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• W4363677621 abstract "To verify the prevalence of Potentially pathogenic bacteria (PPB) and their antimicrobial resistance profile in tracheal aspirates of children with tracheostomy and compare it to clinical data. A cross-sectional study was conducted in patients aged 0–18 years who all underwent tracheostomy cannula change (TCC) performed by the Otolaryngology Unit at Hospital de Clínicas de Porto Alegre, Brazil, between October, 2017 and December, 2018. Patients were submitted, at the time of TCC, to a tracheal aspirate through the tracheostomy and secretion was sent to microbiological analysis and antimicrobial susceptibility testing. Clinical data were evaluated through available patients’ electronic medical records. Forty-four patients had their tracheostomy aspirate cultured and all but one presented PPB growth (97.7%). Median age was 3 years-old. Pseudomonas aeruginosa was the most prevalent bacteria (56.9%) and it was resistant to gentamycin, amikacin and cefepime in 36%, 28% and 12% of the culture tests, respectively. P. aeruginosa resistance to gentamycin and to cefepime suggested an association with the number of antibiotic classes used in the 12 months before enrollment (both p = 0.04) and with 2 or more hospital admissions in the same period (p = 0.03 and p = 0.02, respectively). Staphylococcus aureus was isolated in 9.1% and there was no MRSA. It was found a 97.7% prevalence of PPB in the cultured aspirates; the most prevalent bacterium was P. aeruginosa and there was no MRSA identification. Data suggest an association between P. aeruginosa antimicrobial resistance with previous use of antibiotic therapy." @default.
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• W4363677621 date "2023-04-01" @default.
• W4363677621 modified "2023-10-05" @default.
• W4363677621 title "Republication de : Tracheostomized children tracheal colonization and antibiotic resistance profile – A STROBE analysis" @default.
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• W4363677621 doi "https://doi.org/10.1016/j.aforl.2023.02.002" @default.
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