Matches in SemOpenAlex for { <https://semopenalex.org/work/W4362657936> ?p ?o ?g. }
- W4362657936 endingPage "e0283873" @default.
- W4362657936 startingPage "e0283873" @default.
- W4362657936 abstract "Respiratory syncytial virus (RSV) is the leading cause of lower respiratory tract infections and hospitalization in infants and young children. Here, we analyzed the genetic diversity of RSV using partial G gene sequences in 84 RSV-A and 78 RSV- B positive samples collected in Seoul, South Korea, for 10 consecutive years, from 2010 to 2019. Our phylogenetic analysis revealed that RSV-A strains were classified into either the ON1 (80.9%) or NA1 (19.0%) genotypes. On the other hand, RSV-B strains demonstrated diversified clusters within the BA genotype. Notably, some sequences designated as BA-SE, BA-SE1, and BA-DIS did not cluster with previously identified BA genotypes in the phylogenetic trees. Despite this, they did not meet the criteria for the assignment of a new genotype based on recent classification methods. Selection pressure analysis identified three positive selection sites (amino acid positions 273, 274, and 298) in RSV-A, and one possible positive selection site (amino acid position 296) in RSV-B, respectively. The mean evolutionary rates of Korean RSV-A from 1999 to 2019 and RSV-B strains from 1991 and 2019 were estimated at 3.51 × 10-3 nucleotides (nt) substitutions/site/year and 3.32 × 10-3 nt substitutions/site/year, respectively. The population dynamics in the Bayesian skyline plot revealed fluctuations corresponding to the emergence of dominant strains, including a switch of the dominant genotype from NA1 to ON1. Our study on time-scaled cumulative evolutionary analysis contributes to a better understanding of RSV epidemiology at the local level in South Korea." @default.
- W4362657936 created "2023-04-07" @default.
- W4362657936 creator A5011178337 @default.
- W4362657936 creator A5018386699 @default.
- W4362657936 creator A5020214425 @default.
- W4362657936 creator A5026901794 @default.
- W4362657936 creator A5048836467 @default.
- W4362657936 creator A5069337675 @default.
- W4362657936 creator A5070182290 @default.
- W4362657936 date "2023-04-06" @default.
- W4362657936 modified "2023-09-30" @default.
- W4362657936 title "Molecular characterization of human respiratory syncytial virus in Seoul, South Korea, during 10 consecutive years, 2010–2019" @default.
- W4362657936 cites W1598758802 @default.
- W4362657936 cites W1815870006 @default.
- W4362657936 cites W1981046587 @default.
- W4362657936 cites W1987121081 @default.
- W4362657936 cites W1990430932 @default.
- W4362657936 cites W2010560125 @default.
- W4362657936 cites W2045641296 @default.
- W4362657936 cites W2049373555 @default.
- W4362657936 cites W2055674384 @default.
- W4362657936 cites W2063329669 @default.
- W4362657936 cites W2073852143 @default.
- W4362657936 cites W2075831171 @default.
- W4362657936 cites W2081114699 @default.
- W4362657936 cites W2088549778 @default.
- W4362657936 cites W2094147095 @default.
- W4362657936 cites W2095516835 @default.
- W4362657936 cites W2096641842 @default.
- W4362657936 cites W2098466396 @default.
- W4362657936 cites W2099308320 @default.
- W4362657936 cites W2108512869 @default.
- W4362657936 cites W2111449640 @default.
- W4362657936 cites W2115027861 @default.
- W4362657936 cites W2115035645 @default.
- W4362657936 cites W2118982822 @default.
- W4362657936 cites W2119863754 @default.
- W4362657936 cites W2129808545 @default.
- W4362657936 cites W2130362098 @default.
- W4362657936 cites W2131290103 @default.
- W4362657936 cites W2133999711 @default.
- W4362657936 cites W2136847298 @default.
- W4362657936 cites W2150396170 @default.
- W4362657936 cites W2161433430 @default.
- W4362657936 cites W2163986700 @default.
- W4362657936 cites W2166096923 @default.
- W4362657936 cites W2406524255 @default.
- W4362657936 cites W2409392110 @default.
- W4362657936 cites W2494552277 @default.
- W4362657936 cites W2550620362 @default.
- W4362657936 cites W2614081736 @default.
- W4362657936 cites W2727509207 @default.
- W4362657936 cites W2744019602 @default.
- W4362657936 cites W2763290033 @default.
- W4362657936 cites W2765110787 @default.
- W4362657936 cites W2781938185 @default.
- W4362657936 cites W2799524357 @default.
- W4362657936 cites W2801587458 @default.
- W4362657936 cites W2884030984 @default.
- W4362657936 cites W2884945342 @default.
- W4362657936 cites W2919205146 @default.
- W4362657936 cites W2921779738 @default.
- W4362657936 cites W2951531074 @default.
- W4362657936 cites W2957044739 @default.
- W4362657936 cites W2978725006 @default.
- W4362657936 cites W2998367142 @default.
- W4362657936 cites W3004846127 @default.
- W4362657936 cites W3009099544 @default.
- W4362657936 cites W3012653577 @default.
- W4362657936 cites W3034488945 @default.
- W4362657936 cites W3044260906 @default.
- W4362657936 cites W3048863015 @default.
- W4362657936 cites W3094029233 @default.
- W4362657936 cites W3126687036 @default.
- W4362657936 cites W3172179193 @default.
- W4362657936 cites W3174809557 @default.
- W4362657936 cites W3187454327 @default.
- W4362657936 cites W3203166885 @default.
- W4362657936 cites W4200300037 @default.
- W4362657936 cites W4205262835 @default.
- W4362657936 cites W4212889122 @default.
- W4362657936 cites W4236072174 @default.
- W4362657936 cites W4291111785 @default.
- W4362657936 cites W4310052213 @default.
- W4362657936 doi "https://doi.org/10.1371/journal.pone.0283873" @default.
- W4362657936 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37023101" @default.
- W4362657936 hasPublicationYear "2023" @default.
- W4362657936 type Work @default.
- W4362657936 citedByCount "1" @default.
- W4362657936 countsByYear W43626579362023 @default.
- W4362657936 crossrefType "journal-article" @default.
- W4362657936 hasAuthorship W4362657936A5011178337 @default.
- W4362657936 hasAuthorship W4362657936A5018386699 @default.
- W4362657936 hasAuthorship W4362657936A5020214425 @default.
- W4362657936 hasAuthorship W4362657936A5026901794 @default.
- W4362657936 hasAuthorship W4362657936A5048836467 @default.
- W4362657936 hasAuthorship W4362657936A5069337675 @default.
- W4362657936 hasAuthorship W4362657936A5070182290 @default.