FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4361821255> ?p ?o ?g. }

• W4361821255 abstract "<div>Abstract<p><b>Background:</b> Adipocytokines, adipocyte-secreted hormones, play a critical role in breast cancer development. The expression of visfatin, a newly discovered adipocytokine, in breast cancer tissues was determined and correlated with patient clinicopathologic variables.</p><p><b>Methods:</b> Visfatin expression in breast cancer tissues was analyzed by immunohistochemistry. Visfatin expression was correlated with clinicopathologic variables as well as recurrence rates, using the χ² test. The prognostic value of visfatin for disease-free and overall survival was evaluated by Kaplan–Meier estimates, and the significance of differences between curves was evaluated by the log-rank test.</p><p><b>Results:</b> High visfatin expression in breast cancer tissues was significantly correlated with tumor size, estrogen receptor (ER) negativity, and progesterone receptor (PR) negativity. Hormone therapy, but not radiotherapy or chemotherapy, decreased the recurrence rate in patients with high visfatin expression. Whereas high visfatin expression alone was associated with poor disease-free and overall survival, worse disease-free and overall survival was observed when high visfatin expression was combined with ER- and PR-negative status. Cox regression analysis also revealed that visfatin is an independent predictor of disease-free and overall survival.</p><p><b>Conclusion:</b> High visfatin expression in breast cancer tissue is associated with more malignant cancer behavior as well as poor patient survival.</p><p><b>Impact:</b> Visfatin is an independent prognosis predictor for breast cancer. <i>Cancer Epidemiol Biomarkers Prev; 20(9); 1892–901. ©2011 AACR</i>.</p></div>" @default.
• W4361821255 created "2023-04-05" @default.
• W4361821255 creator A5006129657 @default.
• W4361821255 creator A5010892850 @default.
• W4361821255 creator A5058835244 @default.
• W4361821255 creator A5074664727 @default.
• W4361821255 creator A5078575765 @default.
• W4361821255 creator A5091443977 @default.
• W4361821255 date "2023-03-31" @default.
• W4361821255 modified "2023-10-16" @default.
• W4361821255 title "Data from High Visfatin Expression in Breast Cancer Tissue Is Associated with Poor Survival" @default.
• W4361821255 doi "https://doi.org/10.1158/1055-9965.c.6514897" @default.
• W4361821255 hasPublicationYear "2023" @default.
• W4361821255 type Work @default.
• W4361821255 citedByCount "0" @default.
• W4361821255 crossrefType "posted-content" @default.
• W4361821255 hasAuthorship W4361821255A5006129657 @default.
• W4361821255 hasAuthorship W4361821255A5010892850 @default.
• W4361821255 hasAuthorship W4361821255A5058835244 @default.
• W4361821255 hasAuthorship W4361821255A5074664727 @default.
• W4361821255 hasAuthorship W4361821255A5078575765 @default.
• W4361821255 hasAuthorship W4361821255A5091443977 @default.
• W4361821255 hasConcept C121608353 @default.
• W4361821255 hasConcept C126322002 @default.
• W4361821255 hasConcept C134018914 @default.
• W4361821255 hasConcept C143998085 @default.
• W4361821255 hasConcept C204232928 @default.
• W4361821255 hasConcept C530470458 @default.
• W4361821255 hasConcept C71924100 @default.
• W4361821255 hasConcept C84606932 @default.
• W4361821255 hasConceptScore W4361821255C121608353 @default.
• W4361821255 hasConceptScore W4361821255C126322002 @default.
• W4361821255 hasConceptScore W4361821255C134018914 @default.
• W4361821255 hasConceptScore W4361821255C143998085 @default.
• W4361821255 hasConceptScore W4361821255C204232928 @default.
• W4361821255 hasConceptScore W4361821255C530470458 @default.
• W4361821255 hasConceptScore W4361821255C71924100 @default.
• W4361821255 hasConceptScore W4361821255C84606932 @default.
• W4361821255 hasLocation W43618212551 @default.
• W4361821255 hasOpenAccess W4361821255 @default.
• W4361821255 hasPrimaryLocation W43618212551 @default.
• W4361821255 hasRelatedWork W1965298510 @default.
• W4361821255 hasRelatedWork W1970572904 @default.
• W4361821255 hasRelatedWork W1970614368 @default.
• W4361821255 hasRelatedWork W2046600857 @default.
• W4361821255 hasRelatedWork W2068408721 @default.
• W4361821255 hasRelatedWork W2093476509 @default.
• W4361821255 hasRelatedWork W2101821182 @default.
• W4361821255 hasRelatedWork W2150216118 @default.
• W4361821255 hasRelatedWork W2352033025 @default.
• W4361821255 hasRelatedWork W4232275671 @default.
• W4361821255 isParatext "false" @default.
• W4361821255 isRetracted "false" @default.
• W4361821255 workType "article" @default.