FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4361296000> ?p ?o ?g. }

• W4361296000 endingPage "6365" @default.
• W4361296000 startingPage "6365" @default.
• W4361296000 abstract "Traumatic brain injury is a leading cause of neuroinflammation and anxiety disorders in young adults. Immune-targeted therapies have garnered attention for the amelioration of TBI-induced anxiety. A previous study has indicated that voluntary exercise intervention following TBI could reduce neuroinflammation. It is essential to determine the effects of voluntary exercise after TBI on anxiety via inhibiting neuroinflammatory response. Mice were randomly divided into four groups (sham, TBI, sham + voluntary wheel running (VWR), and TBI + VWR). One-week VWR was carried out on the 2nd day after trauma. The neurofunction of TBI mice was assessed. Following VWR, anxiety behavior was evaluated, and neuroinflammatory responses in the perilesional cortex were investigated. Results showed that after one week of VWR, neurofunctional recovery was enhanced, while the anxiety behavior of TBI mice was significantly alleviated. The level of pro-inflammatory factors decreased, and the level of anti-inflammatory factors elevated. Activation of nucleotide oligomerization domain-like thermal receptor protein domain associated protein 3 (NLRP3) inflammasome was inhibited significantly. All these alterations were consistent with reduced microglial activation at the perilesional site and positively correlated with the amelioration of anxiety behavior. This suggested that timely rehabilitative exercise could be a useful therapeutic strategy for anxiety resulting from TBI by targeting neuroinflammation." @default.
• W4361296000 created "2023-03-31" @default.
• W4361296000 creator A5003604316 @default.
• W4361296000 creator A5010260063 @default.
• W4361296000 creator A5013303786 @default.
• W4361296000 creator A5037040539 @default.
• W4361296000 creator A5040571329 @default.
• W4361296000 creator A5047616263 @default.
• W4361296000 creator A5055223725 @default.
• W4361296000 creator A5055514493 @default.
• W4361296000 creator A5061856481 @default.
• W4361296000 creator A5067408527 @default.
• W4361296000 creator A5073217691 @default.
• W4361296000 date "2023-03-28" @default.
• W4361296000 modified "2023-09-25" @default.
• W4361296000 title "Voluntary Exercise to Reduce Anxiety Behaviour in Traumatic Brain Injury Shown to Alleviate Inflammatory Brain Response in Mice" @default.
• W4361296000 cites W1692987496 @default.
• W4361296000 cites W1944132044 @default.
• W4361296000 cites W1975076162 @default.
• W4361296000 cites W2004631917 @default.
• W4361296000 cites W2019260483 @default.
• W4361296000 cites W2019553927 @default.
• W4361296000 cites W2026209203 @default.
• W4361296000 cites W2043485493 @default.
• W4361296000 cites W2065828939 @default.
• W4361296000 cites W2098752569 @default.
• W4361296000 cites W2130198578 @default.
• W4361296000 cites W2158102712 @default.
• W4361296000 cites W2159744238 @default.
• W4361296000 cites W2171704252 @default.
• W4361296000 cites W2176073293 @default.
• W4361296000 cites W2332094297 @default.
• W4361296000 cites W2343079527 @default.
• W4361296000 cites W2345917271 @default.
• W4361296000 cites W2423496620 @default.
• W4361296000 cites W2475265111 @default.
• W4361296000 cites W2499852969 @default.
• W4361296000 cites W2521031702 @default.
• W4361296000 cites W2526567150 @default.
• W4361296000 cites W2529044272 @default.
• W4361296000 cites W2534253241 @default.
• W4361296000 cites W2554208398 @default.
• W4361296000 cites W2560416815 @default.
• W4361296000 cites W2586825713 @default.
• W4361296000 cites W2600402820 @default.
• W4361296000 cites W2735978036 @default.
• W4361296000 cites W2754554955 @default.
• W4361296000 cites W2891307472 @default.
• W4361296000 cites W2894437797 @default.
• W4361296000 cites W2903325146 @default.
• W4361296000 cites W2912370667 @default.
• W4361296000 cites W2913493833 @default.
• W4361296000 cites W2914892110 @default.
• W4361296000 cites W2945862226 @default.
• W4361296000 cites W2976876257 @default.
• W4361296000 cites W3000542087 @default.
• W4361296000 cites W3008114116 @default.
• W4361296000 cites W3014364481 @default.
• W4361296000 cites W3029611494 @default.
• W4361296000 cites W3080545619 @default.
• W4361296000 cites W3091903672 @default.
• W4361296000 cites W3109048507 @default.
• W4361296000 cites W3135431224 @default.
• W4361296000 cites W3136680431 @default.
• W4361296000 cites W3145534257 @default.
• W4361296000 cites W3162229909 @default.
• W4361296000 cites W3167724866 @default.
• W4361296000 cites W3181596361 @default.
• W4361296000 cites W3209643077 @default.
• W4361296000 cites W3215314529 @default.
• W4361296000 cites W4220900846 @default.
• W4361296000 cites W4284887599 @default.
• W4361296000 doi "https://doi.org/10.3390/ijms24076365" @default.
• W4361296000 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37047351" @default.
• W4361296000 hasPublicationYear "2023" @default.
• W4361296000 type Work @default.
• W4361296000 citedByCount "0" @default.
• W4361296000 crossrefType "journal-article" @default.
• W4361296000 hasAuthorship W4361296000A5003604316 @default.
• W4361296000 hasAuthorship W4361296000A5010260063 @default.
• W4361296000 hasAuthorship W4361296000A5013303786 @default.
• W4361296000 hasAuthorship W4361296000A5037040539 @default.
• W4361296000 hasAuthorship W4361296000A5040571329 @default.
• W4361296000 hasAuthorship W4361296000A5047616263 @default.
• W4361296000 hasAuthorship W4361296000A5055223725 @default.
• W4361296000 hasAuthorship W4361296000A5055514493 @default.
• W4361296000 hasAuthorship W4361296000A5061856481 @default.
• W4361296000 hasAuthorship W4361296000A5067408527 @default.
• W4361296000 hasAuthorship W4361296000A5073217691 @default.
• W4361296000 hasBestOaLocation W43612960001 @default.
• W4361296000 hasConcept C118552586 @default.
• W4361296000 hasConcept C126322002 @default.
• W4361296000 hasConcept C15744967 @default.
• W4361296000 hasConcept C2776914184 @default.
• W4361296000 hasConcept C2777209026 @default.
• W4361296000 hasConcept C2779830541 @default.
• W4361296000 hasConcept C2781017439 @default.
• W4361296000 hasConcept C558461103 @default.

• next