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- W4362610123 abstract "<p>Supplementary Figure 1 | IGF1R inhibition by NVP-AEW541 increases sensitivity to PI3K inhibition by GDC-0941 in HCC1806 and CAL-51 cells Supplementary Figure 2 | GDC-0941 dose-response curves of the TNBC cell line panel at different concentrations of OSI-906 Supplementary Figure 3 | IGF1R, pIGF1R and IGF2BP3 levels in the 18 cell lines of the panel Supplementary Figure 4 | Sensitivity of the TNBC cell line panel to MEK-inhibitor PD-0325901 Supplementary Figure 5 | Dynamic quantification of apoptosis in CAL-51 cells after drug exposure Supplementary Figure 6 | HCC1806 cells become resistant to GDC-0941 after prolonged exposure but are still sensitive to combination treatment Supplementary Figure 7 | Overexpression of IGF1R has no significant effect on sensitivity to GDC-0941 in HCC1806, CAL-51, CAL-148 and MFM-223 cells Supplementary Figure 8 | Colony outgrowth of wild type and IGF1R-overexpressing cell lines Supplementary Figure 9 | Antibodies raised against IGF2 do not modulate the response of CAL-148 and MFM-223 cells to GDC-0941</p>" @default.
- W4362610123 created "2023-04-06" @default.
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- W4362610123 date "2023-04-03" @default.
- W4362610123 modified "2023-09-29" @default.
- W4362610123 title "Supplemental Figures 1 to 9 from Sensitizing Triple-Negative Breast Cancer to PI3K Inhibition by Cotargeting IGF1R" @default.
- W4362610123 doi "https://doi.org/10.1158/1535-7163.22508080" @default.
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