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- W4362481719 abstract "<p>PDF file - 402K, SFigure 1: Chemical structures of carfilzomib and obatoclax; SFigure 2: Co-treatment with carfilzomib and obatoclax synergistically induces cell death in SUDHL4 cells by Median Dose Effect analysis; SFigure 3: Combined treatment with carfilzomib and obatoclax fails to induce further NF- �B inactivation compared to single agent treatment in SUDHL4 and OCI-LY10 cells; SFigure 4: Co-exposure of SUDHL16 cells to carfilzomib and obatoclax diminishes the association between Mcl-1 and both Bak and Bim while triggering Bak and Bax activation; SFigure 5: Effects of combined treatment with carfilzomib and obatoclax on weight loss and WBC counts in an SUDHL4 xenograft model; SFigure 6: A schematic diagram depicting potential mechanisms underlying synergistic interaction between carfilzomib and obatoclax in DLBCL cells</p>" @default.
- W4362481719 created "2023-04-05" @default.
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- W4362481719 date "2023-04-03" @default.
- W4362481719 modified "2023-09-28" @default.
- W4362481719 title "Supplementary Figures 1-6 from Obatoclax Interacts Synergistically with the Irreversible Proteasome Inhibitor Carfilzomib in GC- and ABC-DLBCL Cells <i>In Vitro</i> and <i>In Vivo</i>" @default.
- W4362481719 doi "https://doi.org/10.1158/1535-7163.22497112" @default.
- W4362481719 hasPublicationYear "2023" @default.
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