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- W4362657024 endingPage "1785" @default.
- W4362657024 startingPage "1775" @default.
- W4362657024 abstract "Abstract Cadmium (Cd) is an environmental heavy metal, and its accumulation is harmful to animal and human health. The cytotoxicity of Cd includes oxidative stress, apoptosis, and mitochondrial histopathological changes. Furthermore, polystyrene (PS) is a kind of microplastic piece derived from biotic and abiotic weathering courses, and has toxicity in various aspects. However, the potential mechanism of action of Cd co‐treated with PS is still poorly unclear. The objective of this study was to investigate the effects of PS on Cd‐induced histopathological injury of mitochondria in the lung of mice. In this study, the results have showed that Cd could induce the activity of oxidative enzymes of the lung cells in mice, increasing the content of partial microelement and the phosphorylation of inflammatory factor NF‐κB p65. Cd further destroys the integrity of mitochondria by increasing the expression of apoptotic protein and blocking the autophagy. In addition, PS solely group aggravated the lung damage in mice, especially mitochondrial toxicity, and played a synergistic effect with Cd in lung injury. However, how PS can augment mitochondrial damage and synergism with Cd in lung of mice requiring further exploration. Therefore, PS was able to exacerbate Cd‐induced mitochondrial damage to the lung in mice by blocking autophagy, and was associated with the apoptosis." @default.
- W4362657024 created "2023-04-07" @default.
- W4362657024 creator A5005836955 @default.
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- W4362657024 creator A5060183623 @default.
- W4362657024 creator A5069820887 @default.
- W4362657024 creator A5083991931 @default.
- W4362657024 date "2023-04-06" @default.
- W4362657024 modified "2023-10-14" @default.
- W4362657024 title "Polystyrene exacerbates cadmium‐induced mitochondrial damage to lung by blocking autophagy in mice" @default.
- W4362657024 cites W1756237694 @default.
- W4362657024 cites W1975360923 @default.
- W4362657024 cites W1983947492 @default.
- W4362657024 cites W1985730402 @default.
- W4362657024 cites W1990919981 @default.
- W4362657024 cites W2010201651 @default.
- W4362657024 cites W2011735999 @default.
- W4362657024 cites W2041736359 @default.
- W4362657024 cites W2065059030 @default.
- W4362657024 cites W2065548391 @default.
- W4362657024 cites W2069023359 @default.
- W4362657024 cites W2073588035 @default.
- W4362657024 cites W2078004915 @default.
- W4362657024 cites W2084757815 @default.
- W4362657024 cites W2086215413 @default.
- W4362657024 cites W2087875625 @default.
- W4362657024 cites W2091551634 @default.
- W4362657024 cites W2110845635 @default.
- W4362657024 cites W2129308384 @default.
- W4362657024 cites W2132357771 @default.
- W4362657024 cites W2155015733 @default.
- W4362657024 cites W2169904088 @default.
- W4362657024 cites W2194780841 @default.
- W4362657024 cites W235258576 @default.
- W4362657024 cites W2402444290 @default.
- W4362657024 cites W2507355327 @default.
- W4362657024 cites W2507586450 @default.
- W4362657024 cites W2561943186 @default.
- W4362657024 cites W2608368045 @default.
- W4362657024 cites W2756985996 @default.
- W4362657024 cites W2763113116 @default.
- W4362657024 cites W2789500366 @default.
- W4362657024 cites W2791564057 @default.
- W4362657024 cites W2885411864 @default.
- W4362657024 cites W2888126954 @default.
- W4362657024 cites W2889479406 @default.
- W4362657024 cites W2889742898 @default.
- W4362657024 cites W2892885037 @default.
- W4362657024 cites W2895385641 @default.
- W4362657024 cites W2902416164 @default.
- W4362657024 cites W2903885365 @default.
- W4362657024 cites W2914425661 @default.
- W4362657024 cites W2947932741 @default.
- W4362657024 cites W2954207903 @default.
- W4362657024 cites W2965413929 @default.
- W4362657024 cites W2980622391 @default.
- W4362657024 cites W2984919965 @default.
- W4362657024 cites W2987473186 @default.
- W4362657024 cites W2989218594 @default.
- W4362657024 cites W2990221627 @default.
- W4362657024 cites W2992348664 @default.
- W4362657024 cites W2999331175 @default.
- W4362657024 cites W3007155206 @default.
- W4362657024 cites W3007684422 @default.
- W4362657024 cites W3016965350 @default.
- W4362657024 cites W3024286687 @default.
- W4362657024 cites W3032103849 @default.
- W4362657024 cites W3036300605 @default.
- W4362657024 cites W3039536655 @default.
- W4362657024 cites W3099939759 @default.
- W4362657024 cites W3140630531 @default.
- W4362657024 cites W3142044721 @default.
- W4362657024 cites W3146378258 @default.
- W4362657024 cites W3179374736 @default.
- W4362657024 cites W3194875302 @default.
- W4362657024 cites W3197826302 @default.
- W4362657024 cites W3199995631 @default.
- W4362657024 cites W3202744779 @default.
- W4362657024 cites W3213695592 @default.
- W4362657024 cites W3214169657 @default.
- W4362657024 cites W3215982602 @default.
- W4362657024 cites W4200045464 @default.
- W4362657024 cites W4210483538 @default.
- W4362657024 cites W4210528896 @default.
- W4362657024 cites W4221099709 @default.
- W4362657024 cites W4223902686 @default.
- W4362657024 cites W4224943620 @default.
- W4362657024 cites W4229054382 @default.
- W4362657024 cites W4248078302 @default.
- W4362657024 cites W4281383987 @default.
- W4362657024 cites W4281761028 @default.
- W4362657024 cites W4282015560 @default.