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- W4362393062 abstract "<p>PDF file - 757KB, Effect of the cell growth and the intracellular signals by BGT226. (A) Growth inhibitory effect of BGT226, rapamycin and LY294002. FaDu and OECM1 cells were treated with each compound in the identical concentration-dependent manner. The result was plotted (X axis, logarithm scale of concentration; y axis, ratio). (B) Effect of BGT226 and the other PI3K/mTOR targeting agents in OECM1. In the left panel, cells were treated with BGT226 120 nM or LY294002 2μM in a time-dependent manner. In the right panel, cells were treated with various PI3K/mTOR targeting agents for 30 min before whole cell lysate collection (G, BGT226 120 nM; K, BKM120 2μM; Rad, RAD001, 0.5 or 2 nM; L, LY294002 2μM; Rapa, rapamycin 100 or 200 nM; C, control).</p>" @default.
- W4362393062 created "2023-04-05" @default.
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- W4362393062 date "2023-03-31" @default.
- W4362393062 modified "2023-09-29" @default.
- W4362393062 title "Supplementary Figure 1 from Novel Phosphoinositide 3-Kinase/mTOR Dual Inhibitor, NVP-BGT226, Displays Potent Growth-Inhibitory Activity against Human Head and Neck Cancer Cells <i>In Vitro</i> and <i>In Vivo</i>" @default.
- W4362393062 doi "https://doi.org/10.1158/1078-0432.22443513" @default.
- W4362393062 hasPublicationYear "2023" @default.
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