Matches in SemOpenAlex for { <https://semopenalex.org/work/W4361940419> ?p ?o ?g. }
Showing items 1 to 89 of
89
with 100 items per page.
- W4361940419 abstract "<p>Fig. S1: BTK mutations detected in cDNA in five FL BTK mutant cases. Fig. S2:BTK mutations destabilize the mutant BTK proteins. Fig. S3:BTK mutations do not influence PLCγ2-1217 phosphorylation in reconstituted lymphoma cell lines. Fig. S4:BTK mutations do not influence PLCγ2-759 phosphorylation in reconstituted lymphoma cell lines Fig. S5:Preserved PLCγ2-1217 phosphorylation in OCI-LY7 BTK-/- BLK-/- cells. Fig. S6:PLCγ2-1217 or PLCγ2-759 phosphorylation in OCI-LY7 BTK-/- BLK-/- or SUDHL4 BTK-/- BLK-/- cells treated with kinase inhibitors. Fig. S7:BTK mutations enhance anti-IgM induced AKT308 phosphorylation Fig. S8: Acute inhibition of BTK by ibrutinib or acalabrutinib does not augment anti-Ig induced AKT phosphorylation Fig. S9: The proteolysis targeting chimera (PROTAC)-mediated degradation of BTK protein results in augmentation of sIG-crosslinking induced AKT phosphorylation. Fig. S10:Primary human FL B cells have augmented AKT phosphorylation following surface IgM crosslinking: Fig. S11: The augmented phosphorylation of AKT by BTK mutants following anti-Ig treatment is abolished by pre-treatment with a PI3KÎ' inhibitor (CAL101) Fig. S12: Effects of BTK mutations on ibrutinib sensitivities in HBL1 and TMD8 cell lines</p>" @default.
- W4361940419 created "2023-04-05" @default.
- W4361940419 creator A5002639476 @default.
- W4361940419 creator A5013707598 @default.
- W4361940419 creator A5017947172 @default.
- W4361940419 creator A5030086195 @default.
- W4361940419 creator A5035081675 @default.
- W4361940419 creator A5044883230 @default.
- W4361940419 creator A5062534813 @default.
- W4361940419 creator A5065543394 @default.
- W4361940419 creator A5073754378 @default.
- W4361940419 creator A5080366682 @default.
- W4361940419 creator A5081678576 @default.
- W4361940419 creator A5085727557 @default.
- W4361940419 date "2023-03-31" @default.
- W4361940419 modified "2023-10-18" @default.
- W4361940419 title "Supplementary Figures 1-12 and Tables S1-S2 from Follicular Lymphoma–associated BTK Mutations are Inactivating Resulting in Augmented AKT Activation" @default.
- W4361940419 doi "https://doi.org/10.1158/1078-0432.22483716.v1" @default.
- W4361940419 hasPublicationYear "2023" @default.
- W4361940419 type Work @default.
- W4361940419 citedByCount "0" @default.
- W4361940419 crossrefType "posted-content" @default.
- W4361940419 hasAuthorship W4361940419A5002639476 @default.
- W4361940419 hasAuthorship W4361940419A5013707598 @default.
- W4361940419 hasAuthorship W4361940419A5017947172 @default.
- W4361940419 hasAuthorship W4361940419A5030086195 @default.
- W4361940419 hasAuthorship W4361940419A5035081675 @default.
- W4361940419 hasAuthorship W4361940419A5044883230 @default.
- W4361940419 hasAuthorship W4361940419A5062534813 @default.
- W4361940419 hasAuthorship W4361940419A5065543394 @default.
- W4361940419 hasAuthorship W4361940419A5073754378 @default.
- W4361940419 hasAuthorship W4361940419A5080366682 @default.
- W4361940419 hasAuthorship W4361940419A5081678576 @default.
- W4361940419 hasAuthorship W4361940419A5085727557 @default.
- W4361940419 hasBestOaLocation W43619404191 @default.
- W4361940419 hasConcept C104317684 @default.
- W4361940419 hasConcept C11960822 @default.
- W4361940419 hasConcept C143065580 @default.
- W4361940419 hasConcept C153911025 @default.
- W4361940419 hasConcept C185592680 @default.
- W4361940419 hasConcept C203014093 @default.
- W4361940419 hasConcept C2777938653 @default.
- W4361940419 hasConcept C2778461978 @default.
- W4361940419 hasConcept C2779878957 @default.
- W4361940419 hasConcept C42362537 @default.
- W4361940419 hasConcept C502942594 @default.
- W4361940419 hasConcept C55493867 @default.
- W4361940419 hasConcept C62478195 @default.
- W4361940419 hasConcept C75217442 @default.
- W4361940419 hasConcept C86554907 @default.
- W4361940419 hasConcept C86803240 @default.
- W4361940419 hasConcept C90059517 @default.
- W4361940419 hasConcept C95444343 @default.
- W4361940419 hasConceptScore W4361940419C104317684 @default.
- W4361940419 hasConceptScore W4361940419C11960822 @default.
- W4361940419 hasConceptScore W4361940419C143065580 @default.
- W4361940419 hasConceptScore W4361940419C153911025 @default.
- W4361940419 hasConceptScore W4361940419C185592680 @default.
- W4361940419 hasConceptScore W4361940419C203014093 @default.
- W4361940419 hasConceptScore W4361940419C2777938653 @default.
- W4361940419 hasConceptScore W4361940419C2778461978 @default.
- W4361940419 hasConceptScore W4361940419C2779878957 @default.
- W4361940419 hasConceptScore W4361940419C42362537 @default.
- W4361940419 hasConceptScore W4361940419C502942594 @default.
- W4361940419 hasConceptScore W4361940419C55493867 @default.
- W4361940419 hasConceptScore W4361940419C62478195 @default.
- W4361940419 hasConceptScore W4361940419C75217442 @default.
- W4361940419 hasConceptScore W4361940419C86554907 @default.
- W4361940419 hasConceptScore W4361940419C86803240 @default.
- W4361940419 hasConceptScore W4361940419C90059517 @default.
- W4361940419 hasConceptScore W4361940419C95444343 @default.
- W4361940419 hasLocation W43619404191 @default.
- W4361940419 hasLocation W43619404192 @default.
- W4361940419 hasLocation W43619404193 @default.
- W4361940419 hasOpenAccess W4361940419 @default.
- W4361940419 hasPrimaryLocation W43619404191 @default.
- W4361940419 hasRelatedWork W1780111622 @default.
- W4361940419 hasRelatedWork W1794509960 @default.
- W4361940419 hasRelatedWork W1830209188 @default.
- W4361940419 hasRelatedWork W2028681024 @default.
- W4361940419 hasRelatedWork W2059968417 @default.
- W4361940419 hasRelatedWork W2154945466 @default.
- W4361940419 hasRelatedWork W2197292765 @default.
- W4361940419 hasRelatedWork W2789446032 @default.
- W4361940419 hasRelatedWork W4378591451 @default.
- W4361940419 hasRelatedWork W4385971005 @default.
- W4361940419 isParatext "false" @default.
- W4361940419 isRetracted "false" @default.
- W4361940419 workType "article" @default.