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• W4362072190 abstract "No AccessJournal of UrologyCLINICAL UROLOGY: Original Articles1 Dec 2001HOW DO PATIENTS WITH INTERSTITIAL CYSTITIS PRESENT? ALISA DRISCOLL and JOEL M.H. TEICHMAN ALISA DRISCOLLALISA DRISCOLL More articles by this author and JOEL M.H. TEICHMANJOEL M.H. TEICHMAN More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(05)65517-6AboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract Purpose: We determined how interstitial cystitis progresses from initial symptoms to diagnosis. Materials and Methods: We retrospectively analyzed the records of 45 patients to determine the dates of symptom onset and diagnosis, and sequence of urgency/frequency, nocturia and pain. We also documented alternate and previous diagnoses, and previous surgical treatments. Results: Of the patients 89% presented with only 1 symptom. Median time from the initial symptom to all symptoms was 2 years (mean 5.5). The most common previous diagnoses were urinary infection in 19 cases, a gynecologic diagnosis in 14 and urethral diagnoses in 6. A previous urinary infection was documented in only 1 of 19 patients, while 11 had undergone hysterectomy and 5 diagnosed with endometriosis had no pathological documentation available. Conclusions: Early interstitial cystitis presents variably and usually with only a single symptom of urgency/frequency, nocturia or pain. Clinicians may fail to appreciate the symptoms of early interstitial cystitis, which leads to delayed diagnosis until the patient is more symptomatic. With time multiple symptoms manifest. Bacterial cystitis, prostatitis, endometriosis and chronic pelvic pain are common initial misdiagnoses. Interstitial cystitis should be considered when laboratory documentation of alternate diagnoses is lacking or when patients fail to respond to therapy for alternate diagnoses. 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Google Scholar From the Division of Urology, University of Texas Health Science Center-San Antonio, San Antonio, Texas© 2001 by American Urological Association, Inc.FiguresReferencesRelatedDetailsCited byHanno P, Erickson D, Moldwin R and Faraday M (2018) Diagnosis and Treatment of Interstitial Cystitis/Bladder Pain Syndrome: AUA Guideline AmendmentJournal of Urology, VOL. 193, NO. 5, (1545-1553), Online publication date: 1-May-2015.Lai H, Vetter J, Jain S, Gereau R and Andriole G (2018) The Overlap and Distinction of Self-Reported Symptoms between Interstitial Cystitis/Bladder Pain Syndrome and Overactive Bladder: A Questionnaire Based AnalysisJournal of Urology, VOL. 192, NO. 6, (1679-1686), Online publication date: 1-Dec-2014.Teichman J (2018) New Treatments for Painful Urological ConditionsJournal of Urology, VOL. 189, NO. 2, (415-416), Online publication date: 1-Feb-2013.Nickel J, Crossland A, Davis E, Haab F, Mills I, Rovner E, Scholfield D and Crook T (2018) Investigation of a Ca2+ Channel α2δ Ligand for the Treatment of Interstitial Cystitis: Results of a Randomized, Double-Blind, Placebo Controlled Phase II TrialJournal of Urology, VOL. 188, NO. 3, (817-823), Online publication date: 1-Sep-2012.Evans R, Moldwin R, Cossons N, Darekar A, Mills I and Scholfield D (2018) Proof of Concept Trial of Tanezumab for the Treatment of Symptoms Associated With Interstitial CystitisJournal of Urology, VOL. 185, NO. 5, (1716-1721), Online publication date: 1-May-2011.Hanno P, Burks D, Clemens J, Dmochowski R, Erickson D, FitzGerald M, Forrest J, Gordon B, Gray M, Mayer R, Newman D, Nyberg L, Payne C, Wesselmann U and Faraday M (2018) AUA Guideline for the Diagnosis and Treatment of Interstitial Cystitis/Bladder Pain SyndromeJournal of Urology, VOL. 185, NO. 6, (2162-2170), Online publication date: 1-Jun-2011.Seth A and Teichman J (2018) Differences in the Clinical Presentation of Interstitial Cystitis/Painful Bladder Syndrome in Patients With or Without Sexual Abuse HistoryJournal of Urology, VOL. 180, NO. 5, (2029-2033), Online publication date: 1-Nov-2008.Bogart L, Berry S and Clemens J (2018) Symptoms of Interstitial Cystitis, Painful Bladder Syndrome and Similar Diseases in Women: A Systematic ReviewJournal of Urology, VOL. 177, NO. 2, (450-456), Online publication date: 1-Feb-2007.ROSENBERG M and HAZZARD M (2018) PREVALENCE OF INTERSTITIAL CYSTITIS SYMPTOMS IN WOMEN: A POPULATION BASED STUDY IN THE PRIMARY CARE OFFICEJournal of Urology, VOL. 174, NO. 6, (2231-2234), Online publication date: 1-Dec-2005.DAHA L, RIEDL C, HOHLBRUGGER G, KNOLL M, ENGELHARDT P and PFLÜGER H (2018) Comparative Assessment of Maximal Bladder Capacity, 0.9% NaCl Versus 0.2 M Kcl, for the Diagnosis of Interstitial Cystitis: A Prospective Controlled StudyJournal of Urology, VOL. 170, NO. 3, (807-809), Online publication date: 1-Sep-2003. Volume 166Issue 6December 2001Page: 2118-2120 Advertisement Copyright & Permissions© 2001 by American Urological Association, Inc.Keywordscystitis, interstitialsigns and symptomsbladderdiagnosis, differentialMetricsAuthor Information ALISA DRISCOLL More articles by this author JOEL M.H. TEICHMAN More articles by this author Expand All Advertisement PDF downloadLoading ..." @default.
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