Matches in SemOpenAlex for { <https://semopenalex.org/work/W4361931570> ?p ?o ?g. }
Showing items 1 to 93 of
93
with 100 items per page.
- W4361931570 abstract "<p>Supplementary Fig. S2: Repertoire of somatic mutations found in the biopsies of primary breast cancers and their metastatic lesions in the nine treatment-naïve patients with de novo synchronous metastatic breast cancer. (A) Heatmaps indicate the cancer cell fraction of somatic mutations as determined by ABSOLUTE (24) (blue, see color key) or their absence (grey) in each biopsy (frozen and FFPE where available). Clonal mutations are highlighted in orange boxes and mutations associated with the loss of the wild-type allele are indicated with a diagonal bar. Red, dark grey and light grey dots beneath the heatmap indicate the mutation pathogenicity according to the color key. Mutations affecting cancer genes (31-33) are indicated by orange dots. Cases are grouped according to their ER and HER2 status. (B) Barplots of the distribution of mutations (top) present and (bottom) clonal in the frozen and FFPE diagnostic biopsies of the paired primary tumors and the metastatic lesions, classified as likely pathogenic (cancer genes), likely pathogenic (other genes), of indeterminate pathogenicity, likely passenger and synonymous mutations from all patients. Comparisons between the groups of mutations of different pathogenicity were performed using Fisher's exact tests. *: p < 0.05, **: p < 0.01, ***: p < 0.001, ns: not significant.</p>" @default.
- W4361931570 created "2023-04-05" @default.
- W4361931570 creator A5003635959 @default.
- W4361931570 creator A5005286764 @default.
- W4361931570 creator A5013503475 @default.
- W4361931570 creator A5015202957 @default.
- W4361931570 creator A5016638133 @default.
- W4361931570 creator A5022695298 @default.
- W4361931570 creator A5029484872 @default.
- W4361931570 creator A5034058277 @default.
- W4361931570 creator A5037340510 @default.
- W4361931570 creator A5039225060 @default.
- W4361931570 creator A5040506127 @default.
- W4361931570 creator A5051087530 @default.
- W4361931570 creator A5052303092 @default.
- W4361931570 creator A5055884560 @default.
- W4361931570 creator A5057848295 @default.
- W4361931570 creator A5065067520 @default.
- W4361931570 creator A5077235697 @default.
- W4361931570 creator A5078038241 @default.
- W4361931570 date "2023-03-31" @default.
- W4361931570 modified "2023-09-26" @default.
- W4361931570 title "Supplementary Figure S2 from Genetic Heterogeneity in Therapy-Naïve Synchronous Primary Breast Cancers and Their Metastases" @default.
- W4361931570 doi "https://doi.org/10.1158/1078-0432.22468661.v1" @default.
- W4361931570 hasPublicationYear "2023" @default.
- W4361931570 type Work @default.
- W4361931570 citedByCount "0" @default.
- W4361931570 crossrefType "posted-content" @default.
- W4361931570 hasAuthorship W4361931570A5003635959 @default.
- W4361931570 hasAuthorship W4361931570A5005286764 @default.
- W4361931570 hasAuthorship W4361931570A5013503475 @default.
- W4361931570 hasAuthorship W4361931570A5015202957 @default.
- W4361931570 hasAuthorship W4361931570A5016638133 @default.
- W4361931570 hasAuthorship W4361931570A5022695298 @default.
- W4361931570 hasAuthorship W4361931570A5029484872 @default.
- W4361931570 hasAuthorship W4361931570A5034058277 @default.
- W4361931570 hasAuthorship W4361931570A5037340510 @default.
- W4361931570 hasAuthorship W4361931570A5039225060 @default.
- W4361931570 hasAuthorship W4361931570A5040506127 @default.
- W4361931570 hasAuthorship W4361931570A5051087530 @default.
- W4361931570 hasAuthorship W4361931570A5052303092 @default.
- W4361931570 hasAuthorship W4361931570A5055884560 @default.
- W4361931570 hasAuthorship W4361931570A5057848295 @default.
- W4361931570 hasAuthorship W4361931570A5065067520 @default.
- W4361931570 hasAuthorship W4361931570A5077235697 @default.
- W4361931570 hasAuthorship W4361931570A5078038241 @default.
- W4361931570 hasBestOaLocation W43619315701 @default.
- W4361931570 hasConcept C104317684 @default.
- W4361931570 hasConcept C121608353 @default.
- W4361931570 hasConcept C127716648 @default.
- W4361931570 hasConcept C142724271 @default.
- W4361931570 hasConcept C180754005 @default.
- W4361931570 hasConcept C2781187634 @default.
- W4361931570 hasConcept C501734568 @default.
- W4361931570 hasConcept C502942594 @default.
- W4361931570 hasConcept C530470458 @default.
- W4361931570 hasConcept C54355233 @default.
- W4361931570 hasConcept C64618202 @default.
- W4361931570 hasConcept C71924100 @default.
- W4361931570 hasConcept C86803240 @default.
- W4361931570 hasConceptScore W4361931570C104317684 @default.
- W4361931570 hasConceptScore W4361931570C121608353 @default.
- W4361931570 hasConceptScore W4361931570C127716648 @default.
- W4361931570 hasConceptScore W4361931570C142724271 @default.
- W4361931570 hasConceptScore W4361931570C180754005 @default.
- W4361931570 hasConceptScore W4361931570C2781187634 @default.
- W4361931570 hasConceptScore W4361931570C501734568 @default.
- W4361931570 hasConceptScore W4361931570C502942594 @default.
- W4361931570 hasConceptScore W4361931570C530470458 @default.
- W4361931570 hasConceptScore W4361931570C54355233 @default.
- W4361931570 hasConceptScore W4361931570C64618202 @default.
- W4361931570 hasConceptScore W4361931570C71924100 @default.
- W4361931570 hasConceptScore W4361931570C86803240 @default.
- W4361931570 hasLocation W43619315701 @default.
- W4361931570 hasLocation W43619315702 @default.
- W4361931570 hasLocation W43619315703 @default.
- W4361931570 hasLocation W43619315704 @default.
- W4361931570 hasLocation W43619315705 @default.
- W4361931570 hasOpenAccess W4361931570 @default.
- W4361931570 hasPrimaryLocation W43619315701 @default.
- W4361931570 hasRelatedWork W1599368627 @default.
- W4361931570 hasRelatedWork W2013166796 @default.
- W4361931570 hasRelatedWork W2034211922 @default.
- W4361931570 hasRelatedWork W2044992835 @default.
- W4361931570 hasRelatedWork W2057739827 @default.
- W4361931570 hasRelatedWork W2070922469 @default.
- W4361931570 hasRelatedWork W2143066563 @default.
- W4361931570 hasRelatedWork W2157166663 @default.
- W4361931570 hasRelatedWork W2223919059 @default.
- W4361931570 hasRelatedWork W4248183732 @default.
- W4361931570 isParatext "false" @default.
- W4361931570 isRetracted "false" @default.
- W4361931570 workType "article" @default.