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- W4362733513 abstract "Immune system modulation is an intriguing part of scientific research. It is well established that the immune system plays a crucial role in orchestrating cellular and molecular key mediators, thus establishing a powerful defense barrier against infectious pathogens. Gut microbiota represent a complex community of approximately a hundred trillion microorganisms that live in the mammalian gastrointestinal (GI) tract, contributing to the maintenance of gut homeostasis via regulation of the innate and adaptive immune responses. However, impairment in the crosstalk between intestinal immunity and gut microbiota may reflect on detrimental health issues. In this context, many studies have indicated that probiotics and their bioactive compounds, such as bacteriocins and short chain fatty acids (SCFAs), display distinct immunomodulatory properties through which they suppress inflammation and enhance the restoration of microbial diversity in pathological states. This review highlights the fundamental features of probiotics, bacteriocins, and SCFAs, which make them ideal therapeutic agents for the amelioration of inflammatory and autoimmune diseases. It also describes their underlying mechanisms on gut microbiota modulation and emphasizes how they influence the function of immune cells involved in regulating gut homeostasis. Finally, it discusses the future perspectives and challenges of their administration to individuals." @default.
- W4362733513 created "2023-04-10" @default.
- W4362733513 creator A5026619440 @default.
- W4362733513 creator A5081329008 @default.
- W4362733513 date "2023-04-09" @default.
- W4362733513 modified "2023-10-05" @default.
- W4362733513 title "Immunomodulatory Properties of Probiotics and Their Derived Bioactive Compounds" @default.
- W4362733513 cites W1486200716 @default.
- W4362733513 cites W1503021066 @default.
- W4362733513 cites W1543844924 @default.
- W4362733513 cites W1544835748 @default.
- W4362733513 cites W1979963523 @default.
- W4362733513 cites W1981266729 @default.
- W4362733513 cites W1983972858 @default.
- W4362733513 cites W2003342633 @default.
- W4362733513 cites W2019795434 @default.
- W4362733513 cites W2034082915 @default.
- W4362733513 cites W2039907390 @default.
- W4362733513 cites W2048502267 @default.
- W4362733513 cites W2051846981 @default.
- W4362733513 cites W2060185417 @default.
- W4362733513 cites W2065139121 @default.
- W4362733513 cites W2072417345 @default.
- W4362733513 cites W2074660641 @default.
- W4362733513 cites W2081024145 @default.
- W4362733513 cites W2090946325 @default.
- W4362733513 cites W2096428863 @default.
- W4362733513 cites W2097959543 @default.
- W4362733513 cites W2107369528 @default.
- W4362733513 cites W2111182398 @default.
- W4362733513 cites W2116175606 @default.
- W4362733513 cites W2122600131 @default.
- W4362733513 cites W2135232490 @default.
- W4362733513 cites W2143544846 @default.
- W4362733513 cites W2143824866 @default.
- W4362733513 cites W2146932682 @default.
- W4362733513 cites W2149074973 @default.
- W4362733513 cites W2165067288 @default.
- W4362733513 cites W2169230713 @default.
- W4362733513 cites W2176673138 @default.
- W4362733513 cites W2188593832 @default.
- W4362733513 cites W2193435259 @default.
- W4362733513 cites W2204185518 @default.
- W4362733513 cites W2233236537 @default.
- W4362733513 cites W2252348097 @default.
- W4362733513 cites W2267931422 @default.
- W4362733513 cites W2297219066 @default.
- W4362733513 cites W2338740599 @default.
- W4362733513 cites W2398989749 @default.
- W4362733513 cites W2409656339 @default.
- W4362733513 cites W2477547149 @default.
- W4362733513 cites W2491805933 @default.
- W4362733513 cites W2521386095 @default.
- W4362733513 cites W2524968973 @default.
- W4362733513 cites W2555739217 @default.
- W4362733513 cites W2560915235 @default.
- W4362733513 cites W2569429048 @default.
- W4362733513 cites W2579549256 @default.
- W4362733513 cites W2607103422 @default.
- W4362733513 cites W2755265257 @default.
- W4362733513 cites W2773324474 @default.
- W4362733513 cites W2787216835 @default.
- W4362733513 cites W2799848487 @default.
- W4362733513 cites W2802288876 @default.
- W4362733513 cites W2806315338 @default.
- W4362733513 cites W2807707689 @default.
- W4362733513 cites W2886540103 @default.
- W4362733513 cites W2887143051 @default.
- W4362733513 cites W2889321792 @default.
- W4362733513 cites W2890686817 @default.
- W4362733513 cites W2894068917 @default.
- W4362733513 cites W2896182701 @default.
- W4362733513 cites W2896767268 @default.
- W4362733513 cites W2897981765 @default.
- W4362733513 cites W2910765752 @default.
- W4362733513 cites W2912605682 @default.
- W4362733513 cites W2913785843 @default.
- W4362733513 cites W2914734699 @default.
- W4362733513 cites W2921966151 @default.
- W4362733513 cites W2929206058 @default.
- W4362733513 cites W2942715272 @default.
- W4362733513 cites W2946273783 @default.
- W4362733513 cites W2954197440 @default.
- W4362733513 cites W2964111984 @default.
- W4362733513 cites W2965837489 @default.
- W4362733513 cites W2966333491 @default.
- W4362733513 cites W2971114720 @default.
- W4362733513 cites W2972142325 @default.
- W4362733513 cites W2979882441 @default.
- W4362733513 cites W2990249310 @default.
- W4362733513 cites W2991131426 @default.
- W4362733513 cites W3000439388 @default.
- W4362733513 cites W3005444990 @default.
- W4362733513 cites W3006297135 @default.
- W4362733513 cites W3009248555 @default.
- W4362733513 cites W3009666649 @default.
- W4362733513 cites W3014353077 @default.
- W4362733513 cites W3017622558 @default.