FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4362566630> ?p ?o ?g. }

• W4362566630 abstract "Introduction A negative association between C-terminal fibroblast growth factor 23 (cFGF23) and hemoglobin (Hb) levels has been reported in patients with predialysis chronic kidney disease. In dialysis patients, the dominant form of serum FGF23 is intact FGF23 (iFGF23); however, its association with the Hb level remains unclear. Therefore, simultaneously monitoring iFGF23 and cFGF23 levels is crucial. In this study, we investigated the associations between both forms of FGF23 (iFGF23 and cFGF23) and renal anemia in chronic hemodialysis (CHD) patients. Methods We included 166 CHD patients from two hospitals in this cross-sectional, observational study. The primary predictors were serum iFGF23, cFGF23, and iFGF23/cFGF23 levels. The main outcome was the Hb level. Results Among the CHD patients included, 60.8% were men with a mean age of 59.4 ± 12.7 years. In the crude analysis, iFGF23 and iFGF23/cFGF23 levels showed a significant negative association (−0.27, p = 0.004 and −0.22, p = 0.034, respectively) with the Hb level. Even after adjusting for multiple variables (a parsimonious model), every increment of natural log transformation by 1 for (ln)iFGF23 and ln(iFGF23/cFGF23) levels showed a negative correlation with the Hb level (estimate: −0.27 [95%CI: −0.44, −0.10, p = 0.001]; −0.19 [95%CI: −0.37, −0.01, p = 0.042], respectively), whereas both were positively associated with erythropoietin-stimulating agent (ESA) hyporesponsiveness (odds ratio [OR]: [95%CI: 2.30, 1.26–4.17], p = 0.006; 1.95 [95%CI: 1.08–3.50], p = 0.025). Moreover, these abovementioned associations were more dominant in patients with diabetes who used angiotensin receptor blockers. Discussion In conclusion, a negative association between serum iFGF23 or iFGF23/cFGF23 level and the Hb level was observed in our CHD patients. Meanwhile, a higher iFGF23 or iFGF23/cFGF23 level may predispose patients to ESA hyporesponsiveness." @default.
• W4362566630 created "2023-04-06" @default.
• W4362566630 creator A5006890879 @default.
• W4362566630 creator A5034740849 @default.
• W4362566630 creator A5039193616 @default.
• W4362566630 creator A5048561204 @default.
• W4362566630 creator A5051883753 @default.
• W4362566630 creator A5065534512 @default.
• W4362566630 creator A5083075778 @default.
• W4362566630 date "2023-04-04" @default.
• W4362566630 modified "2023-10-01" @default.
• W4362566630 title "High intact fibroblast growth factor 23 levels associated with low hemoglobin levels in patients on chronic hemodialysis" @default.
• W4362566630 cites W1549105976 @default.
• W4362566630 cites W1861102083 @default.
• W4362566630 cites W1963306946 @default.
• W4362566630 cites W1982203537 @default.
• W4362566630 cites W1984393349 @default.
• W4362566630 cites W1986126285 @default.
• W4362566630 cites W1987601001 @default.
• W4362566630 cites W1988799854 @default.
• W4362566630 cites W1998100845 @default.
• W4362566630 cites W2080296001 @default.
• W4362566630 cites W2082263332 @default.
• W4362566630 cites W2082913510 @default.
• W4362566630 cites W2086545695 @default.
• W4362566630 cites W2093187956 @default.
• W4362566630 cites W2094551185 @default.
• W4362566630 cites W2135672809 @default.
• W4362566630 cites W2137591192 @default.
• W4362566630 cites W2146045604 @default.
• W4362566630 cites W2159397492 @default.
• W4362566630 cites W2333562199 @default.
• W4362566630 cites W2339834305 @default.
• W4362566630 cites W2398921501 @default.
• W4362566630 cites W2426424112 @default.
• W4362566630 cites W2559952413 @default.
• W4362566630 cites W2572770153 @default.
• W4362566630 cites W2611425307 @default.
• W4362566630 cites W2618728844 @default.
• W4362566630 cites W2744568453 @default.
• W4362566630 cites W2769367888 @default.
• W4362566630 cites W2783722462 @default.
• W4362566630 cites W2789330893 @default.
• W4362566630 cites W2799444074 @default.
• W4362566630 cites W2802485351 @default.
• W4362566630 cites W2805258093 @default.
• W4362566630 cites W2806860260 @default.
• W4362566630 cites W2896713857 @default.
• W4362566630 cites W2970368210 @default.
• W4362566630 cites W2970992039 @default.
• W4362566630 cites W2991164353 @default.
• W4362566630 cites W3012262428 @default.
• W4362566630 cites W3047335527 @default.
• W4362566630 cites W3048819657 @default.
• W4362566630 cites W3147940220 @default.
• W4362566630 cites W3148139037 @default.
• W4362566630 doi "https://doi.org/10.3389/fmed.2023.1098871" @default.
• W4362566630 hasPublicationYear "2023" @default.
• W4362566630 type Work @default.
• W4362566630 citedByCount "0" @default.
• W4362566630 crossrefType "journal-article" @default.
• W4362566630 hasAuthorship W4362566630A5006890879 @default.
• W4362566630 hasAuthorship W4362566630A5034740849 @default.
• W4362566630 hasAuthorship W4362566630A5039193616 @default.
• W4362566630 hasAuthorship W4362566630A5048561204 @default.
• W4362566630 hasAuthorship W4362566630A5051883753 @default.
• W4362566630 hasAuthorship W4362566630A5065534512 @default.
• W4362566630 hasAuthorship W4362566630A5083075778 @default.
• W4362566630 hasBestOaLocation W43625666301 @default.
• W4362566630 hasConcept C114276007 @default.
• W4362566630 hasConcept C126322002 @default.
• W4362566630 hasConcept C134018914 @default.
• W4362566630 hasConcept C156957248 @default.
• W4362566630 hasConcept C2778063415 @default.
• W4362566630 hasConcept C2778248108 @default.
• W4362566630 hasConcept C2778319317 @default.
• W4362566630 hasConcept C2778653478 @default.
• W4362566630 hasConcept C2778917026 @default.
• W4362566630 hasConcept C2779978075 @default.
• W4362566630 hasConcept C2781208988 @default.
• W4362566630 hasConcept C519063684 @default.
• W4362566630 hasConcept C71924100 @default.
• W4362566630 hasConcept C90924648 @default.
• W4362566630 hasConceptScore W4362566630C114276007 @default.
• W4362566630 hasConceptScore W4362566630C126322002 @default.
• W4362566630 hasConceptScore W4362566630C134018914 @default.
• W4362566630 hasConceptScore W4362566630C156957248 @default.
• W4362566630 hasConceptScore W4362566630C2778063415 @default.
• W4362566630 hasConceptScore W4362566630C2778248108 @default.
• W4362566630 hasConceptScore W4362566630C2778319317 @default.
• W4362566630 hasConceptScore W4362566630C2778653478 @default.
• W4362566630 hasConceptScore W4362566630C2778917026 @default.
• W4362566630 hasConceptScore W4362566630C2779978075 @default.
• W4362566630 hasConceptScore W4362566630C2781208988 @default.
• W4362566630 hasConceptScore W4362566630C519063684 @default.
• W4362566630 hasConceptScore W4362566630C71924100 @default.
• W4362566630 hasConceptScore W4362566630C90924648 @default.
• W4362566630 hasFunder F4320322544 @default.
• W4362566630 hasFunder F4320331164 @default.
• W4362566630 hasLocation W43625666301 @default.

• next