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- W4362482009 abstract "<p>Supplementary Fig. S1: Characterization of the model used for whole genome silencing, individual screen lethality scores and list of candidate genes with differential lethality scores ; Supplementary Fig. S2: Validation of the RRM1 and RRM2 knockdown; Supplementary Fig. S3: Expression of RRM1 and RRM2 in MPM; Supplementary Fig. S4: Modulation of BAP1 expression, effect on gene expression, response to olaparib, and rescue of gemcitabine cytotoxicity by dNMPs; Supplementary Fig. S5: Schematic representation of the potential role of BAP1 in the regulation of RRM2 on transcriptional level under normal and replicative stress condition; Supplementary Fig. S6: Gemcitabine induced increase of RRM1 and RRM2 in NCI60 cell line panel and high RRM1 and RRM2 expression predicts poor overall survival in malignant pleural mesothelioma patients; Supplementary Table S1: Primer sequences; Supplementary Table S2: Gene ontology analysis on genes with differential lethality score.</p>" @default.
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- W4362482009 date "2023-04-03" @default.
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- W4362482009 title "Supplementary Data from Functional Genomic Screen in Mesothelioma Reveals that Loss of Function of BRCA1-Associated Protein 1 Induces Chemoresistance to Ribonucleotide Reductase Inhibition" @default.
- W4362482009 doi "https://doi.org/10.1158/1535-7163.22505877" @default.
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