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- W4362519962 startingPage "117043" @default.
- W4362519962 abstract "Brain tumor removal is a crucial step in therapeutic regimens. In surgical interventions, the ultimate goal is to completely resect the malignant lesion with a safe margin of healthy tissue; however, when the risk of impairing the patient's life functions is too high, the scope of such surgeries is often limited. Therefore, tools that can enable the accurate, specific, and sensitive differentiation of cancerous and non-cancerous tissue are needed. Furthermore, the ability to quickly assess lesion types or grades can also improve surgical outcomes. Measurable features of brain tumors can be obtained via histological imaging, genetic profiling, and metabolomic fingerprinting, which can be performed using a variety of analytical platforms. In recent years, optical, electrochemical, and mass-spectrometry-based probes have been modified for use in in vivo applications. Among these methods, mass-spectrometry-based methods have yielded the most promising results due to the number of approaches enabling real-time monitoring and tumor classification." @default.
- W4362519962 created "2023-04-06" @default.
- W4362519962 creator A5024735084 @default.
- W4362519962 creator A5044551220 @default.
- W4362519962 date "2023-05-01" @default.
- W4362519962 modified "2023-10-02" @default.
- W4362519962 title "Insight into new opportunities in intra-surgical diagnostics of brain tumors" @default.
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- W4362519962 doi "https://doi.org/10.1016/j.trac.2023.117043" @default.
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