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- W4363676306 endingPage "566" @default.
- W4363676306 startingPage "566" @default.
- W4363676306 abstract "Benzydamine is a non-steroidal anti-inflammatory drug with distinct pharmacological properties from other compounds in the same therapeutic class. The differences are structural and pharmacological in nature; the anti-inflammatory mechanism is not strictly explained by the ability to interfere with the synthesis of prostaglandins. The compound is used strictly in local inflammatory diseases (inflammation in the oral and vaginal mucosa). In addition to the therapeutic indications found in the summary of product characteristics (SPC), the compound is used, in high doses, as a psychotropic substance for oral administration, having similar properties to lysergic acid diethylamide (LSD). As an over-the-counter (OTC) compound, it is easy to obtain, and the consequences of using it for purposes other than those assumed by the manufacturer raise various concerns. The reasons are related to the pharmacodynamic and pharmaco-toxicological properties, since neither the mechanism of action nor the possible side effects that would result from systemic consumption, in high doses, even occasionally, have been fully elucidated. The present review aims to analyze the pharmacodynamic properties of benzydamine, starting from the chemical structure, by comparison with structurally similar compounds registered in therapy (as an anti-inflammatory or analgesic) or used for recreational purposes." @default.
- W4363676306 created "2023-04-11" @default.
- W4363676306 creator A5010625682 @default.
- W4363676306 creator A5026953991 @default.
- W4363676306 creator A5029478531 @default.
- W4363676306 creator A5089793314 @default.
- W4363676306 creator A5090356059 @default.
- W4363676306 date "2023-04-10" @default.
- W4363676306 modified "2023-09-30" @default.
- W4363676306 title "Benzydamine—An Affordable Over-the-Counter Drug with Psychoactive Properties—From Chemical Structure to Possible Pharmacological Properties" @default.
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