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W4362534720 abstract "<p>Supplementary Figure S1. Retention of MEDI3726 activity in human, cynomolgus monkey plasma or PBS for up to 7 days. Supplementary Figure S2. Kaplan-Meier analysis of the Time-to-Endpoint Survival in the (A) LNCaP, (B) CWR22Rv1, and (C) PC-3 Xenograft Studies. Supplementary Figure S3. In Vivo Activity of Isotype Control in CWR22Rv1 the Xenograft Model. Supplementary Figure S4. Cytotoxicity of the Warheads and Their Associated ADCs. Supplementary Figure S5. gamma-H2AX IHC Results. Supplementary Figure S6. Body weight measurements from a representative cell line xenograft and a LuCaP PDX in vivo activity studies. Supplementary Figure S7. Hematology Parameters (Males) following MEDI3726 Administration at 0 (control) & 0.6 mg/kg.</p>" @default.
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W4362534720 date "2023-04-03" @default.
W4362534720 modified "2023-10-18" @default.
W4362534720 title "Supplementary Figures S1-S7 from Antitumor Activity of MEDI3726 (ADCT-401), a Pyrrolobenzodiazepine Antibody–Drug Conjugate Targeting PSMA, in Preclinical Models of Prostate Cancer" @default.
W4362534720 doi "https://doi.org/10.1158/1535-7163.22505436.v1" @default.
W4362534720 hasPublicationYear "2023" @default.
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