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- W4361305965 endingPage "1237" @default.
- W4361305965 startingPage "1224" @default.
- W4361305965 abstract "Abstract We report a convenient two‐step approach to α‐amino ketones involving cross‐coupling and oxidative cleavage sequence. The cross‐coupling reaction creates a divergent functionalization of the molecular platform, e. g., N ‐(2‐bromoallyl)amine, whereas the oxidative cleavage establishes the carbonyl functionality. This strategy allows for an introduction of aryl/heteroaryl and alkyl groups, either through the Suzuki reaction with arylboronic acids or via dual photoredox/Ni‐catalysis to install alkyl groups. The oxidative cleavage to provide target α‐amino ketones can be realized either by treating with ozone or by employing milder photochemical protocols involving oxygen or photoexcited nitroarenes as oxidants. We successfully demonstrate the scalability of this protocol, which, together with its simplicity, generality, and its ability to provide access to amino ketones that are inaccessible through other strategies, highlights the suitability of this approach for a wide range of applications across the different chemical sciences. magnified image" @default.
- W4361305965 created "2023-03-31" @default.
- W4361305965 creator A5035221261 @default.
- W4361305965 creator A5018671619 @default.
- W4361305965 date "2023-04-13" @default.
- W4361305965 modified "2023-10-12" @default.
- W4361305965 title "Synthesis of Chiral α‐Amino Ketones via Transition Metal Catalyzed or Photoredox Cross‐Coupling and Olefin Photo‐Cleavage Reaction Sequence" @default.
- W4361305965 cites W1133479866 @default.
- W4361305965 cites W1961364466 @default.
- W4361305965 cites W1965317992 @default.
- W4361305965 cites W1968256979 @default.
- W4361305965 cites W1976998398 @default.
- W4361305965 cites W1978837202 @default.
- W4361305965 cites W1981990513 @default.
- W4361305965 cites W1989684129 @default.
- W4361305965 cites W2000335876 @default.
- W4361305965 cites W2001382096 @default.
- W4361305965 cites W2005764781 @default.
- W4361305965 cites W2009637509 @default.
- W4361305965 cites W2021469914 @default.
- W4361305965 cites W2021830949 @default.
- W4361305965 cites W2039933321 @default.
- W4361305965 cites W2042893358 @default.
- W4361305965 cites W2043856448 @default.
- W4361305965 cites W2049018532 @default.
- W4361305965 cites W2055061810 @default.
- W4361305965 cites W2060853924 @default.
- W4361305965 cites W2061430807 @default.
- W4361305965 cites W2061975161 @default.
- W4361305965 cites W2063661753 @default.
- W4361305965 cites W2068807655 @default.
- W4361305965 cites W2071404549 @default.
- W4361305965 cites W2072591300 @default.
- W4361305965 cites W2078634145 @default.
- W4361305965 cites W2084584682 @default.
- W4361305965 cites W2119430554 @default.
- W4361305965 cites W2127807351 @default.
- W4361305965 cites W2128324239 @default.
- W4361305965 cites W2137765175 @default.
- W4361305965 cites W2143036996 @default.
- W4361305965 cites W2146976622 @default.
- W4361305965 cites W2149501066 @default.
- W4361305965 cites W2149718536 @default.
- W4361305965 cites W2155224405 @default.
- W4361305965 cites W2160294427 @default.
- W4361305965 cites W2167085007 @default.
- W4361305965 cites W2170075322 @default.
- W4361305965 cites W2171866871 @default.
- W4361305965 cites W2224686011 @default.
- W4361305965 cites W2259291911 @default.
- W4361305965 cites W2273976432 @default.
- W4361305965 cites W2285469255 @default.
- W4361305965 cites W2316028640 @default.
- W4361305965 cites W2316577302 @default.
- W4361305965 cites W2318185398 @default.
- W4361305965 cites W2322685659 @default.
- W4361305965 cites W2322793294 @default.
- W4361305965 cites W2327985527 @default.
- W4361305965 cites W2335278712 @default.
- W4361305965 cites W2416710182 @default.
- W4361305965 cites W2441268982 @default.
- W4361305965 cites W2481437303 @default.
- W4361305965 cites W2484402238 @default.
- W4361305965 cites W2515068481 @default.
- W4361305965 cites W2528441550 @default.
- W4361305965 cites W2541670163 @default.
- W4361305965 cites W2584094937 @default.
- W4361305965 cites W2602269927 @default.
- W4361305965 cites W2608326801 @default.
- W4361305965 cites W2616001330 @default.
- W4361305965 cites W2732615433 @default.
- W4361305965 cites W2792564663 @default.
- W4361305965 cites W2895656588 @default.
- W4361305965 cites W2896001189 @default.
- W4361305965 cites W2897488733 @default.
- W4361305965 cites W2902748937 @default.
- W4361305965 cites W2915735630 @default.
- W4361305965 cites W2916983017 @default.
- W4361305965 cites W2922083180 @default.
- W4361305965 cites W2949232719 @default.
- W4361305965 cites W2951561665 @default.
- W4361305965 cites W2952074028 @default.
- W4361305965 cites W2970651984 @default.
- W4361305965 cites W2979701433 @default.
- W4361305965 cites W2982464351 @default.
- W4361305965 cites W2996323222 @default.
- W4361305965 cites W3004829780 @default.
- W4361305965 cites W3009123515 @default.
- W4361305965 cites W3011496751 @default.
- W4361305965 cites W3014816421 @default.
- W4361305965 cites W3028169059 @default.
- W4361305965 cites W3033134935 @default.
- W4361305965 cites W3038425813 @default.
- W4361305965 cites W3043318896 @default.
- W4361305965 cites W3044961123 @default.
- W4361305965 cites W3048341095 @default.
- W4361305965 cites W3054850573 @default.
- W4361305965 cites W3064309839 @default.