Matches in SemOpenAlex for { <https://semopenalex.org/work/W4362457708> ?p ?o ?g. }
Showing items 1 to 95 of
95
with 100 items per page.
- W4362457708 endingPage "1291" @default.
- W4362457708 startingPage "1283" @default.
- W4362457708 abstract "Although acute upper gastrointestinal bleeding (UGIB) can lead to anemia, evidence regarding the effects of oral iron supplementation on UGIB-induced anemia following discharge remains lacking. The present study aimed to investigate the effects of oral iron supplementation on hemoglobin response and iron storage in patients with anemia secondary to nonvariceal UGIB.This randomized controlled trial included 151 patients with nonvariceal UGIB who had anemia at discharge. Patients were assigned to a 1:1 block in which they were either administered 6 weeks of 600 mg/d oral ferrous fumarate (treatment group, n = 77) or treated without iron supplementation (control group, n = 74). The primary outcome was composite hemoglobin response (hemoglobin elevation greater than 2 g/dL or no anemia at the end of treatment [EOT]).The proportion of patients achieving composite hemoglobin response was greater in the treatment group than in the control group (72.7% vs 45.9%; adjusted risk ratio [RR], 2.980; P = 0.004). At EOT, the percentage change in the hemoglobin level (34.2 ± 24.8% vs 19.4 ± 19.9%; adjusted coefficient, 11.543; P < 0.001) was significantly higher in the treatment group than in the control group; however, the proportions of patients with a serum ferritin level <30 μg/L and a transferrin saturation <16% were lower in the treatment group (all P < 0.05). No significant differences in treatment-associated adverse effects and adherence rates were observed between the groups.Oral iron supplementation exerts beneficial effects on anemia and iron storage following nonvariceal UGIB without significantly impacting rates of adverse effects or adherence." @default.
- W4362457708 created "2023-04-05" @default.
- W4362457708 creator A5003771923 @default.
- W4362457708 creator A5008651025 @default.
- W4362457708 creator A5010955427 @default.
- W4362457708 creator A5033859481 @default.
- W4362457708 creator A5061066775 @default.
- W4362457708 creator A5071209881 @default.
- W4362457708 creator A5078675022 @default.
- W4362457708 creator A5082910778 @default.
- W4362457708 date "2023-04-06" @default.
- W4362457708 modified "2023-10-17" @default.
- W4362457708 title "Role of oral iron supplementation for anemia secondary to acute nonvariceal upper gastrointestinal bleeding: a randomized controlled trial" @default.
- W4362457708 cites W1895764000 @default.
- W4362457708 cites W2003087388 @default.
- W4362457708 cites W2010799033 @default.
- W4362457708 cites W2032388920 @default.
- W4362457708 cites W2036925949 @default.
- W4362457708 cites W2053553705 @default.
- W4362457708 cites W2075011412 @default.
- W4362457708 cites W2100001962 @default.
- W4362457708 cites W2114614290 @default.
- W4362457708 cites W2141357797 @default.
- W4362457708 cites W2147368252 @default.
- W4362457708 cites W2149142252 @default.
- W4362457708 cites W2149589895 @default.
- W4362457708 cites W2219775147 @default.
- W4362457708 cites W2316953849 @default.
- W4362457708 cites W2519561299 @default.
- W4362457708 cites W2580061878 @default.
- W4362457708 cites W2799519829 @default.
- W4362457708 cites W2895896699 @default.
- W4362457708 cites W2951672937 @default.
- W4362457708 cites W2982000918 @default.
- W4362457708 cites W3030200688 @default.
- W4362457708 cites W3111656568 @default.
- W4362457708 cites W3157215120 @default.
- W4362457708 doi "https://doi.org/10.1111/jgh.16185" @default.
- W4362457708 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36999193" @default.
- W4362457708 hasPublicationYear "2023" @default.
- W4362457708 type Work @default.
- W4362457708 citedByCount "0" @default.
- W4362457708 crossrefType "journal-article" @default.
- W4362457708 hasAuthorship W4362457708A5003771923 @default.
- W4362457708 hasAuthorship W4362457708A5008651025 @default.
- W4362457708 hasAuthorship W4362457708A5010955427 @default.
- W4362457708 hasAuthorship W4362457708A5033859481 @default.
- W4362457708 hasAuthorship W4362457708A5061066775 @default.
- W4362457708 hasAuthorship W4362457708A5071209881 @default.
- W4362457708 hasAuthorship W4362457708A5078675022 @default.
- W4362457708 hasAuthorship W4362457708A5082910778 @default.
- W4362457708 hasBestOaLocation W43624577081 @default.
- W4362457708 hasConcept C126322002 @default.
- W4362457708 hasConcept C141071460 @default.
- W4362457708 hasConcept C153852466 @default.
- W4362457708 hasConcept C168563851 @default.
- W4362457708 hasConcept C2776732101 @default.
- W4362457708 hasConcept C2777417653 @default.
- W4362457708 hasConcept C2778248108 @default.
- W4362457708 hasConcept C2778319317 @default.
- W4362457708 hasConcept C2778917026 @default.
- W4362457708 hasConcept C71924100 @default.
- W4362457708 hasConcept C90924648 @default.
- W4362457708 hasConceptScore W4362457708C126322002 @default.
- W4362457708 hasConceptScore W4362457708C141071460 @default.
- W4362457708 hasConceptScore W4362457708C153852466 @default.
- W4362457708 hasConceptScore W4362457708C168563851 @default.
- W4362457708 hasConceptScore W4362457708C2776732101 @default.
- W4362457708 hasConceptScore W4362457708C2777417653 @default.
- W4362457708 hasConceptScore W4362457708C2778248108 @default.
- W4362457708 hasConceptScore W4362457708C2778319317 @default.
- W4362457708 hasConceptScore W4362457708C2778917026 @default.
- W4362457708 hasConceptScore W4362457708C71924100 @default.
- W4362457708 hasConceptScore W4362457708C90924648 @default.
- W4362457708 hasIssue "8" @default.
- W4362457708 hasLocation W43624577081 @default.
- W4362457708 hasLocation W43624577082 @default.
- W4362457708 hasOpenAccess W4362457708 @default.
- W4362457708 hasPrimaryLocation W43624577081 @default.
- W4362457708 hasRelatedWork W1878595794 @default.
- W4362457708 hasRelatedWork W2004200618 @default.
- W4362457708 hasRelatedWork W2057490347 @default.
- W4362457708 hasRelatedWork W2414193666 @default.
- W4362457708 hasRelatedWork W2560566517 @default.
- W4362457708 hasRelatedWork W2908540378 @default.
- W4362457708 hasRelatedWork W3025684670 @default.
- W4362457708 hasRelatedWork W3028893433 @default.
- W4362457708 hasRelatedWork W4292831968 @default.
- W4362457708 hasRelatedWork W2463185091 @default.
- W4362457708 hasVolume "38" @default.
- W4362457708 isParatext "false" @default.
- W4362457708 isRetracted "false" @default.
- W4362457708 workType "article" @default.