FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4362520779> ?p ?o ?g. }

• W4362520779 endingPage "868" @default.
• W4362520779 startingPage "861" @default.
• W4362520779 abstract "The lack of oestrogen receptor, progesterone receptor and human epidermal growth factor receptor-2 expression in breast cancer (BC) is the basis for the categorization of the tumour as triple negative breast carcinoma (TNBC). The majority of TNBCs are aggressive tumours with common metastases and decreased expression of markers that could help in identifying the metastatic lesion as of mammary origin. Breast markers, such as gross cystic disease fluid protein-15 (GCDPF-15), GATA binding protein 3 (GATA3), mammaglobin (MGB) and SOX10, are not uniquely specific to BC. Our aim was to evaluate trichorhinophalangeal syndrome type 1 (TRPS1) protein as a breast marker in a series of cytokeratin-5-expressing TNBC, mostly corresponding to basal-like TNBCs, previously characterized for the expression of other breast markers. One hundred seventeen TNBCs in tissue microarrays were immunostained for TRPS1. The cut-off for positivity was ≥ 10%. The reproducibility of this classification was also assessed. TRPS1 positivity was detected in 92/117 (79%) cases, and this exceeded the expression of previously tested markers like SOX10 82 (70%), GATA3 11 (9%), MGB 10 (9%) and GCDFP-15 7 (6%). Of the 25 TRPS1-negative cases, 11 were positive with SOX10, whereas 5 to 6 dual negatives displayed positivity for the other makers. The evaluation showed substantial agreement. Of the five markers compared, TRPS1 seems the most sensitive marker for the mammary origin of CK5-expressing TNBCs. Cases that are negative are most often labelled with SOX10, and the remainder may still demonstrate positivity for any of the 3 other markers. TRPS1 has a place in breast marker panels." @default.
• W4362520779 created "2023-04-06" @default.
• W4362520779 creator A5034025853 @default.
• W4362520779 creator A5051207413 @default.
• W4362520779 creator A5053906317 @default.
• W4362520779 creator A5056308350 @default.
• W4362520779 creator A5068440444 @default.
• W4362520779 creator A5070525371 @default.
• W4362520779 creator A5081877908 @default.
• W4362520779 date "2023-04-03" @default.
• W4362520779 modified "2023-09-26" @default.
• W4362520779 title "TRPS1 expression in cytokeratin 5 expressing triple negative breast cancers, its value as a marker of breast origin" @default.
• W4362520779 cites W1530437552 @default.
• W4362520779 cites W1977225846 @default.
• W4362520779 cites W1997592319 @default.
• W4362520779 cites W2035435944 @default.
• W4362520779 cites W2037033919 @default.
• W4362520779 cites W2044702943 @default.
• W4362520779 cites W2050737668 @default.
• W4362520779 cites W2053163855 @default.
• W4362520779 cites W2066985179 @default.
• W4362520779 cites W2074822115 @default.
• W4362520779 cites W2097255042 @default.
• W4362520779 cites W2099335989 @default.
• W4362520779 cites W2102096219 @default.
• W4362520779 cites W2131994307 @default.
• W4362520779 cites W2134539328 @default.
• W4362520779 cites W2147208780 @default.
• W4362520779 cites W2157840751 @default.
• W4362520779 cites W2259802687 @default.
• W4362520779 cites W2316285558 @default.
• W4362520779 cites W2426696734 @default.
• W4362520779 cites W2604153078 @default.
• W4362520779 cites W2611165173 @default.
• W4362520779 cites W2886337344 @default.
• W4362520779 cites W2909149433 @default.
• W4362520779 cites W2922898632 @default.
• W4362520779 cites W3017266548 @default.
• W4362520779 cites W3090719330 @default.
• W4362520779 cites W3127081047 @default.
• W4362520779 cites W3180694348 @default.
• W4362520779 cites W3194086864 @default.
• W4362520779 cites W3212226002 @default.
• W4362520779 cites W4200538472 @default.
• W4362520779 cites W4223535166 @default.
• W4362520779 cites W4285719527 @default.
• W4362520779 cites W4288058655 @default.
• W4362520779 cites W4307583452 @default.
• W4362520779 cites W4320729212 @default.
• W4362520779 doi "https://doi.org/10.1007/s00428-023-03535-4" @default.
• W4362520779 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37012444" @default.
• W4362520779 hasPublicationYear "2023" @default.
• W4362520779 type Work @default.
• W4362520779 citedByCount "0" @default.
• W4362520779 crossrefType "journal-article" @default.
• W4362520779 hasAuthorship W4362520779A5034025853 @default.
• W4362520779 hasAuthorship W4362520779A5051207413 @default.
• W4362520779 hasAuthorship W4362520779A5053906317 @default.
• W4362520779 hasAuthorship W4362520779A5056308350 @default.
• W4362520779 hasAuthorship W4362520779A5068440444 @default.
• W4362520779 hasAuthorship W4362520779A5070525371 @default.
• W4362520779 hasAuthorship W4362520779A5081877908 @default.
• W4362520779 hasBestOaLocation W43625207791 @default.
• W4362520779 hasConcept C102037460 @default.
• W4362520779 hasConcept C104317684 @default.
• W4362520779 hasConcept C121608353 @default.
• W4362520779 hasConcept C126322002 @default.
• W4362520779 hasConcept C142724271 @default.
• W4362520779 hasConcept C143998085 @default.
• W4362520779 hasConcept C193270364 @default.
• W4362520779 hasConcept C204232928 @default.
• W4362520779 hasConcept C2777383545 @default.
• W4362520779 hasConcept C2779012181 @default.
• W4362520779 hasConcept C2780110267 @default.
• W4362520779 hasConcept C502942594 @default.
• W4362520779 hasConcept C530470458 @default.
• W4362520779 hasConcept C55493867 @default.
• W4362520779 hasConcept C71924100 @default.
• W4362520779 hasConcept C84606932 @default.
• W4362520779 hasConcept C86339819 @default.
• W4362520779 hasConcept C86803240 @default.
• W4362520779 hasConcept C98717036 @default.
• W4362520779 hasConceptScore W4362520779C102037460 @default.
• W4362520779 hasConceptScore W4362520779C104317684 @default.
• W4362520779 hasConceptScore W4362520779C121608353 @default.
• W4362520779 hasConceptScore W4362520779C126322002 @default.
• W4362520779 hasConceptScore W4362520779C142724271 @default.
• W4362520779 hasConceptScore W4362520779C143998085 @default.
• W4362520779 hasConceptScore W4362520779C193270364 @default.
• W4362520779 hasConceptScore W4362520779C204232928 @default.
• W4362520779 hasConceptScore W4362520779C2777383545 @default.
• W4362520779 hasConceptScore W4362520779C2779012181 @default.
• W4362520779 hasConceptScore W4362520779C2780110267 @default.
• W4362520779 hasConceptScore W4362520779C502942594 @default.
• W4362520779 hasConceptScore W4362520779C530470458 @default.
• W4362520779 hasConceptScore W4362520779C55493867 @default.
• W4362520779 hasConceptScore W4362520779C71924100 @default.
• W4362520779 hasConceptScore W4362520779C84606932 @default.

• next