Matches in SemOpenAlex for { <https://semopenalex.org/work/W4362732298> ?p ?o ?g. }
- W4362732298 endingPage "90" @default.
- W4362732298 startingPage "80" @default.
- W4362732298 abstract "The aim of this study is to categorize the risk groups of patients with oropharyngeal carcinoma (OPC) according to p16 and p53 status, smoking/alcohol consumption history, and other prognostic factors.The immunostaining of p16 and p53 of 290 patients was retrospectively evaluated. The history of smoking/alcohol consumption of each patient was noted. p16 and p53 staining patterns were reviewed. The results were compared with demographic findings and prognostic factors. Risk groups have been classified for the p16 status of patients.The median follow-up was 47 months (range 6-240). Five-year disease-free survival (DFS) rates for patients with p16 (+) and (-) were 76% and 36%, and overall survival rates were 83% vs 40%, respectively (HR = 0.34 [0.21-0.57], P < .0001), HR = 0.22 [0.12-0.40] P < .0001, respectively). p16(-), p53(+), heavy smoking/alcohol consumption, performance status; advanced T and N stages in patients with p16(-), and continuing smoking/alcohol consumption after treatment were found to be unfavorable risk factors. Five-year overall survival rates were 95%, 78%, and 36% for low, intermediate, and high-risk groups, respectively.The results of our study have shown that p16 negativity in patients with oropharyngeal cancer was found to be an important prognostic factor, especially for those with lower p53 expression and not smoking/consuming alcohol." @default.
- W4362732298 created "2023-04-10" @default.
- W4362732298 creator A5013778534 @default.
- W4362732298 creator A5020151395 @default.
- W4362732298 creator A5021160911 @default.
- W4362732298 creator A5021993209 @default.
- W4362732298 creator A5026010016 @default.
- W4362732298 creator A5030051450 @default.
- W4362732298 creator A5031506285 @default.
- W4362732298 creator A5041552179 @default.
- W4362732298 creator A5047452769 @default.
- W4362732298 creator A5062078256 @default.
- W4362732298 creator A5062271159 @default.
- W4362732298 creator A5067215677 @default.
- W4362732298 creator A5078416201 @default.
- W4362732298 creator A5078996615 @default.
- W4362732298 creator A5079043821 @default.
- W4362732298 creator A5082457157 @default.
- W4362732298 creator A5089945771 @default.
- W4362732298 date "2023-07-01" @default.
- W4362732298 modified "2023-09-27" @default.
- W4362732298 title "The effect of P53 expression and smoking/alcohol in P16(+) and P16(–) oropharyngeal carcinoma and risk classification: the Turkish Society of Radiation Oncology Head & Neck Study Group 01-002" @default.
- W4362732298 cites W1487570541 @default.
- W4362732298 cites W1980180940 @default.
- W4362732298 cites W1985585626 @default.
- W4362732298 cites W1992708996 @default.
- W4362732298 cites W2025974334 @default.
- W4362732298 cites W2045309744 @default.
- W4362732298 cites W2061036339 @default.
- W4362732298 cites W2081735446 @default.
- W4362732298 cites W2089663915 @default.
- W4362732298 cites W2101286915 @default.
- W4362732298 cites W2110664940 @default.
- W4362732298 cites W2117183231 @default.
- W4362732298 cites W2117781588 @default.
- W4362732298 cites W2132087081 @default.
- W4362732298 cites W2134722714 @default.
- W4362732298 cites W2137353992 @default.
- W4362732298 cites W2143680521 @default.
- W4362732298 cites W2460668006 @default.
- W4362732298 cites W2566106337 @default.
- W4362732298 cites W2607491790 @default.
- W4362732298 cites W2766671181 @default.
- W4362732298 cites W2804861361 @default.
- W4362732298 cites W2892045530 @default.
- W4362732298 cites W2901263658 @default.
- W4362732298 cites W2903456675 @default.
- W4362732298 cites W2924642225 @default.
- W4362732298 cites W3031250602 @default.
- W4362732298 cites W3120374595 @default.
- W4362732298 cites W3122345229 @default.
- W4362732298 doi "https://doi.org/10.1016/j.oooo.2023.04.001" @default.
- W4362732298 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37246057" @default.
- W4362732298 hasPublicationYear "2023" @default.
- W4362732298 type Work @default.
- W4362732298 citedByCount "0" @default.
- W4362732298 crossrefType "journal-article" @default.
- W4362732298 hasAuthorship W4362732298A5013778534 @default.
- W4362732298 hasAuthorship W4362732298A5020151395 @default.
- W4362732298 hasAuthorship W4362732298A5021160911 @default.
- W4362732298 hasAuthorship W4362732298A5021993209 @default.
- W4362732298 hasAuthorship W4362732298A5026010016 @default.
- W4362732298 hasAuthorship W4362732298A5030051450 @default.
- W4362732298 hasAuthorship W4362732298A5031506285 @default.
- W4362732298 hasAuthorship W4362732298A5041552179 @default.
- W4362732298 hasAuthorship W4362732298A5047452769 @default.
- W4362732298 hasAuthorship W4362732298A5062078256 @default.
- W4362732298 hasAuthorship W4362732298A5062271159 @default.
- W4362732298 hasAuthorship W4362732298A5067215677 @default.
- W4362732298 hasAuthorship W4362732298A5078416201 @default.
- W4362732298 hasAuthorship W4362732298A5078996615 @default.
- W4362732298 hasAuthorship W4362732298A5079043821 @default.
- W4362732298 hasAuthorship W4362732298A5082457157 @default.
- W4362732298 hasAuthorship W4362732298A5089945771 @default.
- W4362732298 hasConcept C126322002 @default.
- W4362732298 hasConcept C143998085 @default.
- W4362732298 hasConcept C185592680 @default.
- W4362732298 hasConcept C2776530083 @default.
- W4362732298 hasConcept C2777546739 @default.
- W4362732298 hasConcept C2781066024 @default.
- W4362732298 hasConcept C3019635848 @default.
- W4362732298 hasConcept C38180746 @default.
- W4362732298 hasConcept C50440223 @default.
- W4362732298 hasConcept C509974204 @default.
- W4362732298 hasConcept C55493867 @default.
- W4362732298 hasConcept C71924100 @default.
- W4362732298 hasConceptScore W4362732298C126322002 @default.
- W4362732298 hasConceptScore W4362732298C143998085 @default.
- W4362732298 hasConceptScore W4362732298C185592680 @default.
- W4362732298 hasConceptScore W4362732298C2776530083 @default.
- W4362732298 hasConceptScore W4362732298C2777546739 @default.
- W4362732298 hasConceptScore W4362732298C2781066024 @default.
- W4362732298 hasConceptScore W4362732298C3019635848 @default.
- W4362732298 hasConceptScore W4362732298C38180746 @default.
- W4362732298 hasConceptScore W4362732298C50440223 @default.
- W4362732298 hasConceptScore W4362732298C509974204 @default.
- W4362732298 hasConceptScore W4362732298C55493867 @default.
- W4362732298 hasConceptScore W4362732298C71924100 @default.