Matches in SemOpenAlex for { <https://semopenalex.org/work/W4362673485> ?p ?o ?g. }
- W4362673485 endingPage "111912" @default.
- W4362673485 startingPage "111912" @default.
- W4362673485 abstract "Conventional wound dressings have several shortcomings because they are unspecific and partially effective for wound healing. To enhance the therapeutic efficiency of wound dressings, we extracted polydeoxyribonucleotides (PDRN) from Patiria pectinifera, and characterized using absorbance-based analysis, chemical composition analysis, and electrophoresis. We evaluated their cytotoxicity and wound healing activity on human dermal fibroblast (HDF) and human keratinocytes (HaCaT). Next, we used electrospinning to fabricate polycaprolactone (PCL)/gelatin (Gel)/PDRN nanofibers for wound dressing application. The average fiber diameters of PCL (P), PCL/Gel (PG), and PCL/Gel/PDRN (PGP) nanofibers were 582.88 ± 202.65, 435.65 ± 149.87, and 334.63 ± 98.09 nm, respectively. The biocompatibility of the nanofibers was assessed using MTT assay and FDA/PI staining on HDF and HaCaT, no cytotoxicity was observed. In vivo experiments with full-thickness skin defect mouse models confirmed that the PGP nanofiber accelerated the initial wound healing process, as shown by wound closure analysis and histological analysis. Our results suggest that the PGP nanofiber has potential as a biomaterial for wound dressing applications and skin tissue engineering." @default.
- W4362673485 created "2023-04-07" @default.
- W4362673485 creator A5008383067 @default.
- W4362673485 creator A5011033919 @default.
- W4362673485 creator A5016264590 @default.
- W4362673485 creator A5057841119 @default.
- W4362673485 creator A5061585719 @default.
- W4362673485 creator A5069292897 @default.
- W4362673485 creator A5076577200 @default.
- W4362673485 creator A5091654903 @default.
- W4362673485 date "2023-05-01" @default.
- W4362673485 modified "2023-10-01" @default.
- W4362673485 title "PCL/gelatin nanofibers incorporated with starfish polydeoxyribonucleotides for potential wound healing applications" @default.
- W4362673485 cites W1944943742 @default.
- W4362673485 cites W1968834637 @default.
- W4362673485 cites W1984418916 @default.
- W4362673485 cites W2013995982 @default.
- W4362673485 cites W2016918034 @default.
- W4362673485 cites W2026763874 @default.
- W4362673485 cites W2056730008 @default.
- W4362673485 cites W2129870757 @default.
- W4362673485 cites W2275458638 @default.
- W4362673485 cites W2465872139 @default.
- W4362673485 cites W2512624221 @default.
- W4362673485 cites W2566399670 @default.
- W4362673485 cites W2572877214 @default.
- W4362673485 cites W2752454166 @default.
- W4362673485 cites W2786317770 @default.
- W4362673485 cites W2798238146 @default.
- W4362673485 cites W2804523516 @default.
- W4362673485 cites W2911261679 @default.
- W4362673485 cites W2945853742 @default.
- W4362673485 cites W2947075584 @default.
- W4362673485 cites W2979877306 @default.
- W4362673485 cites W2980660530 @default.
- W4362673485 cites W3007523428 @default.
- W4362673485 cites W3032961197 @default.
- W4362673485 cites W3035626763 @default.
- W4362673485 cites W3047104964 @default.
- W4362673485 cites W3087770497 @default.
- W4362673485 cites W3092170760 @default.
- W4362673485 cites W3092588675 @default.
- W4362673485 cites W3093224823 @default.
- W4362673485 cites W3108628396 @default.
- W4362673485 cites W3118885706 @default.
- W4362673485 cites W3124763905 @default.
- W4362673485 cites W3139352757 @default.
- W4362673485 cites W3157767428 @default.
- W4362673485 cites W3164729721 @default.
- W4362673485 cites W3173809279 @default.
- W4362673485 cites W3187036838 @default.
- W4362673485 cites W3203284709 @default.
- W4362673485 cites W3207495456 @default.
- W4362673485 cites W4224058698 @default.
- W4362673485 cites W853659202 @default.
- W4362673485 doi "https://doi.org/10.1016/j.matdes.2023.111912" @default.
- W4362673485 hasPublicationYear "2023" @default.
- W4362673485 type Work @default.
- W4362673485 citedByCount "4" @default.
- W4362673485 countsByYear W43626734852023 @default.
- W4362673485 crossrefType "journal-article" @default.
- W4362673485 hasAuthorship W4362673485A5008383067 @default.
- W4362673485 hasAuthorship W4362673485A5011033919 @default.
- W4362673485 hasAuthorship W4362673485A5016264590 @default.
- W4362673485 hasAuthorship W4362673485A5057841119 @default.
- W4362673485 hasAuthorship W4362673485A5061585719 @default.
- W4362673485 hasAuthorship W4362673485A5069292897 @default.
- W4362673485 hasAuthorship W4362673485A5076577200 @default.
- W4362673485 hasAuthorship W4362673485A5091654903 @default.
- W4362673485 hasBestOaLocation W43626734851 @default.
- W4362673485 hasConcept C109316439 @default.
- W4362673485 hasConcept C118995209 @default.
- W4362673485 hasConcept C136229726 @default.
- W4362673485 hasConcept C141071460 @default.
- W4362673485 hasConcept C144796933 @default.
- W4362673485 hasConcept C159985019 @default.
- W4362673485 hasConcept C171250308 @default.
- W4362673485 hasConcept C185592680 @default.
- W4362673485 hasConcept C191897082 @default.
- W4362673485 hasConcept C192562407 @default.
- W4362673485 hasConcept C202751555 @default.
- W4362673485 hasConcept C2777230088 @default.
- W4362673485 hasConcept C2777459323 @default.
- W4362673485 hasConcept C2778005187 @default.
- W4362673485 hasConcept C2778414984 @default.
- W4362673485 hasConcept C2778823387 @default.
- W4362673485 hasConcept C2779868350 @default.
- W4362673485 hasConcept C2780269544 @default.
- W4362673485 hasConcept C2780381497 @default.
- W4362673485 hasConcept C2780783641 @default.
- W4362673485 hasConcept C521977710 @default.
- W4362673485 hasConcept C54355233 @default.
- W4362673485 hasConcept C55493867 @default.
- W4362673485 hasConcept C71924100 @default.
- W4362673485 hasConcept C86803240 @default.
- W4362673485 hasConcept C91129048 @default.
- W4362673485 hasConceptScore W4362673485C109316439 @default.
- W4362673485 hasConceptScore W4362673485C118995209 @default.