Matches in SemOpenAlex for { <https://semopenalex.org/work/W4361228853> ?p ?o ?g. }
- W4361228853 endingPage "103421" @default.
- W4361228853 startingPage "103421" @default.
- W4361228853 abstract "Late-onset sepsis is a frequent complication in neonatal intensive care units. This study aims to understand the effect of late-onset sepsis on mortality in hospitalised neonatal patients across different gestational ages. This is a single-centre, historical cohort study including neonates admitted to hospital during a 10-year period (2002 – 2011). Neonates were stratified by gestational age: extremely preterm (<28 weeks), very preterm (28 to 32 weeks), late preterm (33 to 36 weeks), full term (>37 weeks). Tertiary NICU in Ghent, Belgium. Logistic regression analysis was used to assess adjusted relationships between late-onset sepsis and mortality, reported as odds ratio (OR) and 95% confidence interval (CI). A total of 4928 neonates were included, of which 2071 were term (42.0%), 1425 were late preterm (28.9%), 1165 very preterm (23.6%) and 264 were extremely preterm neonates (5.4%). 40 neonates developed late-onset sepsis (8.2 episodes/1000 patient days). Overall, in-hospital mortality was 5.4%. Late-onset sepsis was an independent risk factor for mortality in the total cohort (OR = 2.41; 95% CI = 1.46–3.96). However, when gestational age groups were considered separately, late-onset sepsis was associated with mortality in very preterm neonates (OR = 2.45; 95% CI = 1.03–5.84) and in the late preterm neonates (OR = 3.92; 95% CI = 1.41–10.87), but not in other neonates. Comorbidities burdening neonatal hospital survival include acute lung disease, brain damage, periventricular leukomalacia, surgery, and broncho-pulmonary dysplasia. Late-onset sepsis is an independent risk factor for mortality in very preterm and late preterm neonates. Understanding how late-onset sepsis among other factors impact mortality enables a patient and family-centred approach to nursing care including the anticipation of realistic milestones. Late-onset sepsis is especially detrimental to preterm neonates and this could be taken into consideration by nurses when communicating with families in the perinatal period." @default.
- W4361228853 created "2023-03-31" @default.
- W4361228853 creator A5012821442 @default.
- W4361228853 creator A5051599989 @default.
- W4361228853 creator A5058667671 @default.
- W4361228853 creator A5068047257 @default.
- W4361228853 creator A5071709897 @default.
- W4361228853 date "2023-08-01" @default.
- W4361228853 modified "2023-10-01" @default.
- W4361228853 title "The effect of late-onset sepsis on mortality across different gestational ages in a neonatal intensive care unit: A historical study" @default.
- W4361228853 cites W1104973255 @default.
- W4361228853 cites W1857797615 @default.
- W4361228853 cites W1975968871 @default.
- W4361228853 cites W1981360765 @default.
- W4361228853 cites W1992389850 @default.
- W4361228853 cites W1999030169 @default.
- W4361228853 cites W2009941198 @default.
- W4361228853 cites W2017046795 @default.
- W4361228853 cites W2022647578 @default.
- W4361228853 cites W20272483 @default.
- W4361228853 cites W2035387676 @default.
- W4361228853 cites W2044599763 @default.
- W4361228853 cites W2050202211 @default.
- W4361228853 cites W2053301492 @default.
- W4361228853 cites W2064723143 @default.
- W4361228853 cites W2091076377 @default.
- W4361228853 cites W2094309995 @default.
- W4361228853 cites W2100070272 @default.
- W4361228853 cites W2107478273 @default.
- W4361228853 cites W2114685399 @default.
- W4361228853 cites W2139550427 @default.
- W4361228853 cites W2148044501 @default.
- W4361228853 cites W2151003604 @default.
- W4361228853 cites W2155248348 @default.
- W4361228853 cites W2160257370 @default.
- W4361228853 cites W2160948622 @default.
- W4361228853 cites W2223012991 @default.
- W4361228853 cites W2333905278 @default.
- W4361228853 cites W2342611028 @default.
- W4361228853 cites W2521978399 @default.
- W4361228853 cites W2735301415 @default.
- W4361228853 cites W2756367464 @default.
- W4361228853 cites W2771759037 @default.
- W4361228853 cites W2890437762 @default.
- W4361228853 cites W2907198977 @default.
- W4361228853 cites W2974810757 @default.
- W4361228853 cites W2988264143 @default.
- W4361228853 cites W2989691968 @default.
- W4361228853 cites W3127390171 @default.
- W4361228853 cites W3147489241 @default.
- W4361228853 cites W3162249954 @default.
- W4361228853 cites W3202964273 @default.
- W4361228853 cites W4214843537 @default.
- W4361228853 cites W4242194556 @default.
- W4361228853 cites W4255232901 @default.
- W4361228853 doi "https://doi.org/10.1016/j.iccn.2023.103421" @default.
- W4361228853 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37001447" @default.
- W4361228853 hasPublicationYear "2023" @default.
- W4361228853 type Work @default.
- W4361228853 citedByCount "1" @default.
- W4361228853 countsByYear W43612288532023 @default.
- W4361228853 crossrefType "journal-article" @default.
- W4361228853 hasAuthorship W4361228853A5012821442 @default.
- W4361228853 hasAuthorship W4361228853A5051599989 @default.
- W4361228853 hasAuthorship W4361228853A5058667671 @default.
- W4361228853 hasAuthorship W4361228853A5068047257 @default.
- W4361228853 hasAuthorship W4361228853A5071709897 @default.
- W4361228853 hasConcept C126322002 @default.
- W4361228853 hasConcept C141071460 @default.
- W4361228853 hasConcept C156957248 @default.
- W4361228853 hasConcept C177713679 @default.
- W4361228853 hasConcept C187212893 @default.
- W4361228853 hasConcept C201903717 @default.
- W4361228853 hasConcept C2776376669 @default.
- W4361228853 hasConcept C2777091541 @default.
- W4361228853 hasConcept C2778376644 @default.
- W4361228853 hasConcept C2778384902 @default.
- W4361228853 hasConcept C2778721537 @default.
- W4361228853 hasConcept C2779234561 @default.
- W4361228853 hasConcept C2780123866 @default.
- W4361228853 hasConcept C2987404301 @default.
- W4361228853 hasConcept C54355233 @default.
- W4361228853 hasConcept C71924100 @default.
- W4361228853 hasConcept C72563966 @default.
- W4361228853 hasConcept C86803240 @default.
- W4361228853 hasConceptScore W4361228853C126322002 @default.
- W4361228853 hasConceptScore W4361228853C141071460 @default.
- W4361228853 hasConceptScore W4361228853C156957248 @default.
- W4361228853 hasConceptScore W4361228853C177713679 @default.
- W4361228853 hasConceptScore W4361228853C187212893 @default.
- W4361228853 hasConceptScore W4361228853C201903717 @default.
- W4361228853 hasConceptScore W4361228853C2776376669 @default.
- W4361228853 hasConceptScore W4361228853C2777091541 @default.
- W4361228853 hasConceptScore W4361228853C2778376644 @default.
- W4361228853 hasConceptScore W4361228853C2778384902 @default.
- W4361228853 hasConceptScore W4361228853C2778721537 @default.
- W4361228853 hasConceptScore W4361228853C2779234561 @default.
- W4361228853 hasConceptScore W4361228853C2780123866 @default.