FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4362585812> ?p ?o ?g. }

• W4362585812 endingPage "739544" @default.
• W4362585812 startingPage "739544" @default.
• W4362585812 abstract "Vibrio parahaemolyticus, an important aquatic pathogen, is the causative agent of numerous high mortality disease outbreaks in shrimp industry. Recent studies have found that V. parahaemolyticus outer membrane proteins (OMPs) may homology with shrimp plasma proteins, and could potentially regulate the immune responses of shrimps against pathogens. In this study, we identified that the outer membrane protein LamB of V. parahaemolyticus reacted with anti-hemocyanin antibody using affinity proteomics approach, Western blot and Dot-ELISA analysis. CTL epitope predictions identified 11 homologous epitopes between LamB and Litopenaeus vannamei hemocyanin. In addition, seven potential LamB interaction proteins, including β-1,3-glucan-binding protein (LGBP), β-actin, Toll2, actin T2, enolase partial, arginine kinase and hemocyanin, were identified from shrimp plasma by co-immunoprecipitation (Co-IP) and LC-ESI-MS/MS. In particular, we found that rLamB could could bind HMC, rLGBP and rToll2, and down-regulate the expression level of Toll2, LGBP and hemocyanin upon pathogen infection. Moreover, rLamB increased the bacterial loading in shrimp hemolymph at 12 h and 24 h. Taken together, these findings reveal the important role of LamB in recognition and negative regulation of the host's immune system upon bacterial infection." @default.
• W4362585812 created "2023-04-06" @default.
• W4362585812 creator A5005761705 @default.
• W4362585812 creator A5021089196 @default.
• W4362585812 creator A5021555799 @default.
• W4362585812 creator A5051774157 @default.
• W4362585812 creator A5071278984 @default.
• W4362585812 creator A5086946220 @default.
• W4362585812 date "2023-07-01" @default.
• W4362585812 modified "2023-09-25" @default.
• W4362585812 title "LamB as a potential negative regulator to the immune response of shrimp Litopenaeus vannamei upon Vibrio parahaemolyticus infection" @default.
• W4362585812 cites W1501119534 @default.
• W4362585812 cites W1967618296 @default.
• W4362585812 cites W1991260010 @default.
• W4362585812 cites W2020606069 @default.
• W4362585812 cites W2027116213 @default.
• W4362585812 cites W2038264912 @default.
• W4362585812 cites W2044774423 @default.
• W4362585812 cites W2048699880 @default.
• W4362585812 cites W2059408709 @default.
• W4362585812 cites W2062232329 @default.
• W4362585812 cites W2072842607 @default.
• W4362585812 cites W2124371255 @default.
• W4362585812 cites W2156618766 @default.
• W4362585812 cites W2418694942 @default.
• W4362585812 cites W2498751511 @default.
• W4362585812 cites W2513596760 @default.
• W4362585812 cites W2535630741 @default.
• W4362585812 cites W2592002918 @default.
• W4362585812 cites W2597778685 @default.
• W4362585812 cites W2625108725 @default.
• W4362585812 cites W2794106344 @default.
• W4362585812 cites W2896014506 @default.
• W4362585812 cites W2900798772 @default.
• W4362585812 cites W2912724961 @default.
• W4362585812 cites W2938897877 @default.
• W4362585812 cites W2961876873 @default.
• W4362585812 cites W2967099009 @default.
• W4362585812 cites W3036026016 @default.
• W4362585812 cites W3038588865 @default.
• W4362585812 cites W3083856063 @default.
• W4362585812 cites W3118786354 @default.
• W4362585812 cites W3194060476 @default.
• W4362585812 cites W4200468206 @default.
• W4362585812 cites W4224316706 @default.
• W4362585812 doi "https://doi.org/10.1016/j.aquaculture.2023.739544" @default.
• W4362585812 hasPublicationYear "2023" @default.
• W4362585812 type Work @default.
• W4362585812 citedByCount "0" @default.
• W4362585812 crossrefType "journal-article" @default.
• W4362585812 hasAuthorship W4362585812A5005761705 @default.
• W4362585812 hasAuthorship W4362585812A5021089196 @default.
• W4362585812 hasAuthorship W4362585812A5021555799 @default.
• W4362585812 hasAuthorship W4362585812A5051774157 @default.
• W4362585812 hasAuthorship W4362585812A5071278984 @default.
• W4362585812 hasAuthorship W4362585812A5086946220 @default.
• W4362585812 hasConcept C100068826 @default.
• W4362585812 hasConcept C104317684 @default.
• W4362585812 hasConcept C136449434 @default.
• W4362585812 hasConcept C159047783 @default.
• W4362585812 hasConcept C159654299 @default.
• W4362585812 hasConcept C18903297 @default.
• W4362585812 hasConcept C195616568 @default.
• W4362585812 hasConcept C203014093 @default.
• W4362585812 hasConcept C2776154503 @default.
• W4362585812 hasConcept C2776415932 @default.
• W4362585812 hasConcept C2776575720 @default.
• W4362585812 hasConcept C2776841996 @default.
• W4362585812 hasConcept C2777013287 @default.
• W4362585812 hasConcept C2778968793 @default.
• W4362585812 hasConcept C2779771762 @default.
• W4362585812 hasConcept C2779915011 @default.
• W4362585812 hasConcept C523546767 @default.
• W4362585812 hasConcept C54355233 @default.
• W4362585812 hasConcept C55493867 @default.
• W4362585812 hasConcept C86803240 @default.
• W4362585812 hasConcept C8891405 @default.
• W4362585812 hasConcept C89423630 @default.
• W4362585812 hasConceptScore W4362585812C100068826 @default.
• W4362585812 hasConceptScore W4362585812C104317684 @default.
• W4362585812 hasConceptScore W4362585812C136449434 @default.
• W4362585812 hasConceptScore W4362585812C159047783 @default.
• W4362585812 hasConceptScore W4362585812C159654299 @default.
• W4362585812 hasConceptScore W4362585812C18903297 @default.
• W4362585812 hasConceptScore W4362585812C195616568 @default.
• W4362585812 hasConceptScore W4362585812C203014093 @default.
• W4362585812 hasConceptScore W4362585812C2776154503 @default.
• W4362585812 hasConceptScore W4362585812C2776415932 @default.
• W4362585812 hasConceptScore W4362585812C2776575720 @default.
• W4362585812 hasConceptScore W4362585812C2776841996 @default.
• W4362585812 hasConceptScore W4362585812C2777013287 @default.
• W4362585812 hasConceptScore W4362585812C2778968793 @default.
• W4362585812 hasConceptScore W4362585812C2779771762 @default.
• W4362585812 hasConceptScore W4362585812C2779915011 @default.
• W4362585812 hasConceptScore W4362585812C523546767 @default.
• W4362585812 hasConceptScore W4362585812C54355233 @default.
• W4362585812 hasConceptScore W4362585812C55493867 @default.
• W4362585812 hasConceptScore W4362585812C86803240 @default.

• next