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- W4362633102 abstract "•Our understanding is incomplete for high-altitude (HA) adaption. •A population neuro-geno-type gap exist due to HA immigrants. •HA-related neurotypes are proposed to decipher their genetic roles. •Population neuroscience provides a blueprint for future HA studies. •A Tibetans cohort will be the first step of imaging HA populations. Brain Structural and Functional Alterations in Native Tibetans Living at High AltitudeNeuroscienceVol. 520PreviewThe native Tibetan population has lived at high altitude for more than 30000 years (Meyer et al., 2017), and show unique physiological characteristics which have allowed adaptations to hypoxic environments, including reduced arterial oxygen content, increased resting ventilation, lack of hypoxic pulmonary vasoconstriction, reduced incidence of low birth weight, and relatively low hemoglobin concentration (Simonson et al., 2010; Xin et al., 2020). Physiological adaptations to the high altitude environments, such as the cardiovascular and respiratory systems, may act on their corresponding control centers in the brain via afferent feedback (Hoiland et al., 2018). Full-Text PDF" @default.
- W4362633102 created "2023-04-07" @default.
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- W4362633102 date "2023-06-01" @default.
- W4362633102 modified "2023-09-27" @default.
- W4362633102 title "Uncoiling the Scroll of High-altitude Population Imaging: Native Brains in Tibet" @default.
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- W4362633102 doi "https://doi.org/10.1016/j.neuroscience.2023.03.026" @default.
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