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- W4361948300 abstract "<div>Abstract<p><b>Background:</b> Potential harms of screening mammography include false positive results, such as recall breast imaging or biopsies.</p><p><b>Methods:</b> We recruited women undergoing screening mammography at Columbia University Medical Center in New York, New York. They completed a questionnaire on breast cancer risk factors and permitted access to their medical records. Breast cancer risk status was determined using the Gail model and a family history screener. High risk was defined as a 5-year invasive breast cancer risk of ≥1.67% or eligible for <i>BRCA</i> genetic testing. False positive results were defined as recall breast imaging (BIRADS score of 0, 3, 4, or 5) and/or biopsies that did not yield breast cancer.</p><p><b>Results:</b> From November 2014 to October 2015, 2,361 women were enrolled and 2,019 were evaluable, of whom 76% were Hispanic and 10% non-Hispanic white. Fewer Hispanic women met high-risk criteria for breast cancer than non-Hispanic whites (18.0% vs. 68.1%), but Hispanics more frequently engaged in annual screening (71.9% vs. 60.8%). Higher breast density (heterogeneously/extremely dense vs. mostly fat/scattered fibroglandular densities) and more frequent screening (annual vs. biennial) were significantly associated with false positive results [odds ratio (OR), 1.64; 95% confidence interval (CI), 1.32–2.04 and OR, 2.18; 95% CI, 1.70–2.80, respectively].</p><p><b>Conclusions:</b> We observed that women who screened more frequently or had higher breast density were at greater risk for false positive results. In addition, Hispanic women were screening more frequently despite having a lower risk of breast cancer compared with whites.</p><p><b>Impact:</b> Our results highlight the need for risk-stratified screening to potentially minimize the harms of screening mammography. <i>Cancer Epidemiol Biomarkers Prev; 27(4); 446–53. ©2018 AACR</i>.</p></div>" @default.
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- W4361948300 date "2023-03-31" @default.
- W4361948300 modified "2023-09-26" @default.
- W4361948300 title "Data from Factors Associated with False Positive Results on Screening Mammography in a Population of Predominantly Hispanic Women" @default.
- W4361948300 doi "https://doi.org/10.1158/1055-9965.c.6516277.v1" @default.
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