FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4361267172> ?p ?o ?g. }

• W4361267172 endingPage "e0283716" @default.
• W4361267172 startingPage "e0283716" @default.
• W4361267172 abstract "An increased blood pressure is a known comorbidity of both type 1 diabetes (T1DM) and obesity in children. Increasing evidence suggests a subtle interplay between epidermal growth factor (EGF) and renin along the juxtaglomerular system, regulating the impact of blood pressure on kidney health and the cardiovascular system. In this study, we investigated the relation between urinary EGF, serum renin and blood pressure in children with obesity or T1DM. 147 non-obese children with T1DM and 126 children with obesity, were included. Blood pressure was measured and mean arterial pressure (MAP) and the pulse pressure (PP) were calculated. Serum renin and urinary EGF levels were determined with a commercial ELISA kit. Partial Spearman rank correlation coefficients and multiple linear regression models were used to study the association between renin, the urinary EGF/urinary creatinine ratio and blood pressure parameters. The urinary EGF/urinary creatinine ratio is correlated with the SBP and the MAP in boys with obesity as well as in boys with T1DM. Multiple regression analysis showed that sex and pulse pressure in male subjects were found to be independently associated with renin. Sex, the presence of diabetes, age, the glomerular filtration rate and both pulse pressure and mean arterial pressure in male subjects were independently associated with urinary EGF/urinary creatinine. In conclusion, in boys with either obesity or diabetes, pulse pressure and mean arterial pressure are negatively associated with the functional integrity of the nephron, which is reflected by a decreased expression of urinary EGF." @default.
• W4361267172 created "2023-03-31" @default.
• W4361267172 creator A5013618589 @default.
• W4361267172 creator A5020606887 @default.
• W4361267172 creator A5025029198 @default.
• W4361267172 creator A5026664820 @default.
• W4361267172 creator A5028838249 @default.
• W4361267172 creator A5043677221 @default.
• W4361267172 creator A5056938065 @default.
• W4361267172 creator A5067252523 @default.
• W4361267172 creator A5081457322 @default.
• W4361267172 creator A5085344739 @default.
• W4361267172 creator A5086011281 @default.
• W4361267172 date "2023-03-30" @default.
• W4361267172 modified "2023-10-01" @default.
• W4361267172 title "Urinary epidermal growth factor reflects vascular health in boys with either obesity or type 1 diabetes. A role for renin, or beyond?" @default.
• W4361267172 cites W1899551827 @default.
• W4361267172 cites W1964737507 @default.
• W4361267172 cites W1966338613 @default.
• W4361267172 cites W1972905705 @default.
• W4361267172 cites W1976369475 @default.
• W4361267172 cites W1979955764 @default.
• W4361267172 cites W1987243476 @default.
• W4361267172 cites W2001760768 @default.
• W4361267172 cites W2011869586 @default.
• W4361267172 cites W2023793692 @default.
• W4361267172 cites W2028439883 @default.
• W4361267172 cites W2042480476 @default.
• W4361267172 cites W2046221582 @default.
• W4361267172 cites W2058724069 @default.
• W4361267172 cites W2071993867 @default.
• W4361267172 cites W2076820134 @default.
• W4361267172 cites W2080844882 @default.
• W4361267172 cites W2085077767 @default.
• W4361267172 cites W2103203052 @default.
• W4361267172 cites W2104129218 @default.
• W4361267172 cites W2115609973 @default.
• W4361267172 cites W2117666385 @default.
• W4361267172 cites W2122855609 @default.
• W4361267172 cites W2156842176 @default.
• W4361267172 cites W2258981636 @default.
• W4361267172 cites W2552825608 @default.
• W4361267172 cites W2747721206 @default.
• W4361267172 cites W2807874855 @default.
• W4361267172 cites W2807893746 @default.
• W4361267172 cites W2810098275 @default.
• W4361267172 cites W2888827665 @default.
• W4361267172 cites W2898265919 @default.
• W4361267172 cites W2911265062 @default.
• W4361267172 cites W2967996496 @default.
• W4361267172 cites W3017621350 @default.
• W4361267172 cites W3080638280 @default.
• W4361267172 cites W3118251891 @default.
• W4361267172 cites W3119651053 @default.
• W4361267172 cites W3137382507 @default.
• W4361267172 cites W3179070319 @default.
• W4361267172 cites W3182904419 @default.
• W4361267172 cites W3194901459 @default.
• W4361267172 cites W3215771168 @default.
• W4361267172 cites W4229006307 @default.
• W4361267172 cites W4240272416 @default.
• W4361267172 doi "https://doi.org/10.1371/journal.pone.0283716" @default.
• W4361267172 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36996194" @default.
• W4361267172 hasPublicationYear "2023" @default.
• W4361267172 type Work @default.
• W4361267172 citedByCount "0" @default.
• W4361267172 crossrefType "journal-article" @default.
• W4361267172 hasAuthorship W4361267172A5013618589 @default.
• W4361267172 hasAuthorship W4361267172A5020606887 @default.
• W4361267172 hasAuthorship W4361267172A5025029198 @default.
• W4361267172 hasAuthorship W4361267172A5026664820 @default.
• W4361267172 hasAuthorship W4361267172A5028838249 @default.
• W4361267172 hasAuthorship W4361267172A5043677221 @default.
• W4361267172 hasAuthorship W4361267172A5056938065 @default.
• W4361267172 hasAuthorship W4361267172A5067252523 @default.
• W4361267172 hasAuthorship W4361267172A5081457322 @default.
• W4361267172 hasAuthorship W4361267172A5085344739 @default.
• W4361267172 hasAuthorship W4361267172A5086011281 @default.
• W4361267172 hasBestOaLocation W43612671721 @default.
• W4361267172 hasConcept C126322002 @default.
• W4361267172 hasConcept C134018914 @default.
• W4361267172 hasConcept C138976137 @default.
• W4361267172 hasConcept C159641895 @default.
• W4361267172 hasConcept C17140001 @default.
• W4361267172 hasConcept C198710026 @default.
• W4361267172 hasConcept C2777180221 @default.
• W4361267172 hasConcept C2780306776 @default.
• W4361267172 hasConcept C511355011 @default.
• W4361267172 hasConcept C555293320 @default.
• W4361267172 hasConcept C71924100 @default.
• W4361267172 hasConcept C77411442 @default.
• W4361267172 hasConcept C84393581 @default.
• W4361267172 hasConceptScore W4361267172C126322002 @default.
• W4361267172 hasConceptScore W4361267172C134018914 @default.
• W4361267172 hasConceptScore W4361267172C138976137 @default.
• W4361267172 hasConceptScore W4361267172C159641895 @default.
• W4361267172 hasConceptScore W4361267172C17140001 @default.
• W4361267172 hasConceptScore W4361267172C198710026 @default.

• next