FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4362520980> ?p ?o ?g. }

• W4362520980 endingPage "1213" @default.
• W4362520980 startingPage "1197" @default.
• W4362520980 abstract "Abstract Introduction Morphokinetic analysis using a closed time-lapse monitoring system (EmbryoScope + ™) provides quantitative metrics of meiotic progression and cumulus expansion. The goal of this study was to use a physiologic aging mouse model, in which egg aneuploidy levels increase, to determine whether there are age-dependent differences in morphokinetic parameters of oocyte maturation. Methods Denuded oocytes and intact cumulus-oocyte complexes (COCs) were isolated from reproductively young and old mice and in vitro matured in the EmbryoScope + ™. Morphokinetic parameters of meiotic progression and cumulus expansion were evaluated, compared between reproductively young and old mice, and correlated with egg ploidy status. Results Oocytes from reproductively old mice were smaller than young counterparts in terms of GV area (446.42 ± 4.15 vs. 416.79 ± 5.24 µm 2 , p < 0.0001) and oocyte area (4195.71 ± 33.10 vs. 4081.62 ± 41.04 µm 2 , p < 0.05). In addition, the aneuploidy incidence was higher in eggs with advanced reproductive age (24–27% vs. 8–9%, p < 0.05). There were no differences in the morphokinetic parameters of oocyte maturation between oocytes from reproductively young and old mice with respect to time to germinal vesicle breakdown (GVBD) (1.03 ± 0.03 vs. 1.01 ± 0.04 h), polar body extrusion (PBE) (8.56 ± 0.11 vs. 8.52 ± 0.15 h), duration of meiosis I (7.58 ± 0.10 vs. 7.48 ± 0.11 h), and kinetics of cumulus expansion (0.093 ± 0.002 vs. 0.089 ± 0.003 µm/min). All morphokinetic parameters of oocyte maturation were similar between euploid and aneuploid eggs irrespective of age. Conclusion There is no association between age or ploidy and the morphokinetics of mouse oocyte in vitro maturation (IVM). Future studies are needed to evaluate whether there is an association between morphokinetic dynamics of mouse IVM and embryo developmental competence." @default.
• W4362520980 created "2023-04-06" @default.
• W4362520980 creator A5032413676 @default.
• W4362520980 creator A5047358815 @default.
• W4362520980 creator A5065873449 @default.
• W4362520980 creator A5082020231 @default.
• W4362520980 date "2023-04-04" @default.
• W4362520980 modified "2023-10-14" @default.
• W4362520980 title "Morphokinetic parameters of mouse oocyte meiotic maturation and cumulus expansion are not affected by reproductive age or ploidy status" @default.
• W4362520980 cites W1483531844 @default.
• W4362520980 cites W1620825017 @default.
• W4362520980 cites W1845926721 @default.
• W4362520980 cites W1892345804 @default.
• W4362520980 cites W1974916178 @default.
• W4362520980 cites W1976919632 @default.
• W4362520980 cites W1979707418 @default.
• W4362520980 cites W1981768344 @default.
• W4362520980 cites W1992496316 @default.
• W4362520980 cites W1994567108 @default.
• W4362520980 cites W1996857424 @default.
• W4362520980 cites W1999337849 @default.
• W4362520980 cites W2009390858 @default.
• W4362520980 cites W2016276264 @default.
• W4362520980 cites W2019108353 @default.
• W4362520980 cites W2029178312 @default.
• W4362520980 cites W2029394548 @default.
• W4362520980 cites W2044122378 @default.
• W4362520980 cites W2047250802 @default.
• W4362520980 cites W205293060 @default.
• W4362520980 cites W2058732512 @default.
• W4362520980 cites W2061428016 @default.
• W4362520980 cites W2071770630 @default.
• W4362520980 cites W2072703045 @default.
• W4362520980 cites W2072708127 @default.
• W4362520980 cites W2079584602 @default.
• W4362520980 cites W2083057914 @default.
• W4362520980 cites W2084134136 @default.
• W4362520980 cites W2085505753 @default.
• W4362520980 cites W2086358586 @default.
• W4362520980 cites W2088473544 @default.
• W4362520980 cites W2092739399 @default.
• W4362520980 cites W2096528264 @default.
• W4362520980 cites W2096537301 @default.
• W4362520980 cites W2100463657 @default.
• W4362520980 cites W2100512407 @default.
• W4362520980 cites W2110912407 @default.
• W4362520980 cites W2113621013 @default.
• W4362520980 cites W2116761578 @default.
• W4362520980 cites W2124381929 @default.
• W4362520980 cites W2135127763 @default.
• W4362520980 cites W2136935806 @default.
• W4362520980 cites W2137317211 @default.
• W4362520980 cites W2138696931 @default.
• W4362520980 cites W2142206986 @default.
• W4362520980 cites W2145431959 @default.
• W4362520980 cites W2149237119 @default.
• W4362520980 cites W2157077875 @default.
• W4362520980 cites W2166516637 @default.
• W4362520980 cites W2263505154 @default.
• W4362520980 cites W2265023815 @default.
• W4362520980 cites W2289928043 @default.
• W4362520980 cites W2340936863 @default.
• W4362520980 cites W2461066519 @default.
• W4362520980 cites W2497766038 @default.
• W4362520980 cites W2514853184 @default.
• W4362520980 cites W2529392187 @default.
• W4362520980 cites W2534262503 @default.
• W4362520980 cites W2588024230 @default.
• W4362520980 cites W2604130296 @default.
• W4362520980 cites W2724235557 @default.
• W4362520980 cites W2744305255 @default.
• W4362520980 cites W2744366548 @default.
• W4362520980 cites W2756042162 @default.
• W4362520980 cites W2764279830 @default.
• W4362520980 cites W2785691542 @default.
• W4362520980 cites W2789822652 @default.
• W4362520980 cites W2790652587 @default.
• W4362520980 cites W2804653351 @default.
• W4362520980 cites W2872709060 @default.
• W4362520980 cites W2893332042 @default.
• W4362520980 cites W2915005347 @default.
• W4362520980 cites W2936815201 @default.
• W4362520980 cites W2966429881 @default.
• W4362520980 cites W2969755598 @default.
• W4362520980 cites W2980394282 @default.
• W4362520980 cites W3011342905 @default.
• W4362520980 cites W3013695429 @default.
• W4362520980 cites W3024252005 @default.
• W4362520980 cites W3048926192 @default.
• W4362520980 cites W3082805900 @default.
• W4362520980 cites W3114881838 @default.
• W4362520980 cites W3139168703 @default.
• W4362520980 cites W3160943435 @default.
• W4362520980 cites W3172785695 @default.
• W4362520980 cites W3193545945 @default.
• W4362520980 cites W3197162943 @default.
• W4362520980 cites W4206332028 @default.
• W4362520980 cites W4236478801 @default.

• next