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- W4362635695 abstract "<p>PDF - 352K, Supplemental Figure 1: Chemical structures of the molecules used in the studies. Supplemental Figure 2: Effects of (R)-JQ1 in AML cells. Supplemental Figure 3: ChIP of BRD4 and POLII in JQ1 treated AML cells. Supplemental Figure 4: JQ1 effects on CDK6 mRNA expression in AML cells. Supplemental Figure 5: JQ1 effects on mRNA and protein expression in FLT3-ITD expressing AML cells. Supplemental Figure 6: Isobologram analyses of BET protein antagonist and PS in AML cells. Supplemental Table 1: Clinical presentation and mutation status of primary AML samples. Supplemental Table 2: Top gene expression changes in AML cells following JQ1 treatment. Supplemental Table 3: Ingenuity Pathway analysis of AML cells following JQ1 treatment.</p>" @default.
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- W4362635695 date "2023-04-03" @default.
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- W4362635695 title "Supplementary Figures 1 through 6 and Supplementary Tables 1 through 3 from Highly Active Combination of BRD4 Antagonist and Histone Deacetylase Inhibitor against Human Acute Myelogenous Leukemia Cells" @default.
- W4362635695 doi "https://doi.org/10.1158/1535-7163.22501209.v1" @default.
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