FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4361989159> ?p ?o ?g. }

• W4361989159 abstract "Prevention of mother-to-child transmission (PMTCT) programs for hepatitis B virus (HBV) are critical to reach the World Health Organization's 2030 HBV elimination goals. Despite demonstrated feasibility utilizing HIV infrastructure, HBV PMTCT programs are not implemented in many African settings, including in the Democratic Republic of Congo (DRC). In a previous pilot of HBV PMTCT implementation in DRC's capital, Kinshasa, we observed low TDF metabolite levels at delivery among women with high-risk HBV who were given tenofovir disoproxil fumarate (TDF) antiviral therapy. As such, we conducted qualitative interviews with women who received TDF to understand facilitators and barriers of medication adherence. We used a modified Information-Motivation-Behavioral Skills model (IMB+) as a framework for thematic content analysis. We found that trust in healthcare workers, familial support, and improved awareness of the disease and treatment options were important facilitators of TDF adherence; pill size, social stigma, and low HBV knowledge were barriers to adherence. While overall acceptance of TDF was high in this pilot, improved TDF adherence is needed in order to reach efficacious levels for preventing transmission from mothers to newborns. We suggest ongoing HBV sensitization within existing maternity and HIV care infrastructure would address gaps in knowledge and stigma identified here. Additionally, given the trust women have towards maternity center staff and volunteers, scaled HBV PMTCT interventions should include specific sensitization and education for healthcare affiliates, who currently receive no HBV prevention or information in DRC. This study is timely as TDF, particularly future long-acting formulations, could be considered as an alternate rather than adjuvant to birth-dose vaccination for HBV PMTCT in sub-Saharan Africa." @default.
• W4361989159 created "2023-04-05" @default.
• W4361989159 creator A5011538531 @default.
• W4361989159 creator A5020242502 @default.
• W4361989159 creator A5020260613 @default.
• W4361989159 creator A5020479270 @default.
• W4361989159 creator A5023171162 @default.
• W4361989159 creator A5027740084 @default.
• W4361989159 creator A5040445622 @default.
• W4361989159 creator A5040840632 @default.
• W4361989159 creator A5043555364 @default.
• W4361989159 creator A5052393417 @default.
• W4361989159 creator A5069654287 @default.
• W4361989159 creator A5071521824 @default.
• W4361989159 creator A5089410659 @default.
• W4361989159 date "2023-03-31" @default.
• W4361989159 modified "2023-09-27" @default.
• W4361989159 title "Participant perspectives to improve tenofovir adherence in the prevention of mother-to-child transmission of hepatitis B virus in Kinshasa, DRC" @default.
• W4361989159 cites W1502059937 @default.
• W4361989159 cites W1508639755 @default.
• W4361989159 cites W1964052047 @default.
• W4361989159 cites W1976859317 @default.
• W4361989159 cites W1978624695 @default.
• W4361989159 cites W1980327212 @default.
• W4361989159 cites W1981701419 @default.
• W4361989159 cites W1988231072 @default.
• W4361989159 cites W2012181079 @default.
• W4361989159 cites W2039555502 @default.
• W4361989159 cites W2062097741 @default.
• W4361989159 cites W2073168719 @default.
• W4361989159 cites W2080415332 @default.
• W4361989159 cites W2116026933 @default.
• W4361989159 cites W2132284513 @default.
• W4361989159 cites W2155441883 @default.
• W4361989159 cites W2520996611 @default.
• W4361989159 cites W2562073418 @default.
• W4361989159 cites W2597747925 @default.
• W4361989159 cites W2619447654 @default.
• W4361989159 cites W2746562707 @default.
• W4361989159 cites W2789369329 @default.
• W4361989159 cites W2790550357 @default.
• W4361989159 cites W2793540847 @default.
• W4361989159 cites W2799995545 @default.
• W4361989159 cites W2901032280 @default.
• W4361989159 cites W2902217860 @default.
• W4361989159 cites W2903602359 @default.
• W4361989159 cites W2910259673 @default.
• W4361989159 cites W2918073261 @default.
• W4361989159 cites W2935778331 @default.
• W4361989159 cites W2944306902 @default.
• W4361989159 cites W2972616577 @default.
• W4361989159 cites W2981440925 @default.
• W4361989159 cites W3003419751 @default.
• W4361989159 cites W3030394439 @default.
• W4361989159 cites W3043669843 @default.
• W4361989159 cites W3196157093 @default.
• W4361989159 cites W4297901154 @default.
• W4361989159 doi "https://doi.org/10.1101/2023.03.30.23287808" @default.
• W4361989159 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37034729" @default.
• W4361989159 hasPublicationYear "2023" @default.
• W4361989159 type Work @default.
• W4361989159 citedByCount "0" @default.
• W4361989159 crossrefType "posted-content" @default.
• W4361989159 hasAuthorship W4361989159A5011538531 @default.
• W4361989159 hasAuthorship W4361989159A5020242502 @default.
• W4361989159 hasAuthorship W4361989159A5020260613 @default.
• W4361989159 hasAuthorship W4361989159A5020479270 @default.
• W4361989159 hasAuthorship W4361989159A5023171162 @default.
• W4361989159 hasAuthorship W4361989159A5027740084 @default.
• W4361989159 hasAuthorship W4361989159A5040445622 @default.
• W4361989159 hasAuthorship W4361989159A5040840632 @default.
• W4361989159 hasAuthorship W4361989159A5043555364 @default.
• W4361989159 hasAuthorship W4361989159A5052393417 @default.
• W4361989159 hasAuthorship W4361989159A5069654287 @default.
• W4361989159 hasAuthorship W4361989159A5071521824 @default.
• W4361989159 hasAuthorship W4361989159A5089410659 @default.
• W4361989159 hasBestOaLocation W43619891591 @default.
• W4361989159 hasConcept C118552586 @default.
• W4361989159 hasConcept C119599485 @default.
• W4361989159 hasConcept C127413603 @default.
• W4361989159 hasConcept C144024400 @default.
• W4361989159 hasConcept C159110408 @default.
• W4361989159 hasConcept C168285401 @default.
• W4361989159 hasConcept C190248442 @default.
• W4361989159 hasConcept C203014093 @default.
• W4361989159 hasConcept C2522874641 @default.
• W4361989159 hasConcept C27415008 @default.
• W4361989159 hasConcept C2777382497 @default.
• W4361989159 hasConcept C2780593183 @default.
• W4361989159 hasConcept C2781437451 @default.
• W4361989159 hasConcept C3013748606 @default.
• W4361989159 hasConcept C36289849 @default.
• W4361989159 hasConcept C512399662 @default.
• W4361989159 hasConcept C71924100 @default.
• W4361989159 hasConcept C74196892 @default.
• W4361989159 hasConcept C761482 @default.
• W4361989159 hasConceptScore W4361989159C118552586 @default.
• W4361989159 hasConceptScore W4361989159C119599485 @default.
• W4361989159 hasConceptScore W4361989159C127413603 @default.
• W4361989159 hasConceptScore W4361989159C144024400 @default.

• next