Matches in SemOpenAlex for { <https://semopenalex.org/work/W4361286918> ?p ?o ?g. }
Showing items 1 to 67 of
67
with 100 items per page.
- W4361286918 endingPage "280" @default.
- W4361286918 startingPage "273" @default.
- W4361286918 abstract "The Current European Society of Cardiology guidelines indicate specific target low-density lipoprotein cholesterol (LDL-C) levels for different cardiovascular risk categories in terms of prevention. However, the target for high-density lipoprotein cholesterol (HDL-C) and triglycerides has not been established.The study aims to investigate the associations betweenHDL-C,triglycerides, andcoronary plaque characteristics.This was a prospective single-center study with enrolled consecutive patients with newly diagnosed significant (≥1stenosis ≥50%) CAD on computed tomography coronary angiography (CTCA). Patients had lipids andCTCA analysis, including high-risk plaque (HRP) features: low-attenuation plaque (LAP), napkin-ring sign (NRS), positive remodeling (PR), and spotty calcium (SC), type of the plaque (calcified, noncalcified, mixed), and their composition (calcified, fibrous, fibro-fatty, necrotic core).The study included 300 patients (191 men, 66 [8] years). Sixty-six percent of them had lipid-lowering therapy. HRPwas found in 208 patients. There was no association between LDL-C, plaque composition, and HRP presence. There was a negative correlation between HDL-C, fibro-fatty and necrotic core plaque components (P = 0.0002, P = 0.0009). There was a positive correlation between triglycerides and necrotic core (P = 0.038). There were differences in HDL-C and triglycerides in patients with and without NRS (47 vs. 53 mg/dl, P = 0.0002 and 128 vs. 109 mg/dl, P = 0.02). In logistic regression, HDL-C (odds ratio [OR], 0.95;95% confidence interval [CI], 0.93-0.98; P <0.001), triglycerides (OR, 1.00; 95% CI, 1.00-1.01; P = 0.02), and male sex (OR, 3.04; 95% CI, 1.41-6.52; P = 0.004) were NRS predictors. In multivariable regression, only HDL-C (OR, 0.96; 95% CI, 0.93-0.99; P = 0.02) was an independent predictor of NRS.Lower HDL-C and higher triglycerides were associated with NRS presence and more necrotic core plaque components in coronary plaques in patients with newly diagnosed CAD." @default.
- W4361286918 created "2023-03-31" @default.
- W4361286918 creator A5034839973 @default.
- W4361286918 creator A5035158874 @default.
- W4361286918 creator A5037935406 @default.
- W4361286918 creator A5068658344 @default.
- W4361286918 creator A5078024797 @default.
- W4361286918 creator A5081615502 @default.
- W4361286918 date "2023-03-27" @default.
- W4361286918 modified "2023-10-16" @default.
- W4361286918 title "High-density lipoprotein cholesterol, triglycerides, and characteristics of coronary atherosclerosis in patients with significant coronary artery disease newly diagnosed by computed tomography coronary angiography" @default.
- W4361286918 doi "https://doi.org/10.33963/kp.a2022.0279" @default.
- W4361286918 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36475513" @default.
- W4361286918 hasPublicationYear "2023" @default.
- W4361286918 type Work @default.
- W4361286918 citedByCount "0" @default.
- W4361286918 crossrefType "journal-article" @default.
- W4361286918 hasAuthorship W4361286918A5034839973 @default.
- W4361286918 hasAuthorship W4361286918A5035158874 @default.
- W4361286918 hasAuthorship W4361286918A5037935406 @default.
- W4361286918 hasAuthorship W4361286918A5068658344 @default.
- W4361286918 hasAuthorship W4361286918A5078024797 @default.
- W4361286918 hasAuthorship W4361286918A5081615502 @default.
- W4361286918 hasBestOaLocation W43612869181 @default.
- W4361286918 hasConcept C126322002 @default.
- W4361286918 hasConcept C156957248 @default.
- W4361286918 hasConcept C164705383 @default.
- W4361286918 hasConcept C2778163477 @default.
- W4361286918 hasConcept C2778213512 @default.
- W4361286918 hasConcept C2779179121 @default.
- W4361286918 hasConcept C2780541478 @default.
- W4361286918 hasConcept C2991716557 @default.
- W4361286918 hasConcept C44249647 @default.
- W4361286918 hasConcept C71924100 @default.
- W4361286918 hasConcept C90924648 @default.
- W4361286918 hasConceptScore W4361286918C126322002 @default.
- W4361286918 hasConceptScore W4361286918C156957248 @default.
- W4361286918 hasConceptScore W4361286918C164705383 @default.
- W4361286918 hasConceptScore W4361286918C2778163477 @default.
- W4361286918 hasConceptScore W4361286918C2778213512 @default.
- W4361286918 hasConceptScore W4361286918C2779179121 @default.
- W4361286918 hasConceptScore W4361286918C2780541478 @default.
- W4361286918 hasConceptScore W4361286918C2991716557 @default.
- W4361286918 hasConceptScore W4361286918C44249647 @default.
- W4361286918 hasConceptScore W4361286918C71924100 @default.
- W4361286918 hasConceptScore W4361286918C90924648 @default.
- W4361286918 hasIssue "3" @default.
- W4361286918 hasLocation W43612869181 @default.
- W4361286918 hasLocation W43612869182 @default.
- W4361286918 hasOpenAccess W4361286918 @default.
- W4361286918 hasPrimaryLocation W43612869181 @default.
- W4361286918 hasRelatedWork W1990277803 @default.
- W4361286918 hasRelatedWork W2072909849 @default.
- W4361286918 hasRelatedWork W2084657674 @default.
- W4361286918 hasRelatedWork W2088836697 @default.
- W4361286918 hasRelatedWork W2101393751 @default.
- W4361286918 hasRelatedWork W2149494111 @default.
- W4361286918 hasRelatedWork W2392216433 @default.
- W4361286918 hasRelatedWork W2548606733 @default.
- W4361286918 hasRelatedWork W2770217523 @default.
- W4361286918 hasRelatedWork W2888906357 @default.
- W4361286918 hasVolume "81" @default.
- W4361286918 isParatext "false" @default.
- W4361286918 isRetracted "false" @default.
- W4361286918 workType "article" @default.