of Opn4-positive ipRGC dendrites (p = 0.03) and decreased Opn4-immunoreactivity in ipRGC outer stratifying dendrites. LTE and STE decreased the complexity of dendritic arborization (Sholl profile; p < 0.001, p = 0.03, respectively), increased retinal GFAP immunoreactivity (p < 0.001, p = 0.002, respectively), and caused outer segment vesiculation and outer nuclear layer apoptosis. Ultrastructural analysis showed that LTE damaged mitochondria in retinal ganglion cells and in the inner plexiform layer. Thus, LTE to low-intensity blue light harms the retinas of albino Wistar rats." @default.
- W4361010802 created "2023-03-30" @default.
- W4361010802 creator A5036456955 @default.
- W4361010802 creator A5055836761 @default.
- W4361010802 creator A5059723620 @default.
- W4361010802 creator A5075565008 @default.
- W4361010802 creator A5079723045 @default.
- W4361010802 date "2023-03-26" @default.
- W4361010802 modified "2023-09-26" @default.
- W4361010802 title "Low-Intensity Blue Light Exposure Reduces Melanopsin Expression in Intrinsically Photosensitive Retinal Ganglion Cells and Damages Mitochondria in Retinal Ganglion Cells in Wistar Rats" @default.
- W4361010802 cites W1496486528 @default.
- W4361010802 cites W1514977366 @default.
- W4361010802 cites W1578066525 @default.
- W4361010802 cites W1951724000 @default.
- W4361010802 cites W1968590695 @default.
- W4361010802 cites W1969540409 @default.
- W4361010802 cites W1971254250 @default.
- W4361010802 cites W1981673824 @default.
- W4361010802 cites W1984602692 @default.
- W4361010802 cites W1994807744 @default.
- W4361010802 cites W1996384089 @default.
- W4361010802 cites W2004381001 @default.
- W4361010802 cites W2005542815 @default.
- W4361010802 cites W2011695291 @default.
- W4361010802 cites W2014174952 @default.
- W4361010802 cites W2018398696 @default.
- W4361010802 cites W2022197238 @default.
- W4361010802 cites W2032235100 @default.
- W4361010802 cites W2038520118 @default.
- W4361010802 cites W2038769472 @default.
- W4361010802 cites W2042179612 @default.
- W4361010802 cites W2045912466 @default.
- W4361010802 cites W2046289352 @default.
- W4361010802 cites W2048270119 @default.
- W4361010802 cites W2059691962 @default.
- W4361010802 cites W2060128569 @default.
- W4361010802 cites W2066674350 @default.
- W4361010802 cites W2069342665 @default.
- W4361010802 cites W2071272327 @default.
- W4361010802 cites W2073575126 @default.
- W4361010802 cites W2075577721 @default.
- W4361010802 cites W2081957674 @default.
- W4361010802 cites W2092510003 @default.
- W4361010802 cites W2094302526 @default.
- W4361010802 cites W2095889022 @default.
- W4361010802 cites W2105050095 @default.
- W4361010802 cites W2123940005 @default.
- W4361010802 cites W2135393774 @default.
- W4361010802 cites W2396811347 @default.
- W4361010802 cites W2413463426 @default.
- W4361010802 cites W2538984373 @default.
- W4361010802 cites W2610319075 @default.
- W4361010802 cites W2615845725 @default.
- W4361010802 cites W2620282395 @default.
- W4361010802 cites W2748219340 @default.
- W4361010802 cites W2790881202 @default.
- W4361010802 cites W2910038554 @default.
- W4361010802 cites W2915682382 @default.
- W4361010802 cites W2947327091 @default.
- W4361010802 cites W3001985459 @default.
- W4361010802 cites W3016303389 @default.
- W4361010802 cites W3196852581 @default.
- W4361010802 cites W4205974073 @default.
- W4361010802 cites W4231964128 @default.
- W4361010802 cites W4232005894 @default.
- W4361010802 cites W4250940418 @default.
- W4361010802 cites W4292236404 @default.
- W4361010802 cites W4309714544 @default.
- W4361010802 cites W80931887 @default.
- W4361010802 cites W2735092478 @default.
- W4361010802 doi "https://doi.org/10.3390/cells12071014" @default.
- W4361010802 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37048087" @default.
- W4361010802 hasPublicationYear "2023" @default.
- W4361010802 type Work @default.
- W4361010802 citedByCount "0" @default.
- W4361010802 crossrefType "journal-article" @default.
- W4361010802 hasAuthorship W4361010802A5036456955 @default.
- W4361010802 hasAuthorship W4361010802A5055836761 @default.
- W4361010802 hasAuthorship W4361010802A5059723620 @default.
- W4361010802 hasAuthorship W4361010802A5075565008 @default.
- W4361010802 hasAuthorship W4361010802A5079723045 @default.
- W4361010802 hasBestOaLocation W43610108021 @default.
- W4361010802 hasConcept C105702510 @default.
- W4361010802 hasConcept C169760540 @default.
- W4361010802 hasConcept C185592680 @default.
- W4361010802 hasConcept C189780591 @default.
- W4361010802 hasConcept C203014093 @default.
- W4361010802 hasConcept C204232928 @default.
- W4361010802 hasConcept C2777093970 @default.
- W4361010802 hasConcept C2777506830 @default.
- W4361010802 hasConcept C2777585161 @default.
- W4361010802 hasConcept C2777624874 @default.
- W4361010802 hasConcept C2778231335 @default.
- W4361010802 hasConcept C2780188069 @default.
- W4361010802 hasConcept C2780495277 @default.
- W4361010802 hasConcept C2780827179 @default.
- W4361010802 hasConcept C2781099447 @default.
- W4361010802 hasConcept C2781334511 @default.