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- W4362568638 abstract "Abstract Hydrogels, as 3D networks containing huge amount of water, display similarity to soft tissues, and thus they are of wide interest in tissue engineering. Hydrogels, due to biocompatibility and porous structure, are valuable therapeutic platforms for hydrophilic drugs. Over the last decade, there has been a strong emphasis on the development of hydrogel platforms with the ability to increase the solubility of hydrophobic drugs. However, the pronounced discrepancy between the hydrophilic character of hydrogels and the hydrophobic nature of numerous pharmacologically active compounds is problematic. In recent years, different strategies are applied using special polymer constructs or composite materials exploiting the advanced scientific knowledge in the area of polymer and lipid‐based nano‐ and microcarriers hydrophobization of the hydrogel turns out to be not only valuable in terms of achieving the ability to dissolve poorly soluble drugs in water, but also proves to be crucial in obtaining bioadhesion in wet conditions, but also, unexpected abnormal water swelling behavior, as well as in mechanical properties such as the dissipation mechanism and self‐healable hydrogel properties. This review is mainly focused on recent advances in the usage of hydrophobized hydrogels in biomedical applications." @default.
- W4362568638 created "2023-04-06" @default.
- W4362568638 creator A5059631305 @default.
- W4362568638 creator A5067575784 @default.
- W4362568638 creator A5085743762 @default.
- W4362568638 date "2023-04-03" @default.
- W4362568638 modified "2023-09-27" @default.
- W4362568638 title "Hydrophobized Hydrogels: Construction Strategies, Properties, and Biomedical Applications" @default.
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