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• W4362520554 abstract "Human microbiota demonstrate diversity and balance that is adaptive for the host and supports maintaining homeostasis. Although acute illness or injury may derange microbiota diversity and the proportion of potentially pathogenic microbes, that derangement may be further exacerbated by commonly deployed intensive care unit (ICU) therapeutic and practices. These include antibiotic administration, delayed luminal nutrition, acid suppression, and vasopressor infusion. Furthermore, the local ICU microbial ecology, regardless of disinfection practices, shapes the patient's microbiota, especially with the acquisition of multi-drug–resistant pathogens. Current approaches to protect a normal microbiome, or restore a deranged one, are part of a multifaceted approach that may include antibiotic stewardship and infection control practices as microbiome-directed therapeutics emerge." @default.
• W4362520554 created "2023-04-06" @default.
• W4362520554 creator A5085685364 @default.
• W4362520554 date "2023-04-01" @default.
• W4362520554 modified "2023-10-17" @default.
• W4362520554 title "Host Microbiome Threats in the Intensive Care Unit" @default.
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• W4362520554 doi "https://doi.org/10.1089/sur.2023.029" @default.
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