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- W4362242584 abstract "<p>Supplementary Tables S1-S6. Primers used in this study (S1); The statistics for the final water-refined set of NMR structures of IBD-MLL 140-160 complex (S2); The solvent-accessible surface area (BSA) of individual lBD residues buried upon IBD-HIV1-integrase (HIV IN) or IBD-MLL complex formation is expressed as a portion of the residue total solvent accessible area (BSA in %). The BSA was calculated using PDBePISA tool (S3); Effect of LEDGF/p75 mutations on the interaction with MLL as measured by AlphaScreen (S4); Effect of LEDGF/p75 mutations defective for binding to HIV-1 integrase on the interaction with MLL as measured by AlphaScreen (S5); Melting temperatures of the PWWP and IBD domain of wild type LEDGF/p75 or its mutants as determined by DSF (S6).</p>" @default.
- W4362242584 created "2023-04-05" @default.
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- W4362242584 date "2023-03-30" @default.
- W4362242584 modified "2023-10-18" @default.
- W4362242584 title "Data Supplement from Validation and Structural Characterization of the LEDGF/p75–MLL Interface as a New Target for the Treatment of MLL-Dependent Leukemia" @default.
- W4362242584 doi "https://doi.org/10.1158/0008-5472.22403316" @default.
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