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• W4361923614 abstract "<p>Supplementary Figure 1. Overview of XPO1's role in nuclear:cytoplasmic transport. Supplementary Figure 2. KPT-185 is much less toxic to patient-derived benign cells than patient-derived serous high grade OvCa cells. Supplementary Figure 3. FACS cell cycle analysis of indicated cell lines treated with KPT-185 at respective IC50 doses or control DMSO for 36 hours. Data shown as mean percentage in G1 phase. Supplementary Figure 4. Combinatorial effects of KPT-185 and cisplatin in OvCa cells. Supplementary Figure 5. Knockdown of p53 by p53 siRNA blocked the KPT-mediated apoptosis in CP70 cells. Supplementary Figure 6. P53 network following KPT-185 treatment in CP70 cells. Supplementary Figure7. Representative images and mutation status of original human tumor pathology specimens and paired PDX tumor sections.</p>" @default.
• W4361923614 created "2023-04-05" @default.
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• W4361923614 date "2023-03-31" @default.
• W4361923614 modified "2023-10-16" @default.
• W4361923614 title "Supplementary Figures from Inhibition of the Nuclear Export Receptor XPO1 as a Therapeutic Target for Platinum-Resistant Ovarian Cancer" @default.
• W4361923614 doi "https://doi.org/10.1158/1078-0432.22464168.v1" @default.
• W4361923614 hasPublicationYear "2023" @default.
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