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• W4362586989 abstract "PurposeLeadless pacemakers may have a lower risk of cardiac device infection and/or bacteremia, compared with the transvenous system. Patients with cardiac transplant are at increased risk of cardiovascular implantable electronic device complications, but there is limited data on the safety and effectiveness of leadless pacemakers in these patients.MethodsRetrospective chart review of all heart transplant recipients followed at Mount Sinai Hospital between April 1st 2018 and October 1st, 2022 identified 12 patients who received a leadless pacemaker, 4 patients who received transvenous pacemaker and 1 patient who received an epicardial pacemaker. Data on demographics, clinical characteristics, pacemaker interrogations, device changes, endomyocardial biopsies, and cardiac allograft vasculopathy screening were collected.ResultsPlacement of leadless pacemaker was feasible in all 12 patients. Two patients changed to a transvenous system due to ventricular dyssynchrony. No patients developed a bradyarrhythmia during follow up. Twelve endomyocardial biopsies were performed without complication and all were negative for rejection (Table 1). In the 5 patients who received pacemakers by more traditional approaches, one developed a lead infection.ConclusionLeadless pacemaker implantation appears to be a feasible option post heart transplant without device infections but with occasional need to upgrade to transvenous pacing systems device changes due to ventricular dyssynchrony. Further research is required to assess the efficacy and safety of leadless pacemakers in patients with history of heart transplant. Leadless pacemakers may have a lower risk of cardiac device infection and/or bacteremia, compared with the transvenous system. Patients with cardiac transplant are at increased risk of cardiovascular implantable electronic device complications, but there is limited data on the safety and effectiveness of leadless pacemakers in these patients. Retrospective chart review of all heart transplant recipients followed at Mount Sinai Hospital between April 1st 2018 and October 1st, 2022 identified 12 patients who received a leadless pacemaker, 4 patients who received transvenous pacemaker and 1 patient who received an epicardial pacemaker. Data on demographics, clinical characteristics, pacemaker interrogations, device changes, endomyocardial biopsies, and cardiac allograft vasculopathy screening were collected. Placement of leadless pacemaker was feasible in all 12 patients. Two patients changed to a transvenous system due to ventricular dyssynchrony. No patients developed a bradyarrhythmia during follow up. Twelve endomyocardial biopsies were performed without complication and all were negative for rejection (Table 1). In the 5 patients who received pacemakers by more traditional approaches, one developed a lead infection. Leadless pacemaker implantation appears to be a feasible option post heart transplant without device infections but with occasional need to upgrade to transvenous pacing systems device changes due to ventricular dyssynchrony. Further research is required to assess the efficacy and safety of leadless pacemakers in patients with history of heart transplant." @default.
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• W4362586989 date "2023-04-01" @default.
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• W4362586989 title "(487) Use of Leadless Cardiac Pacemakers in Heart Transplant Recipients: A Case Series" @default.
• W4362586989 doi "https://doi.org/10.1016/j.healun.2023.02.502" @default.
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