Matches in SemOpenAlex for { <https://semopenalex.org/work/W4361285634> ?p ?o ?g. }
Showing items 1 to 71 of
71
with 100 items per page.
- W4361285634 abstract "Background Patients presenting with head and neck squamous cell carcinoma of unknown primary (HNSCCUP) remain challenging clinical scenarios as large variation exists in practices used to locate the primary. Objective To perform a systematic review of the literature and offer recommendations for oropharyngeal biopsies in HNSCCUP. Method Pubmed, Medline and Embase were searched to identify studies from inception to October 2021. The Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) guidelines were followed. Results 483 articles were included and screened, 40 studies met the inclusion criteria, including over 3400 patients from the original articles and 1575 patients from 3 meta-analyses. The primary site identification rate following random biopsies or deep tissue biopsies is less than 5% in most studies. The mean detection rate following ipsilateral tonsillectomy is 34%; two pooled analyses indicate that the mean detection rate following tongue base mucosectomy is 64%, with this figure rising when the tonsils are negative. Conclusions High level evidence is lacking, with heterogeneity in the reported studies. Published meta analyses are based on retrospective data. There is little evidence supporting the practice of random/non-directed oropharyngeal biopsies. Available evidence supports palatine tonsillectomy and tongue base mucosectomy compared to deep tissue biopsies." @default.
- W4361285634 created "2023-03-31" @default.
- W4361285634 creator A5001218766 @default.
- W4361285634 creator A5008784468 @default.
- W4361285634 creator A5027676682 @default.
- W4361285634 creator A5090028264 @default.
- W4361285634 date "2023-03-29" @default.
- W4361285634 modified "2023-10-17" @default.
- W4361285634 title "Indications for Oropharyngeal Biopsy in Head and Neck Squamous Cell Carcinoma of Unknown Primary - A Systematic Review (HNSCCUP)" @default.
- W4361285634 doi "https://doi.org/10.22541/au.168006790.09454233/v1" @default.
- W4361285634 hasPublicationYear "2023" @default.
- W4361285634 type Work @default.
- W4361285634 citedByCount "0" @default.
- W4361285634 crossrefType "posted-content" @default.
- W4361285634 hasAuthorship W4361285634A5001218766 @default.
- W4361285634 hasAuthorship W4361285634A5008784468 @default.
- W4361285634 hasAuthorship W4361285634A5027676682 @default.
- W4361285634 hasAuthorship W4361285634A5090028264 @default.
- W4361285634 hasBestOaLocation W43612856341 @default.
- W4361285634 hasConcept C121608353 @default.
- W4361285634 hasConcept C126322002 @default.
- W4361285634 hasConcept C141071460 @default.
- W4361285634 hasConcept C142724271 @default.
- W4361285634 hasConcept C17744445 @default.
- W4361285634 hasConcept C189708586 @default.
- W4361285634 hasConcept C199539241 @default.
- W4361285634 hasConcept C2775934546 @default.
- W4361285634 hasConcept C2776530083 @default.
- W4361285634 hasConcept C2776833033 @default.
- W4361285634 hasConcept C2777546739 @default.
- W4361285634 hasConcept C2779073326 @default.
- W4361285634 hasConcept C2779473830 @default.
- W4361285634 hasConcept C2779744641 @default.
- W4361285634 hasConcept C3018411727 @default.
- W4361285634 hasConcept C3019992690 @default.
- W4361285634 hasConcept C71924100 @default.
- W4361285634 hasConcept C95190672 @default.
- W4361285634 hasConceptScore W4361285634C121608353 @default.
- W4361285634 hasConceptScore W4361285634C126322002 @default.
- W4361285634 hasConceptScore W4361285634C141071460 @default.
- W4361285634 hasConceptScore W4361285634C142724271 @default.
- W4361285634 hasConceptScore W4361285634C17744445 @default.
- W4361285634 hasConceptScore W4361285634C189708586 @default.
- W4361285634 hasConceptScore W4361285634C199539241 @default.
- W4361285634 hasConceptScore W4361285634C2775934546 @default.
- W4361285634 hasConceptScore W4361285634C2776530083 @default.
- W4361285634 hasConceptScore W4361285634C2776833033 @default.
- W4361285634 hasConceptScore W4361285634C2777546739 @default.
- W4361285634 hasConceptScore W4361285634C2779073326 @default.
- W4361285634 hasConceptScore W4361285634C2779473830 @default.
- W4361285634 hasConceptScore W4361285634C2779744641 @default.
- W4361285634 hasConceptScore W4361285634C3018411727 @default.
- W4361285634 hasConceptScore W4361285634C3019992690 @default.
- W4361285634 hasConceptScore W4361285634C71924100 @default.
- W4361285634 hasConceptScore W4361285634C95190672 @default.
- W4361285634 hasLocation W43612856341 @default.
- W4361285634 hasOpenAccess W4361285634 @default.
- W4361285634 hasPrimaryLocation W43612856341 @default.
- W4361285634 hasRelatedWork W1686768521 @default.
- W4361285634 hasRelatedWork W1968768545 @default.
- W4361285634 hasRelatedWork W2032316264 @default.
- W4361285634 hasRelatedWork W2068029534 @default.
- W4361285634 hasRelatedWork W2092701849 @default.
- W4361285634 hasRelatedWork W2131919804 @default.
- W4361285634 hasRelatedWork W2328984931 @default.
- W4361285634 hasRelatedWork W2905533770 @default.
- W4361285634 hasRelatedWork W2995249508 @default.
- W4361285634 hasRelatedWork W3099315141 @default.
- W4361285634 isParatext "false" @default.
- W4361285634 isRetracted "false" @default.
- W4361285634 workType "article" @default.