Matches in SemOpenAlex for { <https://semopenalex.org/work/W4362531454> ?p ?o ?g. }
Showing items 1 to 97 of
97
with 100 items per page.
- W4362531454 abstract "<p>Supplementary Figure S1: Using reversine to cause chromosome segregation errors and p53-dependent aneuploidy tolerance. Supplementary Figure S2: Validation of APC/C subunits using siRNA deconvolution experiments in RPE1 and HCT116 cells, and how subunit knock-down rescues proliferation when the spindle assembly checkpoint is impaired. Supplementary Figure S3: APC/C subunit knock-down reduces segregation errors caused by SAC defects. Supplementary Figure S4: CRISPR-mediated disruption of TP53 and CDC27, and resistance to Mps1 inhibitors. Supplementary Figure S5: Functional testing of CDC27 mutations in Schizosaccharomyces pombe. Supplementary Figure S6: Cell division, microtubule attachment errors and tetraploidy. Supplementary Figure S7: CRISPR-mediated disruption of TP53 in RPE1 cells. Supplementary Figure S8: APC/C partial inhibition does not rescue structural anaphase defects caused by pre-mitotic replicative stress. Supplementary Figure S9: Spindle microtubule stability using photoactivation. Supplementary Figure S10: Adaptation of RPE1/p53ko populations to Mps1 inhibitors is accompanied by a mitotic delay.</p>" @default.
- W4362531454 created "2023-04-06" @default.
- W4362531454 creator A5000879181 @default.
- W4362531454 creator A5016475369 @default.
- W4362531454 creator A5017175813 @default.
- W4362531454 creator A5019124036 @default.
- W4362531454 creator A5022369551 @default.
- W4362531454 creator A5025488519 @default.
- W4362531454 creator A5041131742 @default.
- W4362531454 creator A5048027649 @default.
- W4362531454 creator A5051520092 @default.
- W4362531454 creator A5054337695 @default.
- W4362531454 creator A5055945260 @default.
- W4362531454 creator A5056141826 @default.
- W4362531454 creator A5056525592 @default.
- W4362531454 creator A5056893617 @default.
- W4362531454 creator A5057095262 @default.
- W4362531454 creator A5074565662 @default.
- W4362531454 creator A5080913663 @default.
- W4362531454 creator A5090314471 @default.
- W4362531454 date "2023-04-03" @default.
- W4362531454 modified "2023-10-03" @default.
- W4362531454 title "Supplementary Figures S1 - S10 from APC/C Dysfunction Limits Excessive Cancer Chromosomal Instability" @default.
- W4362531454 doi "https://doi.org/10.1158/2159-8290.22531362" @default.
- W4362531454 hasPublicationYear "2023" @default.
- W4362531454 type Work @default.
- W4362531454 citedByCount "0" @default.
- W4362531454 crossrefType "posted-content" @default.
- W4362531454 hasAuthorship W4362531454A5000879181 @default.
- W4362531454 hasAuthorship W4362531454A5016475369 @default.
- W4362531454 hasAuthorship W4362531454A5017175813 @default.
- W4362531454 hasAuthorship W4362531454A5019124036 @default.
- W4362531454 hasAuthorship W4362531454A5022369551 @default.
- W4362531454 hasAuthorship W4362531454A5025488519 @default.
- W4362531454 hasAuthorship W4362531454A5041131742 @default.
- W4362531454 hasAuthorship W4362531454A5048027649 @default.
- W4362531454 hasAuthorship W4362531454A5051520092 @default.
- W4362531454 hasAuthorship W4362531454A5054337695 @default.
- W4362531454 hasAuthorship W4362531454A5055945260 @default.
- W4362531454 hasAuthorship W4362531454A5056141826 @default.
- W4362531454 hasAuthorship W4362531454A5056525592 @default.
- W4362531454 hasAuthorship W4362531454A5056893617 @default.
- W4362531454 hasAuthorship W4362531454A5057095262 @default.
- W4362531454 hasAuthorship W4362531454A5074565662 @default.
- W4362531454 hasAuthorship W4362531454A5080913663 @default.
- W4362531454 hasAuthorship W4362531454A5090314471 @default.
- W4362531454 hasBestOaLocation W43625314541 @default.
- W4362531454 hasConcept C104317684 @default.
- W4362531454 hasConcept C107888121 @default.
- W4362531454 hasConcept C121608353 @default.
- W4362531454 hasConcept C140752955 @default.
- W4362531454 hasConcept C175732170 @default.
- W4362531454 hasConcept C192838845 @default.
- W4362531454 hasConcept C2778354886 @default.
- W4362531454 hasConcept C29537977 @default.
- W4362531454 hasConcept C30481170 @default.
- W4362531454 hasConcept C502942594 @default.
- W4362531454 hasConcept C53420372 @default.
- W4362531454 hasConcept C54355233 @default.
- W4362531454 hasConcept C86803240 @default.
- W4362531454 hasConcept C93304396 @default.
- W4362531454 hasConcept C95444343 @default.
- W4362531454 hasConcept C98108389 @default.
- W4362531454 hasConceptScore W4362531454C104317684 @default.
- W4362531454 hasConceptScore W4362531454C107888121 @default.
- W4362531454 hasConceptScore W4362531454C121608353 @default.
- W4362531454 hasConceptScore W4362531454C140752955 @default.
- W4362531454 hasConceptScore W4362531454C175732170 @default.
- W4362531454 hasConceptScore W4362531454C192838845 @default.
- W4362531454 hasConceptScore W4362531454C2778354886 @default.
- W4362531454 hasConceptScore W4362531454C29537977 @default.
- W4362531454 hasConceptScore W4362531454C30481170 @default.
- W4362531454 hasConceptScore W4362531454C502942594 @default.
- W4362531454 hasConceptScore W4362531454C53420372 @default.
- W4362531454 hasConceptScore W4362531454C54355233 @default.
- W4362531454 hasConceptScore W4362531454C86803240 @default.
- W4362531454 hasConceptScore W4362531454C93304396 @default.
- W4362531454 hasConceptScore W4362531454C95444343 @default.
- W4362531454 hasConceptScore W4362531454C98108389 @default.
- W4362531454 hasLocation W43625314541 @default.
- W4362531454 hasLocation W43625314542 @default.
- W4362531454 hasLocation W43625314543 @default.
- W4362531454 hasOpenAccess W4362531454 @default.
- W4362531454 hasPrimaryLocation W43625314541 @default.
- W4362531454 hasRelatedWork W1997671833 @default.
- W4362531454 hasRelatedWork W2008174897 @default.
- W4362531454 hasRelatedWork W2024065607 @default.
- W4362531454 hasRelatedWork W2089806746 @default.
- W4362531454 hasRelatedWork W2129153399 @default.
- W4362531454 hasRelatedWork W2509374032 @default.
- W4362531454 hasRelatedWork W2605117767 @default.
- W4362531454 hasRelatedWork W2802052189 @default.
- W4362531454 hasRelatedWork W3014101944 @default.
- W4362531454 hasRelatedWork W4280548883 @default.
- W4362531454 isParatext "false" @default.
- W4362531454 isRetracted "false" @default.
- W4362531454 workType "article" @default.