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- W4361280758 abstract "The addition of cryobiopsy to conventional biopsy methods improves the diagnostic yield of peripheral pulmonary lesions. Moreover, cryobiopsy with a guide sheath (GS) provides additional diagnostic benefits. Semi-real-time biopsy can be repeatedly performed using conventional biopsy devices and a GS, and subsequent cryobiopsy can be easily performed at the same location. Recently, a disposable 1.1 mm-diameter ultrathin cryoprobe has been developed and can be used with a 1.95 mm GS in a 2.0 mm working channel. In this study, we evaluated the diagnostic performance of transbronchial lung cryobiopsy (TBLC) with the 1.1 mm cryoprobe and a GS in patients with peripheral pulmonary lesions.We retrospectively reviewed the medical records of patients who underwent endobronchial ultrasound transbronchial lung biopsy with a guide sheath and TBLC from July 23, 2021 to April 30, 2022 at Chungnam National University Hospital.Of a consecutive series of 229 patients, 199 were included. The diagnostic yields of forceps biopsy and cryobiopsy were 65.3% (130/199) and 84.4% (168/199), respectively, and the total diagnostic yield was 91.5% (182/199) (P<0.001 vs. forceps biopsy). Multivariate analysis showed that solid lesion morphology [adjusted odds ratio (OR) 3.659, P=0.002] was associated with a significantly greater diagnostic yield of cryobiopsy, whereas a lesion diameter >20 mm (P=0.026; adjusted OR 3.816) and 'within' orientation (P=0.004; adjusted OR 6.174) were associated with a significantly greater overall diagnostic yield.TBLC using an ultrathin cryoprobe and GS markedly improves the diagnostic yield." @default.
- W4361280758 created "2023-03-31" @default.
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- W4361280758 date "2023-03-30" @default.
- W4361280758 modified "2023-09-25" @default.
- W4361280758 title "Diagnostic Value of Transbronchial Lung Cryobiopsy using an Ultrathin Cryoprobe and Guide Sheath for Peripheral Pulmonary Lesions" @default.
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- W4361280758 doi "https://doi.org/10.1097/lbr.0000000000000917" @default.
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