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- W4363646183 endingPage "360" @default.
- W4363646183 startingPage "348" @default.
- W4363646183 abstract "Over a third of patients surviving acute pulmonary embolism (PE) will experience long-term cardiopulmonary limitations. Persistent thrombi, impaired gas exchange, and altered hemodynamics account for aspects of the postpulmonary embolism syndrome that spans mild functional limitations to debilitating chronic thromboembolic pulmonary hypertension (CTEPH), the most worrisome long-term consequence. Though pulmonary endarterectomy is potentially curative for the latter, less is understood surrounding chronic thromboembolic disease (CTED) and post-PE dyspnea. Advances in pulmonary vasodilator therapies and growing expertise in balloon pulmonary angioplasty provide options for a large group of patients ineligible for surgery, or those with persistent postoperative pulmonary hypertension. In this clinical review, we discuss epidemiology and pathophysiology as well as advances in diagnostics and therapeutics surrounding the spectrum of disease that may follow months after acute PE." @default.
- W4363646183 created "2023-04-11" @default.
- W4363646183 creator A5040791207 @default.
- W4363646183 creator A5049860334 @default.
- W4363646183 creator A5083131245 @default.
- W4363646183 date "2023-04-10" @default.
- W4363646183 modified "2023-09-30" @default.
- W4363646183 title "Chronic thromboembolic pulmonary hypertension and the post-pulmonary embolism (PE) syndrome" @default.
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